2-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-isoindole-1,3-dione | 150225-29-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-isoindole-1,3-dione
• 英文别名: 2-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoroundecyl)isoindole-1,3-dione
• CAS: 150225-29-9
• 化学式: C₁₉H₁₀F₁₇NO₂
• 分子量: 607.267
• InChiKey: XIJINZGKCJENMA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8
• 重原子数：
  39
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  19

反应信息

• 作为反应物：
  描述：

  2-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-isoindole-1,3-dione 在 一水合肼 、 盐酸 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以77%的产率得到4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-十七氟十一胺
  参考文献：
  名称：

  Improved synthesis of perfluorooctylpropyl amine

  摘要：

  Hydrazinolysis of N-perfluorooctylpropyl phthalimide is an easy route to scale up for the title compound. Both the alkylation of potassium phthalimide with perfluorooctylpropyl iodide and the hydrogenolysis of the adduct of perfluoroctyl iodide to N-allyl-phthalimide provide this amine precursor in good yields. The latter procedure, however, has a better atom economy, since it requires only three steps from perfluorooctyl iodide. (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2004.02.006
• 作为产物：
  描述：

  N-烯丙基邻苯二甲酰亚胺 在 palladium on activated charcoal 偶氮二异丁腈 、 氢气 、 三乙胺 作用下， 以 四氢呋喃 、 异辛烷 为溶剂， 20.0~70.0 ℃ 、344.74 kPa 条件下， 反应 46.0h， 生成 2-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecyl)-isoindole-1,3-dione
  参考文献：
  名称：

  Improved synthesis of perfluorooctylpropyl amine

  摘要：

  Hydrazinolysis of N-perfluorooctylpropyl phthalimide is an easy route to scale up for the title compound. Both the alkylation of potassium phthalimide with perfluorooctylpropyl iodide and the hydrogenolysis of the adduct of perfluoroctyl iodide to N-allyl-phthalimide provide this amine precursor in good yields. The latter procedure, however, has a better atom economy, since it requires only three steps from perfluorooctyl iodide. (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2004.02.006

文献信息

• Improved synthesis of perfluorooctylpropyl amine
  作者：Abudurexiti Abulikemu、Gábor Halász、Antal Csámpai、Ágnes Gömöry、József Rábai

  DOI：10.1016/j.jfluchem.2004.02.006

  日期：2004.7

  Hydrazinolysis of N-perfluorooctylpropyl phthalimide is an easy route to scale up for the title compound. Both the alkylation of potassium phthalimide with perfluorooctylpropyl iodide and the hydrogenolysis of the adduct of perfluoroctyl iodide to N-allyl-phthalimide provide this amine precursor in good yields. The latter procedure, however, has a better atom economy, since it requires only three steps from perfluorooctyl iodide. (C) 2004 Elsevier B.V. All rights reserved.