[EN] 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS<br/>[FR] 1H-BENZIMIDAZOLE-5-CARBOXAMIDES COMME AGENTS ANTI-INFLAMMATOIRES
申请人:BOEHRINGER INGELHEIM INT
公开号:WO2010034796A1
公开(公告)日:2010-04-01
There are provided compounds of formula (I), wherein R1, R6, R8, Q2, Q3, Q3a, Q4, L and A have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation and/or cancer.
The invention relates to a compound of formula (I)
wherein A, R
1
-R
6
are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament.
The present invention relates to quinolines, pharmaceutical compositions containing them and their use as antagonists of urotensin II.
本发明涉及喹啉、含有它们的药物组合物以及它们作为尿钠肽II拮抗剂的用途。
Compounds useful as reversible inhibitors of cysteine proteases
申请人:Boehringer Ingelheim Pharmaceuticals Inc.
公开号:US20040063679A1
公开(公告)日:2004-04-01
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (Ia) and (Ib) where R
1
, R
2
, R
3
, R
4
, R
5
, R
6
, R
8
, R
9
and X are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds.
1
1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents
申请人:Pfau Roland
公开号:US20110312935A1
公开(公告)日:2011-12-22
There are provided compounds of formula (I), wherein R
1
, R
6
, R
8
, Q
2
, Q
3
, Q
3a
, Q
4
, L and A have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation and/or cancer.