2-己烯-1-基丁二酸酐 | 10500-34-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2-己烯-1-基丁二酸酐
• 中文别名: 2-己烯-1-琥珀酸酐；2-己烯-1-基丁二酸酐(异构体的混合物)
• 英文名称: Hexen-(2)-ylbernsteinaeureanhydrid
• 英文别名: (Hexen-2-yl)-bernsteinsaeureanhydrid；(+/-)-hex-2ξ-enyl-succinic acid-anhydride；(+/-)-Hex-2ξ-enyl-bernsteinsaeure-anhydrid；2,5-Furandione, 3-(2-hexen-1-yl)dihydro-；3-hex-2-enyloxolane-2,5-dione
• CAS: 10500-34-2
• 化学式: C₁₀H₁₄O₃
• 分子量: 182.219
• InChiKey: VWXVGDSPDMSWFP-UHFFFAOYSA-N

物化性质

• 密度：
  1.07
• LogP：
  1.519 (est)
• 稳定性/保质期：
  遵照规格使用和储存，则不会分解。

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2917190090

SDS

2-Hexen-1-ylsuccinic Anhydride (cis- and trans-
mixture)
SAFETY DATA SHEET

---

Section 1. IDENTIFICATION
Product name: 2-Hexen-1-ylsuccinic Anhydride (cis- and trans- mixture)

---

Section 2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDS Not classified
HEALTH HAZARDS
Skin corrosion/irritation Category 2
Category 2A
Serious eye damage/eye irritation
ENVIRONMENTAL HAZARDS Not classified
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Warning
Signal word
Hazard statements Causes skin irritation
Causes serious eye irritation
Precautionary statements:
Wash hands thoroughly after handling.
[Prevention]
Wear protective gloves/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
[Response]
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash before reuse.

---

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture: Substance
2-Hexen-1-ylsuccinic Anhydride (cis- and trans- mixture)
Components:
Percent: ....
10500-34-2
CAS Number:
Chemical Formula: C10H14O3

---

Section 4. FIRST AID MEASURES
Inhalation: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Get medical advice/attention if you feel unwell.
mixture)

---

Section 4. FIRST AID MEASURES
Skin contact: Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion: Get medical advice/attention if you feel unwell. Rinse mouth.
A rescuer should wear personal protective equipment, such as rubber gloves and air-
Protection of first-aiders:
tight goggles.

---

Section 5. FIRE-FIGHTING MEASURES
Suitable extinguishing Dry chemical, foam, water spray, carbon dioxide.
media:
Unsuitable extinguishing Solid streams of water
media:
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protective When extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

---

Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Ensure adequate ventilation. Entry to non-involved personnel should be controlled
emergency procedures: around the leakage area by roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Absorb spilled material in a suitable absorbent (e.g. rag, dry sand, earth, saw-dust).
containment and cleaning In case of large amount of spillage, contain a spill by bunding. Adhered or collected
up: material should be promptly disposed of, in accordance with appropriate laws and
regulations.

---

Section 7. HANDLING AND STORAGE
Precautions for safe handling
Technical measures: Handling is performed in a well ventilated place. Wear suitable protective equipment.
Prevent generation of vapour or mist. Wash hands and face thoroughly after
handling.
Use a ventilation, local exhaust if vapour or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions: Keep container tightly closed. Store in a cool and dark place.
Store under inert gas.
Protect from moisture.
Store away from incompatible materials such as oxidizing agents.
Moisture-sensitive
Packaging material: Comply with laws.

---

Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls: Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Vapor respirator. Follow local and national regulations.
Protective gloves.
Hand protection:
Eye protection: Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.
mixture)

---

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C): Liquid
Clear
Form:
Colour: Colorless - Pale yellow
No data available
Odour:
pH: No data available
Melting point/freezing point:No data available
Boiling point/range: No data available
No data available
Flash point:
Flammability or explosive
limits:
Lower: No data available
Upper: No data available
Relative density: 1.07
Solubility(ies):
[Water] No data available
No data available
[Other solvents]

---

Section 10. STABILITY AND REACTIVITY
Chemical stability: Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide
products:

---

Section 11. TOXICOLOGICAL INFORMATION
No data available
Acute Toxicity:
Skin corrosion/irritation: No data available
No data available
Serious eye
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
No data available
IARC =
NTP = No data available
No data available
Reproductive toxicity:

---

Section 12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence / degradability: No data available
Bioaccumulative No data available
potential(BCF):
Mobility in soil
Log Pow: No data available
Soil adsorption (Koc): No data available
Henry's Law No data available
constant(PaM3/mol):

---

Section 13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to burn in a chemical
incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when
disposing of the substance.
mixture)

---

Section 14. TRANSPORT INFORMATION
Hazards Class: Does not correspond to the classification standard of the United Nations
UN-No: Not listed

---

Section 15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  2-己烯-1-基丁二酸酐 在 potassium carbonate 作用下， 生成 己-2-烯基-琥珀酸
  参考文献：
  名称：

