1-Azido-3-[2-(3-azido-2-hydroxypropoxy)ethoxy]propan-2-ol

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: 1-Azido-3-[2-(3-azido-2-hydroxypropoxy)ethoxy]propan-2-ol
• 英文别名: 1-azido-3-[2-(3-azido-2-hydroxypropoxy)ethoxy]propan-2-ol
• 化学式: C₈H₁₆N₆O₄
• 分子量: 260.253
• InChiKey: FUTUQTMLVJKHHS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  18
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  87.6
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1-Azido-3-[2-(3-azido-2-hydroxypropoxy)ethoxy]propan-2-ol 在 四丁基硫酸氢铵 、 copper(l) chloride 、 sodium hydroxide 作用下， 以 甲苯 为溶剂， 反应 36.0h， 生成 4-(azidomethyl)-11-((2-chloroallyl)oxy)-1¹H-3,6,9-trioxa-1(4,1)-triazolacyclododecaphane
  参考文献：
  名称：

  Cu +催化的聚氧乙烯双（叠氮基末端炔烃）交叉环化反应的1,3-偶极分子内点击：合成新的1,2,3-三唑并冠醚

  摘要：

  Cu +催化的聚氧乙烯二（叠氮炔）的1,3-偶极环加成反应产生了以聚氧乙烯1,5-二取代的稠合二（1,2,3-三唑-1,4-氧杂嗪）为混合物的混合物，以及1,4-二取代的单-（1,2,3-三唑）叠氮炔炔冠醚。

  DOI：

  10.1002/jhet.2866
• 作为产物：
  描述：

  乙二醇二缩水甘油醚 在 sodium azide 作用下， 以 甲醇 、 水 为溶剂， 生成 1-Azido-3-[2-(3-azido-2-hydroxypropoxy)ethoxy]propan-2-ol
  参考文献：
  名称：

  Cu +催化的聚氧乙烯双（叠氮基末端炔烃）交叉环化反应的1,3-偶极分子内点击：合成新的1,2,3-三唑并冠醚

  摘要：

  Cu +催化的聚氧乙烯二（叠氮炔）的1,3-偶极环加成反应产生了以聚氧乙烯1,5-二取代的稠合二（1,2,3-三唑-1,4-氧杂嗪）为混合物的混合物，以及1,4-二取代的单-（1,2,3-三唑）叠氮炔炔冠醚。

  DOI：

  10.1002/jhet.2866

文献信息

• 一种一氧化碳荧光胶束探针及应用
  申请人：江苏省电力试验研究院有限公司

  公开号：CN113336728B

  公开（公告）日：2022-03-29

  一种一氧化碳荧光胶束探针及应用，属于一氧化碳检测试纸的制备工艺研究领域。该一氧化碳荧光胶束探针将探针分子置于胶束内，阳离子胶束的表面的正电荷可以相互排斥从而有利于阳离子胶束在试纸上的分散，交联胶束提供了稳定的探针分子环境，在与载体接触后不会使探针分子环境发生变化。一氧化碳在氟代溶剂中相比于其他溶剂有较高的溶解度，氟代胶束中的一氧化碳探针具有更高的检测灵敏度。该荧光胶束探针能够用于锂离子电池安全预警，比色型荧光探针提供的高灵敏优势，为电池快速预警提供了可靠方法。
• Intramolecular 1,3-Dipolar Cycloaddition of Diazido-terminal Dialkynes: Synthesis of New Polyoxyethylene Fused exo-Bis(1,2,3-triazolo-1,4-oxazines)
  作者：Nejib Hussein Mekni

  DOI：10.3987/com-16-13498

  日期：——

  The synthesis of new tetraheterocyclic 1,5-disubstituted exo-heterocyclic polyoxyethylene bis(1,2,3-triazolo-1,4-oxazine) is achieved through nucleophilic azide ion ring opening reaction on polyoxyethylene dioxiranes, followed by an O-propargylation, then thermal uncatalyzed intramolecular cycloaddition.
• Dendritic Polymers With Enhanced Amplification and Interior Functionality
  申请人：Tomalia A. Donald

  公开号：US20070298006A1

  公开（公告）日：2007-12-27

  Dendritic polymers with enhanced amplification and interior functionality are disclosed. These dendritic polymers are made by use of fast, reactive ring-opening chemistry (or other fast reactions) combined with the use of branch cell reagents in a controlled way to rapidly and precisely build dendritic structures, generation by generation, with cleaner chemistry, often single products, lower excesses of reagents, lower levels of dilution, higher capacity method, more easily scaled to commercial dimensions, new ranges of materials, and lower cost. The dendritic compositions prepared have novel internal functionality, greater stability (e.g., thermal stability and less or no reverse Michael's reaction), and reach encapsulation surface densities at lower generations. Unexpectedly, these reactions of polyfunctional branch cell reagents with polyfunctional cores do not create cross-linked materials. Such dendritic polymers are useful as demulsifiers for oil/water emulsions, wet strength agents in the manufacture of paper, proton scavengers, polymers, nanoscale monomers, calibration standards for electron microscopy, making size selective membranes, and agents for modifying viscosity in aqueous formulations such as paint. When these dendritic polymers have a carried material associated with their surface and/or interior, then these dendritic polymers have additional properties for carrying materials due to the unique characteristics of the dendritic polymer, such as for drug delivery, transfection, and diagnostics.
• GAS-GENERATING MATERIAL AND MICRO PUMP
  申请人：SEKISUI CHEMICAL CO., LTD.

  公开号：US20140161687A1

  公开（公告）日：2014-06-12

  Provided is a gas-generating material which can generate a gas in a large amount per unit time and has high storage stability. The gas-generating material 11 a according to the present invention comprises a gas-generating agent that is an azo compound or an azide compound, a tertiary amine, a photosensitizing agent and a binder resin.
• US7985424B2
  申请人：——

  公开号：US7985424B2

  公开（公告）日：2011-07-26