triphenylsulfonium 2-valeryloxy-1,1-difluoroethanesulfonate | 1048642-00-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: triphenylsulfonium 2-valeryloxy-1,1-difluoroethanesulfonate
• 英文别名: triphenylsulfonium 1,1-difluoro-2-(valeryloxy)ethanesulfonate；Triphenylsulfonium 2-valeryloxy-1,1-difluoroethanesulfonate；1,1-difluoro-2-pentanoyloxyethanesulfonate;triphenylsulfanium
• CAS: 1048642-00-7
• 化学式: C₇H₁₁F₂O₅S*C₁₈H₁₅S
• 分子量: 508.607
• InChiKey: XGVNENXDSWFMHI-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  5.64
• 重原子数：
  34
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  92.9
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  (2-bromo-2,2-difluoro)ethyl valerate 在 sodium dithionite 、 sodium tungstate (VI) dihydrate 、 双氧水 、 碳酸氢钠 作用下， 以 水 、 乙腈 为溶剂， 反应 114.5h， 生成 triphenylsulfonium 2-valeryloxy-1,1-difluoroethanesulfonate
  参考文献：
  名称：

  Compound for Photoacid Generator, Resist Composition Using the Same, and Pattern-Forming Method

  摘要：

  以下是用作优良的辐射敏感性酸发生剂的磺酸醋銨盐的化学式（1）。通过使用含有与化学式（1）对应的磺酸醋銨盐的抗蚀组合物，可以形成良好的图案： 其中R1代表一价有机基团，Q+代表磺銨阳离子或碘銨阳离子。

  公开号：

  US20130130175A1

文献信息

• Processes for Production of 2-Bromo-2,2-Difluoroethanol and 2-(Alkylcarbonyloxy)-1,1-Difluoroethanesulfonic Acid Salt
  申请人：Jodry Jonathan Joachim

  公开号：US20110015431A1

  公开（公告）日：2011-01-20

  Disclosed is a process for producing 2-bromo-2,2-difluoroethanol, which comprises reducing a bromodifluoroacetic acid derivative represented by the formula [1] by using an ate hydride complex as a reducing agent. 2-Bromo-2,2-difluoroethanol thus produced can be used as the starting material to carry out the esterification step, the sulfination step and the oxidation step in this order, thereby producing a 2-alkylcarbonyloxy-1,1-difluoroethanesulfonic acid salt, wherein A represents a substituted or unsubstituted linear, branched or cyclic alkoxy group having 1 to 20 carbon atoms, a substituted or unsubstituted aryloxy group having 6 to 15 carbon atoms, a heteroaryloxy group having 4 to 15 carbon atoms, or a halogen atom.

  揭示了一种生产2-溴-2,2-二氟乙醇的方法，包括使用醇盐氢化物复合物作为还原剂，通过还原由式[1]表示的溴二氟乙酸衍生物来实现。因此生产的2-溴-2,2-二氟乙醇可用作依次进行酯化步骤、磺化步骤和氧化步骤的起始物质，从而产生2-烷基羰氧基-1,1-二氟乙烷磺酸盐，其中A代表具有1至20个碳原子的取代或未取代的线性、支链或环烷氧基团，具有6至15个碳原子的取代或未取代的芳氧基团，具有4至15个碳原子的杂芳氧基团，或卤素原子。
• Processes for Production of 2-Bromo-2,2-Difluoroethanol and 2-(Alkylcarbonyloxy)-1, 1-Difluoroethanesulfonic Acid Salt
  申请人：Jodry Jonathan Joachim

  公开号：US20110319652A1

  公开（公告）日：2011-12-29

  Disclosed is a process for producing 2-bromo-2,2-difluoroethanol, which comprises reducing a bromodifluoroacetic acid derivative represented by the formula [1] by using an ate hydride complex as a reducing agent. 2-Bromo-2,2-difluoroethanol thus produced can be used as the starting material to carry out the esterification step, the sulfination step and the oxidation step in this order, thereby producing a 2-alkylcarbonyloxy-1,1-difluoroethanesulfonic acid salt, wherein A represents a substituted or unsubstituted linear, branched or cyclic alkoxy group having 1 to 20 carbon atoms, a substituted or unsubstituted aryloxy group having 6 to 15 carbon atoms, a heteroaryloxy group having 4 to 15 carbon atoms, or a halogen atom.

