Methyl-3-hydroxy-5-hexen-2-carbonsaeure-δ-lacton | 3780-64-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: Methyl-3-hydroxy-5-hexen-2-carbonsaeure-δ-lacton
• 英文别名: β-Methyl-Δ^α.β-δ-hexenolacton；4,6-dimethyl-5,6-dihydro-pyran-2-one；(+/-)-4,6-Dimethyl-5,6-dihydro-pyran-2-on；4,6-dimethyl-5,6-dihydro-2H-pyran-2-one；2,4-dimethyl-2,3-dihydropyran-6-one
• CAS: 3780-64-1
• 化学式: C₇H₁₀O₂
• 分子量: 126.155
• InChiKey: HAQPDUQSMQJVEE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,4-二甲基-2,5-二氢吡喃-6-酮 在 potassium carbonate 作用下， 生成 Methyl-3-hydroxy-5-hexen-2-carbonsaeure-δ-lacton
  参考文献：
  名称：

  The Reaction of Ketene with Unsaturated Ketones

  摘要：

  DOI：

  10.1021/ja01172a058

文献信息

• Korte; Machleidt, Chemische Berichte, 1955, vol. 88, p. 136,142
  作者：Korte、Machleidt

  DOI：——

  日期：——
• METHOD FOR PRODUCING 3,5-DIMETHYLDODECANOIC ACID; AND 4-CARBOXY-3,5-DIMETHYL-3,5-DODECADIENOIC ACID
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US20150344395A1

  公开（公告）日：2015-12-03

  Provided is a process for producing 3,5-dimethyldodecanoic acid, which is an active ingredient of the pheromone of California prionus, and 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid which is an intermediate useful for producing 3,5-dimethyldodecanoic acid. More specifically, provided is a method for producing 3,5-dimethyldodecanoic acid, comprising the steps of subjecting 3-methyl-2-pentene-1,5-diacid diester (1) and 2-nonanone (2) to a condensation reaction and subsequent hydrolysis into 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid (3); decarboxylating or decarboxylating and hydrolyzing the 4-carboxy-3,5-dimethyl-3,5-dodecadienoic acid (3) into 3,5-dimethyl-2,4-dodecadienoic acid (4); and hydrogenating the 3,5-dimethyl-2,4-dodecadienoic acid (4) into 3,5-dimethyldodecanoic acid (5), as shown in the following scheme:
• US9278899B2
  申请人：——

  公开号：US9278899B2

  公开（公告）日：2016-03-08
• The Reaction of Ketene with Unsaturated Ketones
  作者：Frank G. Young

  DOI：10.1021/ja01172a058

  日期：1949.4