4-amino-4'-nitroazofurazan | 155438-11-2

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: 4-amino-4'-nitroazofurazan
• 英文别名: 1,2,5-Oxadiazol-3-amine, 4-[(4-nitro-1,2,5-oxadiazol-3-yl)azo]-；4-[(4-nitro-1,2,5-oxadiazol-3-yl)diazenyl]-1,2,5-oxadiazol-3-amine
• CAS: 155438-11-2
• 化学式: C₄H₂N₈O₄
• 分子量: 226.111
• InChiKey: ZDOVUEIQDWPQDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  174
• 氢给体数：
  1
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  4-amino-4'-nitroazofurazan 在 氨 作用下， 以 氯仿 为溶剂， 以96%的产率得到3,3'-diamino-4,4'-azofurazan
  参考文献：
  名称：

  摘要：

  The reactions of 3-nitro-4-R-furazans with ammonia were studied. The effect of the substituent R on the specific features of the nucleophilic substitution reaction observed was considered. The nitro group attached to the furazan ring can act as both the leaving group and the activating group facilitating the displacement of the second substituent (for example, OR' or N(NO2)R').

  DOI：

  10.1023/a:1020931511013
• 作为产物：
  描述：

  4,4'-dinitroazofurazan 在 氨 作用下， 以 氯仿 为溶剂， 反应 0.33h， 以79%的产率得到4-amino-4'-nitroazofurazan
  参考文献：
  名称：

  摘要：

  The reactions of 3-nitro-4-R-furazans with ammonia were studied. The effect of the substituent R on the specific features of the nucleophilic substitution reaction observed was considered. The nitro group attached to the furazan ring can act as both the leaving group and the activating group facilitating the displacement of the second substituent (for example, OR' or N(NO2)R').

  DOI：

  10.1023/a:1020931511013

文献信息

• (Difluoroamino)furazans
  作者：B. I. Ugrak、T. K. Shkineva、A. B. Sheremetev、I. L. Dalinger

  DOI：10.1007/s11172-023-4076-7

  日期：2023.11

  3-Amino-4-R-furazans can be converted into the corresponding 3-difluoroamino-4-R-furazans by fluorination with a fluorine—argon mixture under both liquid-phase and solid-phase conditions. Fluorinations can be enabled in the presence of both electron-donating and electron-withdrawing substituents R; some substituents R underwent transformations under fluorination conditions.

  3-氨基-4-R-呋喃嗪可以通过在液相和固相条件下用氟-氩混合物氟化而转化为相应的3-二氟氨基-4-R-呋喃嗪。在给电子和吸电子取代基 R 存在的情况下可以发生氟化；一些取代基R在氟化条件下发生转变。
• Sheremetev; Kharitonova; Mantseva, Russian Journal of Organic Chemistry, 1999, vol. 35, # 10, p. 1525 - 1537
  作者：Sheremetev、Kharitonova、Mantseva、Kulagina、Shatunova、Aleksandrova、Mel'nikova、Ivanova、Dmitriev、Eman、Yudin、Kuz'min、Strelenko、Novikova、Lebedev、Khmel'nitskii

  DOI：——

  日期：——
• ——
  作者：A. B. Sheremetev、V. O. Kulagina、I. A. Kryazhevskikh、T. M. Melnikova、N. S. Aleksandrova

  DOI：10.1023/a:1020931511013

  日期：——

  The reactions of 3-nitro-4-R-furazans with ammonia were studied. The effect of the substituent R on the specific features of the nucleophilic substitution reaction observed was considered. The nitro group attached to the furazan ring can act as both the leaving group and the activating group facilitating the displacement of the second substituent (for example, OR' or N(NO2)R').