1--1--2-phenyl-2-<(trimethylsilyl)oxy>ethene | 138754-47-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1--1--2-phenyl-2-<(trimethylsilyl)oxy>ethene
• 英文别名: (Z)-2-phenyl-1-N,1-N-di(propan-2-yl)-1-N',1-N'-bis(trimethylsilyl)-2-trimethylsilyloxyethene-1,1-diamine
• CAS: 138754-47-9
• 化学式: C₂₃H₄₆N₂OSi₃
• 分子量: 450.888
• InChiKey: ZTWOYLCNQKOYEQ-FCQUAONHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.25
• 重原子数：
  29
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  15.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  三甲基氯硅烷 、 α-(三甲基硅氧基)苯乙腈 在 四甲基乙二胺 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 为溶剂， 生成 1--1--2-phenyl-2-<(trimethylsilyl)oxy>ethene
  参考文献：
  名称：

  The metalation-silylation of O-trimethylsilyl aldehyde cyanohydrins

  摘要：

  The metalation-trimethylsilyation of O-trimethylsilyl (saturated) aldehyde cyanohydrins was achieved by in situ treatment with LDA and trimethylchlorosilane at -78-degrees-C. C-Silyl products (O-trimethylsilyl acylsilane cyanohydrins) generally predominated, but N-silyl derivatives (ketenimines) were found in some instances. LDA could be added across the C = N bond of the latter. The metalation-trimethylsilylation of O-trimethylsilyl benzaldehyde cyanohydrin could only be effected if 2 equiv of trimethylchlorosilane were employed per equivalent of cyanohydrin anion.

  DOI：

  10.1021/jo00030a030

文献信息

• The metalation-silylation of O-trimethylsilyl aldehyde cyanohydrins
  作者：Robert F. Cunico、Chia P. Kuan

  DOI：10.1021/jo00030a030

  日期：1992.2

  The metalation-trimethylsilyation of O-trimethylsilyl (saturated) aldehyde cyanohydrins was achieved by in situ treatment with LDA and trimethylchlorosilane at -78-degrees-C. C-Silyl products (O-trimethylsilyl acylsilane cyanohydrins) generally predominated, but N-silyl derivatives (ketenimines) were found in some instances. LDA could be added across the C = N bond of the latter. The metalation-trimethylsilylation of O-trimethylsilyl benzaldehyde cyanohydrin could only be effected if 2 equiv of trimethylchlorosilane were employed per equivalent of cyanohydrin anion.