3-Cyclohexyl-4-methoxyphenol | 65578-66-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-Cyclohexyl-4-methoxyphenol
• CAS: 65578-66-7
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.285
• InChiKey: GQPDSWSLBBXFIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-Cyclohexyl-4-methoxyphenol 在 palladium on activated charcoal sodium hydroxide 、 氢气 、 三溴化硼 、 sodium hydride 作用下， 以 乙醇 为溶剂， 生成 2-[4-(3-Cyclohexyl-4-hydroxyphenoxy)-3,5-dimethylanilino]-2-oxoacetic acid
  参考文献：
  名称：

  Synthesis and biological activity of phenoxyphenyl oxamic acid derivatives related to l-thyronine

  摘要：

  The synthesis of substituted phenoxyphenyl oxamic acid derivatives related to L-thyronine (L-T-3) is described. The in vitro and in vivo cholesterol lowering and cardiovascular effects of these compounds are presented and discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(00)00309-7
• 作为产物：
  描述：

  2-环己基-1,4-苯二醇 在 盐酸 、 potassium carbonate 作用下， 生成 3-Cyclohexyl-4-methoxyphenol
  参考文献：
  名称：

  Synthesis and biological activity of phenoxyphenyl oxamic acid derivatives related to l-thyronine

  摘要：

  The synthesis of substituted phenoxyphenyl oxamic acid derivatives related to L-thyronine (L-T-3) is described. The in vitro and in vivo cholesterol lowering and cardiovascular effects of these compounds are presented and discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(00)00309-7

文献信息

• Re₂O₇catalyzed dienone-phenol rearrangement
  作者：Zilei Xia、Jiadong Hu、Zhigao Shen、Qizheng Yao、Weiqing Xie

  DOI：10.1039/c5ra04931h

  日期：——

  The dienone-phenol rearrangement of 4,4-disubstituted cyclohexadienones catalyzed by Re2O7 has been described. Multi-substituted phenols can be efficiently obtained in good to excellent yields by employing this catalytic protocol.

  已经描述了由Re 2 O 7催化的4，4-二取代的环己二酮的二烯酮-苯酚重排。通过使用该催化方案，可以以良好或优异的收率有效地获得多取代的苯酚。
• YUSUPOV A.; ABDURASULEVA A. R.; ZIYAEV D., (REDKOLLEGIYA UZB. XIM. ZH. AN UZSSR). TASHKENT, 1976. 7 S., BIBLIOGR. 7 +
  作者：YUSUPOV A.、 ABDURASULEVA A. R.、 ZIYAEV D.

  DOI：——

  日期：——
• Synthesis and biological activity of phenoxyphenyl oxamic acid derivatives related to l-thyronine
  作者：James L Stanton、Edna Cahill、Ronald Dotson、Jenny Tan、Hollis C Tomaselli、Jong M Wasvary、Zouhair F Stephan、Ronald E Steele

  DOI：10.1016/s0960-894x(00)00309-7

  日期：2000.8

  The synthesis of substituted phenoxyphenyl oxamic acid derivatives related to L-thyronine (L-T-3) is described. The in vitro and in vivo cholesterol lowering and cardiovascular effects of these compounds are presented and discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.