(R)-1-butyloxy-1-phenyl-ethane | 128732-40-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (R)-1-butyloxy-1-phenyl-ethane
• 英文别名: (R)-1-Butyloxy-1-phenyl-aethan；[(1R)-1-butoxyethyl]benzene
• CAS: 128732-40-1
• 化学式: C₁₂H₁₈O
• 分子量: 178.274
• InChiKey: AQGPVCBVZAHVBN-LLVKDONJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 (R)-1-butyloxy-1-phenyl-ethane
  参考文献：
  名称：

  52.一些瓦尔登翻转反应p甲苯磺酸和p的-toluenesulphinic酯升-phenylmethylcarbinol

  摘要：

  DOI：

  10.1039/jr9330000173

文献信息

• Carbohydrate base co-polymers as an efficient immobilization matrix to enhance lipase activity for potential biocatalytic applications
  作者：Kirtikumar Chandulal Badgujar、Bhalchandra Mahadeo Bhanage

  DOI：10.1016/j.carbpol.2015.08.036

  日期：2015.12

  In the present study, we have synthesized biocompatible hybrid blend of cellulosic polymers of hydroxypropyl-methyl-cellulose (HPMC) and chitosan (CHY) for the immobilization of Candida rugosa lipase (CRL). The immobilized biocatalyst HPMC:CHY:CRL was subjected for characterization such as SEM, TGA, water content analysis, lipase activity, specific activity and protein content analysis. The kinetic parameter study (R-max/K-m) demonstrated improved biocatalytic activity of lipase after immobilization on carbohydrate co-polymers of HPMC:CHY. This biocatalyst was then employed to study practical biocatalytic applications for kinetic resolution which provided 50% conversion and >94% enantiomeric excess of substrate/product (ees/eep). The protocol demonstrated excellent recyclability upto five cycles. Finally, we studied influence of immobilization on cellulosic polymers for substrate, structure and reactivity for kinetic resolution. Hence, we investigated R-0 (initial reaction rate), E-value (enantioselectivity) and E-a (activation energy). This study confirms that, lipase immobilized on carbohydrate polymers had 3-4 folds higher biocatalytic activity as compared to crude CRL. (C) 2015 Elsevier Ltd. All rights reserved.
• 52. Some Walden inversion reactions of the p-toluenesulphonic and p-toluenesulphinic esters of l-phenylmethylcarbinol
  作者：Joseph Kenyon、Henry Phillips、Frank M. H. Taylor

  DOI：10.1039/jr9330000173

  日期：——