(Z)-Dec-2-ene-4,6,8-triynoic acid methyl ester | 2739-57-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-Dec-2-ene-4,6,8-triynoic acid methyl ester
• 英文别名: cis-dehydromatricaria ester；cis-Dehydro-matricariasaeure-methylester；2-Decene-4,6,8-triynoic acid, methyl ester, (Z)-；methyl (Z)-dec-2-en-4,6,8-triynoate
• CAS: 2739-57-3
• 化学式: C₁₁H₈O₂
• 分子量: 172.183
• InChiKey: LBAVIXQTLKRIGP-KTKRTIGZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (Z)-Dec-2-ene-4,6,8-triynoic acid methyl ester 以 丙酮 为溶剂， 反应 1.0h， 以36.4%的产率得到反式-去氢母菊酯
  参考文献：
  名称：

  Light-activated plant growth inhibitory activity of cis-dehydromatricaria ester, rose bengal and fluoren-9-one on lettuce (Lactuca saliva L.)

  摘要：

  The polyacetylene allelopathic compound cis-dehydromatricaria ester (cis-DME) was extracted from the roots of goldenrod, Solidago altissima L. cis-DME strongly inhibited the growth of lettuce (Lactuca sativa L. c. v. sacramento) on its radicles and hypocotyls in the presence of light whereas less or no significantly different effects were observed in the dark The light-activated plant growth inhibitory (PGI) activity of cis-DME was more obvious in lettuce hypocotyls than in radicals. Its PGI activity was compared with the known phototoxic compounds rose bengal and fluoren-9-one. Although the light-activated PGI of cis-DME was not as high as that of rose bengal, and the dose-response relationship was slightly different with those of rose bengal and fluoren-9-one, cis-DME showed a very typical pattern of light-enhanced PGI activity against lettuce seedlings. The inhibition on the growth of lettuce radicles and hypocotyls highly enhanced by the presence of light A growth enhancement effect was also observed on the radicles of lettuce when treated with lower concentrations of fluoren-9-one. A photosensitization mechanism is proposed here that the PGI activity of cis-DME may involve photosensitization and active oxygen such as singlet oxygen. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0045-6535(96)00042-2
• 作为产物：
  描述：

  重氮甲烷 、 cis-Dec-2-en-4,6,8-triin-1-saeure 在 乙醚 作用下， 生成 (Z)-Dec-2-ene-4,6,8-triynoic acid methyl ester
  参考文献：
  名称：

  Bell et al., Journal of the Chemical Society, 1958, p. 1313,1320

  摘要：

  DOI：

文献信息

• BIOMARKERS FOR MALARIA DIAGNOSIS
  申请人：The United States of America, as represented by the Secretary, Dept. of Health and Human Services

  公开号：US20180052161A1

  公开（公告）日：2018-02-22

  Disclosed herein are methods of detecting Plasmodium in a subject (for example, presence of Plasmodium parasite) by detecting the presence and/or amount of one or more metabolites in a sample from the subject. In some embodiments, the methods include detecting in the sample one or more metabolites listed in Table 1, Table 2, and/or Tables 5-8. The amount of the one or more metabolites in the sample is compared to the amount of the one or more metabolites in a control and presence of Plasmodium is determined if the amount of the one or more metabolites is different (for example statistically significantly increased or decreased) compared to the control.
• [EN] BIOMARKERS FOR MALARIA DIAGNOSIS<br/>[FR] BIOMARQUEURS POUR LE DIAGNOSTIC DU PALUDISME
  申请人：THE US SECRETARY DEPT OF HEALTH & HUMAN SERVICES

  公开号：WO2016149386A1

  公开（公告）日：2016-09-22

  Disclosed herein are methods of detecting Plasmodium in a subject (for example, presence of Plasmodium parasite) by detecting the presence and/or amount of one or more metabolites in a sample from the subject. In some embodiments, the methods include detecting in the sample one or more metabolites listed in Table 1, Table 2, and/or Tables 5-8. The amount of the one or more metabolites in the sample is compared to the amount of the one or more metabolites in a control and presence of Plasmodium is determined if the amount of the one or more metabolites is different (for example statistically significantly increased or decreased) compared to the control.