1,1-Di(2-pyridyl)-1-methoxy-1-<3-<(tert-butyldimethylsilyl)oxy>phenyl>methane N,N'-dioxide | 1027887-51-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1-Di(2-pyridyl)-1-methoxy-1-<3-<(tert-butyldimethylsilyl)oxy>phenyl>methane N,N'-dioxide
• 英文别名: Tert-butyl-[3-[methoxy-bis(1-oxidopyridin-1-ium-2-yl)methyl]phenoxy]-dimethylsilane
• CAS: 1027887-51-9
• 化学式: C₂₄H₃₀N₂O₄Si
• 分子量: 438.599
• InChiKey: FEEJGMBRNAYHDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.28
• 重原子数：
  31
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  69.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,1-Di(2-pyridyl)-1-methoxy-1-<3-<(tert-butyldimethylsilyl)oxy>phenyl>methane N,N'-dioxide 在 盐酸 、 二甲氨基甲酰氯 作用下， 以 乙醇 为溶剂， 反应 21.0h， 生成 1,1-Bis(6-cyano-2-pyridyl)-1-methoxy-1-(3-hydroxyphenyl)methane
  参考文献：
  名称：

  Synthesis and Coordination Properties of Pendant Arm Dipyridylmethane Derivatives

  摘要：

  Dipyridylmetane dicarboxylic acids with pendant arms containing pyridine groups were prepared. Cu(II) was shown to form square pyramidal complexes with the ligands. Depending on the structure of the pendant arm, the apical position was occupied either by a water molecule or by a pyridyl group from the same molecule or form a neighboring molecule. The reason for the different behavior of the ligands is suggested to be due to stereoelectronically induced conformational preferences of the ligands.

  DOI：

  10.1021/jo00087a012
• 作为产物：
  描述：

  1-溴-3-(特-丁基二甲基硅氧基)苯 在 sodium hydride 、 magnesium 、 1,2-二溴乙烷 、 间氯过氧苯甲酸 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 80.0h， 生成 1,1-Di(2-pyridyl)-1-methoxy-1-<3-<(tert-butyldimethylsilyl)oxy>phenyl>methane N,N'-dioxide
  参考文献：
  名称：

  Synthesis and Coordination Properties of Pendant Arm Dipyridylmethane Derivatives

  摘要：

  Dipyridylmetane dicarboxylic acids with pendant arms containing pyridine groups were prepared. Cu(II) was shown to form square pyramidal complexes with the ligands. Depending on the structure of the pendant arm, the apical position was occupied either by a water molecule or by a pyridyl group from the same molecule or form a neighboring molecule. The reason for the different behavior of the ligands is suggested to be due to stereoelectronically induced conformational preferences of the ligands.

  DOI：

  10.1021/jo00087a012

文献信息

• Synthesis and Coordination Properties of Pendant Arm Dipyridylmethane Derivatives
  作者：Hans Adolfsson、Kenneth Waernmark、Christina Moberg

  DOI：10.1021/jo00087a012

  日期：1994.4

  Dipyridylmetane dicarboxylic acids with pendant arms containing pyridine groups were prepared. Cu(II) was shown to form square pyramidal complexes with the ligands. Depending on the structure of the pendant arm, the apical position was occupied either by a water molecule or by a pyridyl group from the same molecule or form a neighboring molecule. The reason for the different behavior of the ligands is suggested to be due to stereoelectronically induced conformational preferences of the ligands.