2-cyano-3-hydrazineyl-3-(5-phenyl-1H-pyrrol-2-yl)acrylamide | 1340474-94-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-cyano-3-hydrazineyl-3-(5-phenyl-1H-pyrrol-2-yl)acrylamide
• CAS: 1340474-94-3
• 化学式: C₁₄H₁₃N₅O
• 分子量: 267.29
• InChiKey: KCERKUPERCWVIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.86
• 重原子数：
  20.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  120.72
• 氢给体数：
  4.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  2-(1-ethylsulfanyl-2-carbamoyl-2-cyanoethenyl)-5-phenylpyrrole 在 hydrazine hydrate 作用下， 生成 2-cyano-3-hydrazineyl-3-(5-phenyl-1H-pyrrol-2-yl)acrylamide
  参考文献：
  名称：

  A highly selective fluorescent sensor for fluoride anion based on pyrazole derivative: Naked eye “no–yes” detection

  摘要：

  A new pyrazole-based fluorescent sensor, 5-amino-3-(5-phenyl-1H-pyrrol-2-yl)-1H-pyrazole-4-carboxamide (compound 1), was studied for fluoride anion (F-) detection in organic or water-containing solution. This compound displayed both changes in UV-vis absorption and fluorescence emission spectra upon addition of F-. With increasing of F-, blue emission intensity increases drastically and reaches saturation with 607-fold enhancement at 424 nm. The results indicate that compound 1 has highly selectivity for fluoride detection over other anions, such as Cl-, Br-, I-, HSO4-, H2PO4- and AcO- in DMSO or aqueous DMSO solutions. H-1 NMR titration and other experiments confirm that the sensing process is mainly from the deprotonation of the pyrazole-NH in compound 1. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jphotochem.2010.09.012