(9Z,12Z,15Z,18Z)-tetracosa-9,12,15,18-tetraenoic acid | 3508-03-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (9Z,12Z,15Z,18Z)-tetracosa-9,12,15,18-tetraenoic acid
• 英文别名: all-cis-9,12,15,18-tetracosatetraenoic acid；Tetracosatetraenoic acid (24:4n-6)
• CAS: 3508-03-0
• 化学式: C₂₄H₄₀O₂
• 分子量: 360.58
• InChiKey: MMJZTSLHOIGZPU-DOFZRALJSA-N

物化性质

• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  8.7
• 重原子数：
  26
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  9-癸炔酸 在 钯 氢气 作用下， 以 甲醇 为溶剂， 生成 (9Z,12Z,15Z,18Z)-tetracosa-9,12,15,18-tetraenoic acid
  参考文献：
  名称：

  Myagkova,G.I. et al., Journal of Organic Chemistry USSR (English Translation), 1965, vol. 1, p. 987 - 989

  摘要：

  DOI：

文献信息

• [EN] PROCESS FOR INCREASING THE STABILITY OF A COMPOSITION COMPRISING POLYUNSATURATED OMEGA-6 FATTY ACIDS<br/>[FR] PROCÉDÉ D'AUGMENTATION DE LA STABILITÉ D'UNE COMPOSITION COMPRENANT DES ACIDES GRAS OMÉGA-6 POLYINSATURÉS
  申请人：EVONIK DEGUSSA GMBH

  公开号：WO2016102316A1

  公开（公告）日：2016-06-30

  The present invention relates to processes for increasing the stability of compositions comprising polyunsaturated omega-6 fatty acids against oxidation. The processes comprise the following steps: (i) providing a starting composition comprising at least one polyunsaturated omega-6 fatty acid component; (ii) providing a lysine composition; (iii) admixing aqueous, aqueous-alcoholic or alcoholic solutions of starting composition and lysine composition, and subjecting resulting admixture to spray drying conditions subsequently, thus forming a solid product composition comprising at least one salt of a cation derived from lysine with an anion derived from a polyunsaturated omega-6 fatty acid; the product composition exhibiting a solvent content SC selected from the following: SC < 5 wt%, SC < 3 wt%, SC < 1 wt%, SC < 0.5 wt%. Compositions obtainable by such spray drying processes and use of such compositions for the manufacture of food, nutritional and pharmaceutical products are further comprised by the present invention.

  本发明涉及增加含有多不饱和ω-6脂肪酸的组合物抗氧化稳定性的过程。该过程包括以下步骤：(i)提供包含至少一种多不饱和ω-6脂肪酸成分的起始组合物；(ii)提供赖氨酸组合物；(iii)混合起始组合物和赖氨酸组合物的水、水醇或醇溶液，并随后将所得混合物暴露于喷雾干燥条件，从而形成包含至少一种来自赖氨酸阳离子和来自多不饱和ω-6脂肪酸阴离子的盐的固体产品组合物；所述产品组合物具有以下所选的溶剂含量SC：SC < 5 wt%，SC < 3 wt%，SC < 1 wt%，SC < 0.5 wt%。通过这种喷雾干燥过程获得的组合物以及利用这种组合物制造食品、营养和制药产品的方法也包含在本发明中。
• AMINO ACID SALTS OF UNSATURATED FATTY ACIDS
  申请人：Thetis Pharmaceuticals LLC

  公开号：US20170119841A1

  公开（公告）日：2017-05-04

  The present invention provides compounds of Formula I and Formula II and related compositions and methods.

  本发明提供了Formula I和Formula II的化合物以及相关的组合物和方法。
• METHODS OF METAL OXIDE NANOCRYSTALS PREPARATION
  申请人：CNI Innovations

  公开号：US20150291501A1

  公开（公告）日：2015-10-15

  Embodiments relate to methods of metal oxide nanocrystals preparation. In embodiments, a metal-organic precursor may be economically synthesized by reacting a metal with an organic acid. The organic acid may include an aliphatic chain longer than three carbon atoms. The metal may be In, Sn, Al, Ga, Zn, Cd, Sb, Bi, Ge, Mn, Ti, Nb, V, Cr, Mo, Fe, Y, Mg, Co, as well as mixtures thereof. Further processing of the metal-organic precursor (e.g. by pyrolysis, hydrolysis, or alcoholysis) produces metal oxide nanocrystals of desired characteristics. An metal-organic precursor of indium tin oxide (ITO) may be synthesized by reacting indium metal and tin metal with an organic acid having an aliphatic chain longer than three carbon atoms (e.g. stearic acid) at a temperature above 200° C. Further processing of the resulting metal-organic precursor yields ITO nanocrystals of regular shape, uniform size, and average diameter ranging of between about 1-500 nm.

  实施例涉及金属氧化物纳米晶体制备方法。在实施例中，可以通过将金属与有机酸反应来经济地合成金属有机前体。有机酸可以包括长于三个碳原子的脂肪链。金属可以是In、Sn、Al、Ga、Zn、Cd、Sb、Bi、Ge、Mn、Ti、Nb、V、Cr、Mo、Fe、Y、Mg、Co以及其混合物。进一步处理金属有机前体（例如通过热解、水解或醇解）可产生所需特性的金属氧化物纳米晶体。可以通过将长于三个碳原子的有机酸（例如硬脂酸）与铟金属和锡金属在200℃以上的温度下反应来合成氧化铟锡（ITO）的金属有机前体。进一步处理所得金属有机前体可得到形状规则、尺寸均匀、平均直径约为1-500纳米的ITO纳米晶体。
• Mineral Amino-Acid Complexes of Active Agents
  申请人：Thetis Pharmaceuticals LLC

  公开号：US20160199385A1

  公开（公告）日：2016-07-14

  The present invention provides compounds of Formula I and related compositions and methods.

  本发明提供了I式化合物及相关组合物和方法。
• Compositions and Methods Relating to Ionic Salts of Peptides
  申请人：THETIS PHARMACEUTICALS LLC

  公开号：US20160107985A1

  公开（公告）日：2016-04-21

  The present invention relates to compounds of Formula I, compositions containing same, and methods of use.

  本发明涉及式I的化合物，含有该化合物的组合物以及使用方法。