2-oxo-2-phenylethyl 2-benzoylaminobenzoate | 307330-37-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-oxo-2-phenylethyl 2-benzoylaminobenzoate
• 英文别名: 2-Oxo-2-phenylethyl 2-(benzoylamino)benzoate；phenacyl 2-benzamidobenzoate
• CAS: 307330-37-6
• 化学式: C₂₂H₁₇NO₄
• 分子量: 359.381
• InChiKey: PZXLTKFVFCOQAV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  72.5
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-oxo-2-phenylethyl 2-benzoylaminobenzoate 在 乙酸铵 、 溶剂黄146 作用下， 反应 2.0h， 以33%的产率得到2.5-diphenylimidazol[1,2-c]quinazoline
  参考文献：
  名称：

  The Study of Cyclization of N-Acylphenacyl Anthranilates with Ammonium Salts under Various Conditions

  摘要：

  N-Acylphenacyl anthranilates were heated with ammonium salts in organic acid or NMP, and formation of various heterocyclic compounds was observed. Reaction results are strongly influenced by reaction conditions. The most interesting are imidazole derivatives with various anelated rings.

  DOI：

  10.3987/com-06-10899
• 作为产物：
  描述：

  2-氨基-2-氧代-2-苯基苯甲酸乙酯 、 苯甲酰氯 在 三乙胺 作用下， 以 丙酮 为溶剂， 反应 1.0h， 以84%的产率得到2-oxo-2-phenylethyl 2-benzoylaminobenzoate
  参考文献：
  名称：

  The Study of Cyclization of N-Acylphenacyl Anthranilates with Ammonium Salts under Various Conditions

  摘要：

  N-Acylphenacyl anthranilates were heated with ammonium salts in organic acid or NMP, and formation of various heterocyclic compounds was observed. Reaction results are strongly influenced by reaction conditions. The most interesting are imidazole derivatives with various anelated rings.

  DOI：

  10.3987/com-06-10899

文献信息

• The Study of Cyclization of N-Acylphenacyl Anthranilates with Ammonium Salts under Various Conditions
  作者：Pavel Hradil、Martin Grepl、Jan Hlavac、Antonin Lycka

  DOI：10.3987/com-06-10899

  日期：——

  N-Acylphenacyl anthranilates were heated with ammonium salts in organic acid or NMP, and formation of various heterocyclic compounds was observed. Reaction results are strongly influenced by reaction conditions. The most interesting are imidazole derivatives with various anelated rings.