1-[1,2-Bis-(diphenyl-phosphinoyl)-ethyl]-4-nitro-benzene | 65206-61-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[1,2-Bis-(diphenyl-phosphinoyl)-ethyl]-4-nitro-benzene
• 英文别名: 1-[1,2-Bis(diphenylphosphoryl)ethyl]-4-nitrobenzene
• CAS: 65206-61-3
• 化学式: C₃₂H₂₇NO₄P₂
• 分子量: 551.518
• InChiKey: VPKAONPAKXKMON-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  39
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  80
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-[1,2-Bis-(diphenyl-phosphinoyl)-ethyl]-4-nitro-benzene 在 titanium(IV) isopropylate 、 三乙氧基硅烷 作用下， 以 苯 为溶剂， 反应 0.42h， 生成 1-(1,2-Bis-diphenylphosphanyl-ethyl)-4-nitro-benzene
  参考文献：
  名称：

  Facile synthesis of chelating bisphosphine oxides and bisphosphines via palladium-catalyzed bishydrophosphinylation reactions

  摘要：

  A series of functional bisphosphosphine oxides were synthesized in good yields via new Pd-catalyzed bis-hydrophosphinylation reactions of terminal alkynes and diphenylphosphine oxide. The resulting bisphosphine oxides were reduced to their corresponding bisphosphines in quantitative yields via a Ti((OPr)-Pr-i)(4)-mediated process. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00609-3
• 作为产物：
  描述：

  1-乙炔基-4-硝基苯 、 Diphenylphosphine oxide 在 四(三苯基膦)钯 作用下， 以 甲苯 为溶剂， 反应 20.0h， 以86%的产率得到1-[1,2-Bis-(diphenyl-phosphinoyl)-ethyl]-4-nitro-benzene
  参考文献：
  名称：

  Facile synthesis of chelating bisphosphine oxides and bisphosphines via palladium-catalyzed bishydrophosphinylation reactions

  摘要：

  A series of functional bisphosphosphine oxides were synthesized in good yields via new Pd-catalyzed bis-hydrophosphinylation reactions of terminal alkynes and diphenylphosphine oxide. The resulting bisphosphine oxides were reduced to their corresponding bisphosphines in quantitative yields via a Ti((OPr)-Pr-i)(4)-mediated process. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00609-3

文献信息

• Facile synthesis of chelating bisphosphine oxides and bisphosphines via palladium-catalyzed bishydrophosphinylation reactions
  作者：Aberdeen Allen、Ling Ma、Wenbin Lin

  DOI：10.1016/s0040-4039(02)00609-3

  日期：2002.5

  A series of functional bisphosphosphine oxides were synthesized in good yields via new Pd-catalyzed bis-hydrophosphinylation reactions of terminal alkynes and diphenylphosphine oxide. The resulting bisphosphine oxides were reduced to their corresponding bisphosphines in quantitative yields via a Ti((OPr)-Pr-i)(4)-mediated process. (C) 2002 Elsevier Science Ltd. All rights reserved.