N-(5-((1H-1,2,4-triazol-1-yl)methyl)-4-(tert-butyl)thiazol-2-yl)-1-(3,4-dimethylphenyl)methanimine | 1227256-09-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-(5-((1H-1,2,4-triazol-1-yl)methyl)-4-(tert-butyl)thiazol-2-yl)-1-(3,4-dimethylphenyl)methanimine
• CAS: 1227256-09-8
• 化学式: C₁₉H₂₃N₅S
• 分子量: 353.491
• InChiKey: SEPXDCKIIUNBGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.45
• 重原子数：
  25.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  55.96
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  3,4-二甲基苯甲醛 、 5-((1H-1,2,4-triazol-1-yl)methyl)-4-tert-butyl-1,3-thiazol-2-amine 在 哌啶 作用下， 以 甲苯 为溶剂， 反应 20.0h， 以35%的产率得到N-(5-((1H-1,2,4-triazol-1-yl)methyl)-4-(tert-butyl)thiazol-2-yl)-1-(3,4-dimethylphenyl)methanimine
  参考文献：
  名称：

  Synthesis and plant-growth regulatory activities of novel imine derivatives containing 1H-1,2,4-triazole and thiazole rings

  摘要：

  Eleven new imine derivatives 6 containing 1H-1,2,4-triazole and thiazole rings were synthesized by the condensation of 5-((1H-1,2,4-triazol-1-yl)methyl)-4-tert-butylthiazol-2-amine with various substituted benzaldehydes. The structures of the title compounds were characterized by H-1 NMR, MS and elemental analysis. The plant-growth regulatory activities of these compounds were evaluated. The primary bioassay results indicated that these target compounds exhibited promising plant-growth regulatory activities. (C) 2009 Jian Xin Fang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2009.11.007