N-(2,3-diethylindol-1-yl)-1,1-diphenylmethanimine | 1449328-67-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2,3-diethylindol-1-yl)-1,1-diphenylmethanimine
• CAS: 1449328-67-9
• 化学式: C₂₅H₂₄N₂
• 分子量: 352.479
• InChiKey: FKFPZCIOSUYVDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  17.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  二苯甲酮腙 在 叔丁基锂 、 sodium sulfate 、 potassium hydroxide 、 mercury(II) oxide 作用下， 以 乙醚 、 乙醇 、 正戊烷 为溶剂， 反应 7.0h， 生成 N-(2,3-diethylindol-1-yl)-1,1-diphenylmethanimine
  参考文献：
  名称：

  Diazo Compounds as Electrophiles To React with 1,4-Dilithio-1,3-dienes: Efficient Synthesis of 1-Imino-pyrrole Derivatives

  摘要：

  1-Imino-pyrrole and indole derivatives were synthesized in high yields from the reaction of diaryl diazomethanes with 1,4-dilithio-1,3-dienes. Diaryl diazomethanes reacted as electrophiles in this reaction. An unprecedented Zn-complex was formed via transmetalation of the above reaction intermediate with ZnCl2 and was structurally characterized. The trans-mu(2)-eta(1):eta(1) coordination mode in the solid state for this azaallylzinc compound was observed.

  DOI：

  10.1021/ol401878q

文献信息

• Diazo Compounds as Electrophiles To React with 1,4-Dilithio-1,3-dienes: Efficient Synthesis of 1-Imino-pyrrole Derivatives
  作者：Ming Zhan、Shaoguang Zhang、Wen-Xiong Zhang、Zhenfeng Xi

  DOI：10.1021/ol401878q

  日期：2013.8.16

  1-Imino-pyrrole and indole derivatives were synthesized in high yields from the reaction of diaryl diazomethanes with 1,4-dilithio-1,3-dienes. Diaryl diazomethanes reacted as electrophiles in this reaction. An unprecedented Zn-complex was formed via transmetalation of the above reaction intermediate with ZnCl2 and was structurally characterized. The trans-mu(2)-eta(1):eta(1) coordination mode in the solid state for this azaallylzinc compound was observed.