  本发明公开了一种生产2-溴-2,2-二氟乙醇的过程，包括使用酸式溴二氟乙酸衍生物[1]通过使用酯基化合物作为还原剂还原。因此，生产的2-溴-2,2-二氟乙醇可以用作开始材料，按照酯化步骤、磺化步骤和氧化步骤的顺序进行，从而生产2-烷基羰氧基-1,1-二氟乙烷磺酸盐，其中A表示具有1至20个碳原子的取代或未取代的线性、支链或环烷氧基团、具有6至15个碳原子的取代或未取代的芳氧基团、具有4至15个碳原子的杂环氧基团或卤素原子。
• Processes for production of 2-bromo-2,2-difluoroethanol and 2-(alkylcarbonyloxy)-1,1-difluoroethanesulfonic acid salt
  申请人：Central Glass Company, Limited

  公开号：US08110711B2

  公开（公告）日：2012-02-07

  Disclosed is a process for producing 2-bromo-2,2-difluoroethanol, which comprises reducing a bromodifluoroacetic acid derivative represented by the formula [1] by using an ate hydride complex as a reducing agent. 2-Bromo-2,2-difluoroethanol thus produced can be used as the starting material to carry out the esterification step, the sulfination step and the oxidation step in this order, thereby producing a 2-alkylcarbonyloxy-1,1-difluoroethanesulfonic acid salt, wherein A represents a substituted or unsubstituted linear, branched or cyclic alkoxy group having 1 to 20 carbon atoms, a substituted or unsubstituted aryloxy group having 6 to 15 carbon atoms, a heteroaryloxy group having 4 to 15 carbon atoms, or a halogen atom.

  本发明揭示了一种生产2-溴-2,2-二氟乙醇的方法，包括使用酸式溴二氟乙酸衍生物[1]通过使用酸式盐水合物还原剂还原。因此生产的2-溴-2,2-二氟乙醇可用作起始材料，按顺序进行酯化步骤、磺化步骤和氧化步骤，从而生成2-烷基羰氧基-1,1-二氟乙烷磺酸盐，其中A代表具有1到20个碳原子的取代或未取代的线性、支链或环状烷氧基，具有6到15个碳原子的取代或未取代的芳氧基，具有4到15个碳原子的杂环氧基或卤素原子。
• Processes for production of 2-bromo-2,2-difluoroethanol and 2-(alkylcarbonyloxy)-1, 1-difluoroethanesulfonic acid salt
  申请人：Central Glass Company, Limited

  公开号：US08222448B2

  公开（公告）日：2012-07-17

  Disclosed is a process for producing 2-bromo-2,2-difluoroethanol, which comprises reducing a bromodifluoroacetic acid derivative represented by the formula [1] by using an ate hydride complex as a reducing agent. 2-Bromo-2,2-difluoroethanol thus produced can be used as the starting material to carry out the esterification step, the sulfination step and the oxidation step in this order, thereby producing a 2-alkylcarbonyloxy-1,1-difluoroethanesulfonic acid salt, wherein A represents a substituted or unsubstituted linear, branched or cyclic alkoxy group having 1 to 20 carbon atoms, a substituted or unsubstituted aryloxy group having 6 to 15 carbon atoms, a heteroaryloxy group having 4 to 15 carbon atoms, or a halogen atom.

  本发明公开了一种制备2-溴-2,2-二氟乙醇的方法，包括使用酸式溴二氟乙酸衍生物[1]并采用酯基铯盐为还原剂还原。所得的2-溴-2,2-二氟乙醇可用作起始物质，依次进行酯化步骤、磺化步骤和氧化步骤，从而制得2-烷基羰氧基-1,1-二氟乙烷磺酸盐，其中A代表具有1至20个碳原子的取代或未取代的线性、支链或环烷氧基基团，具有6至15个碳原子的取代或未取代的芳氧基基团，具有4至15个碳原子的杂环氧基基团或卤素原子。
• 2-(Alkylcarbonyloxy)-1, 1-Difluoroethanesulfonic Acid Salt and Method for Producing the Same
  申请人：Central Glass Company, Limited

  公开号：US20130317250A1

  公开（公告）日：2013-11-28

  By using an organic base when a carboxylic acid bromodifluoroethyl ester is sulfinated by using a sulfinating agent, there is obtained 2-(alkylcarbonyloxy)-1,1-difluoroethanesulfinic acid ammonium salt. By oxidizing the 2-(alkylcarbonyloxy)-1,1-difluoroethanesulfinic acid ammonium salt, there is obtained 2-(alkylcarbonyloxy)-1,1-difluoroethanesulfonic acid ammonium salt. By using the 2-(alkylcarbonyloxy)-1,1-difluoroethanesulfonic acid ammonium salt as a raw material and exchanging it into an onium salt directly or through saponification/esterification, there can be obtained a 2-alkylcarbonyloxy-1,1-difluoroethanesulfonic acid onium salt.

  在使用亚磺酰化试剂对羧酸溴二氟乙酯进行亚磺酰化反应时，使用有机碱，可以得到2-(烷基羰基氧基)-1,1-二氟乙烷亚磺酸铵盐。通过氧化2-(烷基羰基氧基)-1,1-二氟乙烷亚磺酸铵盐，可以得到2-(烷基羰基氧基)-1,1-二氟乙烷磺酸铵盐。通过直接将2-(烷基羰基氧基)-1,1-二氟乙烷磺酸铵盐或通过皂化/酯化交换成离子盐，可以得到2-烷基羰基氧基-1,1-二氟乙烷磺酸离子盐。