对甲基苯基对氯苯甲酰碲化物 | 251316-69-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 对甲基苯基对氯苯甲酰碲化物
• 英文名称: p-methylphenyl p-chlorobenzoyl telluride
• 英文别名: p-methylphenyl 4-chlorotellurobenzoate；Te-(4-methylphenyl) 4-chlorobenzenecarbotelluroate
• CAS: 251316-69-5
• 化学式: C₁₄H₁₁ClOTe
• 分子量: 358.294
• InChiKey: KTUPNVHVQTWVJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.82
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,6-二甲基苯基异腈 、 对甲基苯基对氯苯甲酰碲化物 以 氘代苯 为溶剂， 反应 6.0h， 以52%的产率得到p-methylphenyl N-(2,6-dimethylphenyl)-2-(4-chlorophenyl)-2-oxotelluro-acetoimidate
  参考文献：
  名称：

  酰基碲化物与异腈经自由基介导的基团转移亚胺基化反应合成α-酰基亚胺的新方法

  摘要：

  由酰基碲化物或烷基碲化物和一氧化碳产生的酰基与异腈反应生成α-酰基取代的亚氨基酰基碲化物，收率好至极好。在氧化条件下产物的水解提供相应的α-酰基酰胺。

  DOI：

  10.1016/s0040-4039(00)01287-9
• 作为产物：
  描述：

  4,4-二甲基二苯基二碲化物 、 alkaline earth salt of/the/ methylsulfuric acid 在 三氢化钐 、 氯化锆(IV) 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以90%的产率得到对甲基苯基对氯苯甲酰碲化物
  参考文献：
  名称：

  A NOVEL METHOD FOR THE SYNTHESIS OF TELLUROESTERS

  摘要：

  DOI：

  10.1080/00304949909355738

文献信息

• A new synthetic route to substituted quinones by radical-mediated coupling of organotellurium compounds with quinones
  作者：Shigeru Yamago、Masahiro Hashidume、Jun-ichi Yoshida

  DOI：10.1016/s0040-4020(02)00784-6

  日期：2002.8

  Carbon-centered radicals generated from the corresponding organotellurium compounds react with a variety of quinones under photo-thermal conditions to give the monoaddition product in moderate to excellent yield. The reaction can be used for the synthesis of polyprenyl quinoid natural products and C-glycosides.

  由相应的有机碲化合物产生的以碳为中心的自由基在光热条件下与各种醌反应，以中等至极好的收率得到单加成产物。该反应可用于合成聚异戊二烯基醌类天然产物和C-糖苷。
• Synthetic and Theoretical Studies on Group-Transfer Imidoylation of Organotellurium Compounds. Remarkable Reactivity of Isonitriles in Comparison with Carbon Monoxide in Radical-Mediated Reactions
  作者：Shigeru Yamago、Hiroshi Miyazoe、Ryuta Goto、Masahiro Hashidume、Takashi Sawazaki、Jun-ichi Yoshida

  DOI：10.1021/ja003879r

  日期：2001.4.1

  Imidoylation of organotellurium compounds with isonitriles has been investigated in conjunction with the radical-mediated C1 homologation reaction by using CO and isonitriles. Carbon-centered radicals generated photochemically or thermally from organotellurium compounds react with isonitriles in a group-transfer manner to give the corresponding imidoylated products. Organotellurium compounds have been found to serve as effective precursors of a wide variety of stabilized radicals, namely benzyl, alpha -alkoxy, alpha -amino, and acyl radicals, which take part in the imidoylation with high efficiency. The reactions are compatible with various functional groups, and can be carried out in various solvents including environmentally benign water. The reactivity of isonitriles has been compared with that of CO through competition experiments, and the results indicate that isonitriles are superior to CO as radical accepters in reactions with stabilized radicals. The origin of the differences has been addressed in theoretical studies with density functional theory calculations using the B3LYP hybrid functional. The calculations suggest that both carbonylation and imidoylation proceed with low activation energies, and that there an virtually no differences in the kinetic sense, instead, it indicates that thermodynamic effects, namely differences in the stability of the acyl and the imidoyl radicals, control the overall course of the reactions.