2-Butyl-2-methylpentanedioic acid | 181718-35-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Butyl-2-methylpentanedioic acid
• 英文别名: 2-butyl-2-methylpentanedioic acid
• CAS: 181718-35-4
• 化学式: C₁₀H₁₈O₄
• 分子量: 202.251
• InChiKey: GAEDVPMRQVZKEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  苯胺 、 2-Butyl-2-methylpentanedioic acid 在 4-二甲氨基吡啶 、 N,N'-二环己基碳二亚胺 作用下， 以 甲苯 为溶剂， 反应 2.0h， 生成 3-methyl-3-n-butyl-5-phenylimino-N-phenyl-2-piperidinone
  参考文献：
  名称：

  铜介导的杂环烯丙基硫与有机镁化合物的区域和对映选择性交叉偶联：1,7相对立体生成的情况

  摘要：

  光学活性杂环烯丙基硫化物1–7在CuBr存在下与有机镁化合物反应，以良好的收率和非常高的γ选择性提供光学活性烯烃。区域选择性取决于溶剂以及CuBr∶烯丙基硫化物的比率。杂环核的不对称感应范围为ee的50–98％。这些反应的区域和对映选择性与杂环氮对铜有机基的配位作用有关。

  DOI：

  10.1016/0040-4020(96)00601-1
• 作为产物：
  描述：

  2,6-dimethyl-6-ethenyl-2-decene 在 potassium permanganate 、 sodium periodate 、 potassium carbonate 作用下， 以 水 、 叔丁醇 为溶剂， 反应 2.0h， 生成 2-Butyl-2-methylpentanedioic acid
  参考文献：
  名称：

  铜介导的杂环烯丙基硫与有机镁化合物的区域和对映选择性交叉偶联：1,7相对立体生成的情况

  摘要：

  光学活性杂环烯丙基硫化物1–7在CuBr存在下与有机镁化合物反应，以良好的收率和非常高的γ选择性提供光学活性烯烃。区域选择性取决于溶剂以及CuBr∶烯丙基硫化物的比率。杂环核的不对称感应范围为ee的50–98％。这些反应的区域和对映选择性与杂环氮对铜有机基的配位作用有关。

  DOI：

  10.1016/0040-4020(96)00601-1

文献信息

• Flame retardants with high halogen content and low viscosity
  申请人：Albemarle Corporation

  公开号：EP2107079A2

  公开（公告）日：2009-10-07

  A flame retardant formulation which is the combination of at least (1) at least one bromine-containing polyol flame retardant formed from the reaction of (a) tetrabromophthalic anhydride, (b) an aliphatic polyol, and (c) an epoxide, and (2) at least one aliphatic diester of an alkane dicarboxylic acid, with the proviso that the formulation has a viscosity at 25°C of about 20,000 cps or less, and a bromine content of at least about 40 wt%. A flame retardant compound formed from A) tetrabromophthalic anhydride; B) diethylene glycol; C) at least one alpha-omega alkane diol, or at least one alpha-omega alkane diol and at least one aliphatic monool; and D) at least one alkylene oxide; with the proviso that the compound has a viscosity at 25°C of about 60,000 cps or less, and a bromine content of at least about 43 wt%. Polymer compositions formed from (a) a polyurethane or a polyisocyanurate and (b) a formulation of the invention. One process to make a formulation involves heating a mixture of (a), (b), and at least one liquid aliphatic diester of a alkane dicarboxylic acid to form an intermediate composition; and then the intermediate is contacted one or more times with (c) thereby producing the formulation. Optionally, excess (c) is removed.

  一种阻燃剂配方，它至少是以下物质的组合：(1)至少一种含溴多元醇阻燃剂，由(a)四溴邻苯二甲酸酐、(b)脂肪族多元醇和(c)环氧化物反应生成；(2)至少一种烷烃二羧酸脂肪族二酯，但该配方在 25°C 时的粘度约为 20°C、(2) 烷烃二羧酸的至少一种脂肪族二酯，但该制剂在 25°C 时的粘度不超过约 20,000 cps，溴含量不低于约 40 wt%。由以下物质形成的阻燃化合物：A) 四溴邻苯二甲酸酐；B) 二甘醇；C) 至少一种α-ω-烷二醇，或至少一种α-ω-烷二醇和至少一种脂族一元醇；以及 D) 至少一种环氧亚烷烃；但条件是该化合物在 25°C 时的粘度约为 60,000 cps 或更低，溴含量至少约为 43 wt%。由(a)聚氨酯或聚异氰脲酸酯和(b)本发明配方形成的聚合物组合物。制备配方的一种工艺包括加热(a)、(b)和至少一种烷烃二羧酸的液态脂肪族二酯类的混合物，以形成中间体组合物；然后将中间体与(c)接触一次或多次，从而制得配方。可选择去除多余的 (c)。
• FLAME RETARDANTS WITH HIGH HALOGEN CONTENT AND LOW VISCOSITY
  申请人：ALBEMARLE CORPORATION

  公开号：EP1664179B1

  公开（公告）日：2009-07-15
• FLAME RETARDANT POLYURETHANES AND ADDITIVES THEREFOR
  申请人：ALBEMARLE CORPORATION

  公开号：EP1756224B1

  公开（公告）日：2007-10-17
• Flame Retardants With High Halogen Content and Low Viscosity
  申请人：Feske F. Elbert

  公开号：US20070225517A1

  公开（公告）日：2007-09-27

  Flame retardant formulations comprised of at least one bromine-containing polyol are produced by a process which comprises: A) heating a mixture formed from components comprised of (i) tetrabromophthalic anhydride, (ii) at least one aliphatic polyol, and (iii) at least one liquid straight chain aliphatic diester of a straight-chain alkane dicarboxylic acid to form an intermediate composition; and B) contacting all or a portion of the intermediate composition one or more times with (iv) at least one alkylene oxide that results in the formation of a liquid product formulation, and optionally, removing any excess alkylene oxide present; the amounts of (i), (ii), (iii), and (iv) used being proportioned to form a formulation having a bromine content of at least about 40 wt %, a viscosity at 25° C. of about 20,000 cps or less, and an acid number as determinable by aqueous sodium hydroxide titration and expressed in terms of potassium hydroxide, of less than about 1 milligram of KOH per gram of the formulation.
• Flame Retardant Polyurethanes and Additives Therefor
  申请人：Sjerps Rinus

  公开号：US20070276055A1

  公开（公告）日：2007-11-29

  A free-flowing, stable liquid flame retardant mixture comprised of or formed by mixing together components comprised of: A) at least one organic halogen-containing reactive flame retardant in which the halogen is bromine, chlorine or both; and B) a liquid additive that is comprised of at least one aliphatic polyepoxide of the formula R(EP) n , wherein R is a straight chain or branched chain aliphatic moiety which consists of carbon, hydrogen, and optionally, one or more ether oxygen atoms and/or one or more epoxy oxygen atoms; Ep is a terminal epoxy group: and n is a whole or fractional number in the range of 2 to about 6. Such mixtures can be effectively used in the preparation of flame retardant rigid polyurethanes and rigid foams thereof, and rigid polyisocyanurate and rigid foams thereof. Component B) serves as an effective hardener for such polymers and foams. It is preferable to include in the liquid flame retardant mixture one or more phosphorus-containing flame retardant additives such a fully-esterified ester of a pentavalent acid of phosphorus, e.g., an organic phosphate or organic phosphonate.