4-[(1-hydroperoxycyclohexyl)oxy]-1-methoxy-1-methylbutyl hydroperoxide | 194297-74-0

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机氢过氧化物
• 英文名称: 4-[(1-hydroperoxycyclohexyl)oxy]-1-methoxy-1-methylbutyl hydroperoxide
• 英文别名: 1-Hydroperoxy-1-(4-hydroperoxy-4-methoxypentoxy)cyclohexane
• CAS: 194297-74-0
• 化学式: C₁₂H₂₄O₆
• 分子量: 264.319
• InChiKey: SHPGOOSFLRQNBG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  77.4
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4-[(1-hydroperoxycyclohexyl)oxy]-1-methoxy-1-methylbutyl hydroperoxide 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以38%的产率得到9-methyl-7,8,13-trioxaspiro[5.7]tridecan-9-yl hydroperoxide
  参考文献：
  名称：

  Synthesis of Hydroxy(or Hydroperoxy)-Substituted 1,2,4-Trioxacycloalkanes by the Ozonolysis of Unsaturated Hydroperoxy Acetals

  摘要：

  Ozonolyses of unsaturated hydroperoxy acetals 4a-k gave in each case the mixtures of products containing the corresponding trioxanes 8a-f and 12e,f, trioxepanes 12g-i, trioxocane 12j, and trioxonane 12k. By choosing the proper conditions of the ozonolysis, the desired cyclic peroxide was selectively obtained in moderate to good yield. Alternatively, acid-catalyzed cyclization of the methanol-derived ozonolysis products 13h and 13j provided the corresponding trioxepane 12h and trioxocane 12j, respectively.

  DOI：

  10.1021/jo970555l
• 作为产物：
  描述：

  (甲氧基亚甲基)环己烷 在 臭氧 作用下， 以 乙醚 、 二氯甲烷 为溶剂， 生成 4-[(1-hydroperoxycyclohexyl)oxy]-1-methoxy-1-methylbutyl hydroperoxide
  参考文献：
  名称：

  Synthesis of Hydroxy(or Hydroperoxy)-Substituted 1,2,4-Trioxacycloalkanes by the Ozonolysis of Unsaturated Hydroperoxy Acetals

  摘要：

  Ozonolyses of unsaturated hydroperoxy acetals 4a-k gave in each case the mixtures of products containing the corresponding trioxanes 8a-f and 12e,f, trioxepanes 12g-i, trioxocane 12j, and trioxonane 12k. By choosing the proper conditions of the ozonolysis, the desired cyclic peroxide was selectively obtained in moderate to good yield. Alternatively, acid-catalyzed cyclization of the methanol-derived ozonolysis products 13h and 13j provided the corresponding trioxepane 12h and trioxocane 12j, respectively.

  DOI：

  10.1021/jo970555l

文献信息

• Synthesis of Hydroxy(or Hydroperoxy)-Substituted 1,2,4-Trioxacycloalkanes by the Ozonolysis of Unsaturated Hydroperoxy Acetals
  作者：Yoshihiro Ushigoe、Yuko Torao、Araki Masuyama、Masatomo Nojima

  DOI：10.1021/jo970555l

  日期：1997.7.1

  Ozonolyses of unsaturated hydroperoxy acetals 4a-k gave in each case the mixtures of products containing the corresponding trioxanes 8a-f and 12e,f, trioxepanes 12g-i, trioxocane 12j, and trioxonane 12k. By choosing the proper conditions of the ozonolysis, the desired cyclic peroxide was selectively obtained in moderate to good yield. Alternatively, acid-catalyzed cyclization of the methanol-derived ozonolysis products 13h and 13j provided the corresponding trioxepane 12h and trioxocane 12j, respectively.