  Agami,C. et al., Bulletin de la Societe Chimique de France, 1966, p. 1195 - 1201

  摘要：

  DOI：
• 作为产物：
  描述：

  马来酸酐 、 1-己烯 在 苯 作用下， 生成 2-己烯-1-基丁二酸酐
  参考文献：
  名称：

  The Potential Influence of Climate Change on Offshore Primary Production in Lake Michigan

  摘要：

  This paper examines the potential influence of climate change on the primary productivity of Lake Michigan. Two general circulation models (GCMs) provided physical information on projected regional climate for the years 2030, 2050, and 2090. A 30-year record of meteorological data and limnological observations, from 1961 to through,1990, was used to define present, baseline conditions for the lake. GCM output was used to develop scenarios of future thermal characteristics, mixing patterns, and surface irradiance, which were then used to drive primary production calculations. Mean annual primary production for the base period was 116 g C/m(2). Under base conditions thermal stratification of the lake occurred on 13 June and extended 135 days until 26 October. Conditions projected for 2090 showed the mean date of stratification beginning as early as 5 April and remaining for 225 days until 20 November. Estimated mean annual primary production under these conditions totaled 113 g C/m(2), a decrease of 3% from the mean base value. Under the most extreme conditions of maximum projected cloud cover for 2090, primary production in that year could fall to 101 g C/m(2), a decrease of 13% from the base mean, or down 22% from maximum base production calculated under minimum base cloud cover conditions. The projected decrease may be attributed to physical/chemical constraints imposed on spring primary production by altered climate conditions. Early stratification would shorten the period of winter-spring mixing, during which time nutrients from the sediment are transported to the productive euphotic zone. The spring bloom was projected to diminish if early stratification capped the nutrient supply, and increased cloud cover reduced light input for photosynthesis. To a lesser extent fall production could also be reduced by the extension of the stratified period. Altered physical/chemical conditions influenced by a changing climate will be an important factor to consider in assessing future water quality conditions, primary production and the food web dynamics of the Great Lakes.

  DOI：

  10.1016/s0380-1330(02)70608-4

文献信息

• Phthalazinone derivatives
  申请人：KuDOS Pharmaceuticals Limited

  公开号：US20040023968A1

  公开（公告）日：2004-02-05

  A compound of formula: 1 or an isomer, salt, solvate, chemically protected form, or prodrug thereof, wherein A and B together represent an optionally substituted, fused aromatic ring; R L is a C 5-7 aryl group substituted in the meta position by the group R 2 , and optionally further substituted; wherein R 2 is selected from: 2 and its use as a pharmaceutical, in particular for the treatment of diseases ameliorated by inhibiting the activity of PARP.

  一种化合物，其分子式为1或其异构体、盐、溶剂合物、化学保护形式或前药，其中A和B在一起代表一个可选取代的融合芳香环；RL是一个C5-7芳基基团，在meta位被R2基团取代，且可选取进一步取代；其中R2被选自：2，并且它被用作一种药物，特别是用于治疗通过抑制PARP活性改善的疾病。
• The Potential Influence of Climate Change on Offshore Primary Production in Lake Michigan
  作者：Arthur S. Brooks、John C. Zastrow

  DOI：10.1016/s0380-1330(02)70608-4

  日期：2002.1

  This paper examines the potential influence of climate change on the primary productivity of Lake Michigan. Two general circulation models (GCMs) provided physical information on projected regional climate for the years 2030, 2050, and 2090. A 30-year record of meteorological data and limnological observations, from 1961 to through,1990, was used to define present, baseline conditions for the lake. GCM output was used to develop scenarios of future thermal characteristics, mixing patterns, and surface irradiance, which were then used to drive primary production calculations. Mean annual primary production for the base period was 116 g C/m(2). Under base conditions thermal stratification of the lake occurred on 13 June and extended 135 days until 26 October. Conditions projected for 2090 showed the mean date of stratification beginning as early as 5 April and remaining for 225 days until 20 November. Estimated mean annual primary production under these conditions totaled 113 g C/m(2), a decrease of 3% from the mean base value. Under the most extreme conditions of maximum projected cloud cover for 2090, primary production in that year could fall to 101 g C/m(2), a decrease of 13% from the base mean, or down 22% from maximum base production calculated under minimum base cloud cover conditions. The projected decrease may be attributed to physical/chemical constraints imposed on spring primary production by altered climate conditions. Early stratification would shorten the period of winter-spring mixing, during which time nutrients from the sediment are transported to the productive euphotic zone. The spring bloom was projected to diminish if early stratification capped the nutrient supply, and increased cloud cover reduced light input for photosynthesis. To a lesser extent fall production could also be reduced by the extension of the stratified period. Altered physical/chemical conditions influenced by a changing climate will be an important factor to consider in assessing future water quality conditions, primary production and the food web dynamics of the Great Lakes.
• Agami,C. et al., Bulletin de la Societe Chimique de France, 1966, p. 1195 - 1201
  作者：Agami,C. et al.

  DOI：——

  日期：——