2--aminoethanol | 26565-31-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2--aminoethanol
• 英文别名: N,N-Diaethyl-N'-methyl-N'-(2-hydroxy-aethyl)-aethylendiamin；2-[[2-(Diethylamino)ethyl]methylamino]ethanol；2-[2-(diethylamino)ethyl-methylamino]ethanol
• CAS: 26565-31-1
• 化学式: C₉H₂₂N₂O
• 分子量: 174.286
• InChiKey: MHAIOPHLDNBTJQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2--aminoethanol 、 丙烯酸甲酯（MA） 在 tetrabutoxytitanium 、 吩噻嗪 作用下， 生成 Acrylic acid 2-[(2-diethylamino-ethyl)-methyl-amino]-ethyl ester
  参考文献：
  名称：

  Korshunov,M.A. et al., Journal of Organic Chemistry USSR (English Translation), 1969, vol. 5, # 11, p. 1893 - 1898

  摘要：

  DOI：
• 作为产物：
  描述：

  N-甲基-2-羟基乙胺 、 N,N-二乙基氯乙胺 在 sodium hydroxide 作用下， 生成 2--aminoethanol
  参考文献：
  名称：

  Korshunov,M.A. et al., Journal of Organic Chemistry USSR (English Translation), 1969, vol. 5, # 11, p. 1893 - 1898

  摘要：

  DOI：

文献信息

• C-4" POSITION SUBSTITUTED MACROLIDE DERIVATIVE
  申请人：Sugimoto Tomohiro

  公开号：US20140046043A1

  公开（公告）日：2014-02-13

  A macrolide compound represented by the formula (I) effective against erythromycin resistant bacteria (for example, resistant pneumococci, streptococci and mycoplasmas).

  一种大环内酯化合物，化学式为（I），对红霉素耐药的细菌有效（例如，耐药的肺炎球菌，链球菌和支原体）。
• AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND AND POLYISOCYANATE ADHESIVE COMPOSITION CONTAINING AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND
  申请人：Tosoh Corporation

  公开号：EP2878609A1

  公开（公告）日：2015-06-03

  To provide an amine catalyst for curing a polyisocyanate which can satisfy both initial moldability before a thermal compression step and high reactivity at the time of thermal compression molding, and an adhesive composition containing it. A catalyst comprising an amine compound (1) represented by the formula (1) and an amine compound (2) represented by the formula (2) is used as an amine catalyst for curing a polyisocyanate compound. wherein each of R1 and R2 which are independent of each other, is a C1-4 hydrocarbon group, and R3 is a C1-4 hydrocarbon group having a hydroxy group or an amino group; wherein each of R4 and R5 which are independent of each other, is a C1-4 hydrocarbon group, R6 is a C1-4 hydrocarbon group or a C1-4 hydrocarbon group having a hydroxy group or an amino group, R7 is a C1-4 hydrocarbon group having a hydroxy group or an amino group, and m is an integer of from 2 to 6.

  目的 提供一种用于固化多异氰酸酯的胺催化剂，该催化剂既能满足热压步骤前的初始模 塑性，又能满足热压成型时的高反应活性，并提供一种含有该催化剂的粘合剂组合物。 由式（1）表示的胺化合物（1）和式（2）表示的胺化合物（2）组成的催化剂用作固化多异氰酸酯化合物的胺催化剂。 其中相互独立的 R1 和 R2 均为 C1-4 烃基，R3 为具有羟基或氨基的 C1-4 烃基； 其中相互独立的R4和R5各自是C1-4烃基，R6是C1-4烃基或具有羟基或氨基的C1-4烃基，R7是具有羟基或氨基的C1-4烃基，m是2至6的整数。
• COMPOUND, SALT THEREOF AND LIPID PARTICLES
  申请人：FUJIFILM Corporation

  公开号：EP3805198A1

  公开（公告）日：2021-04-14

  An object of the present invention is to provide a compound or a salt thereof constituting lipid particles that can achieve a high nucleic acid encapsulation rate and excellent delivery of nucleic acids, and to provide lipid particles that can achieve a high nucleic acid encapsulation rate and excellent delivery of nucleic acids. According to an aspect of the present invention, a compound represented by Formula (1) or a salt thereof is provided. In the formula, X represents -NR1- or -O-, R1 represents a hydrogen atom, a hydrocarbon group, or the like, R2 and R3 each independently represent a hydrogen atom, a hydrocarbon group, or the like, R4, R5, R6, R7, R8, R9, R10, R11, and R12 each independently represent a hydrogen atom or an alkyl group, groups in any one or more pairs among R4 and R5, R10 and R5, R5 and R12, R4 and R6, R5 and R6, R6 and R7, R6 and R10, R12 and R7, and R7 and R8 may be linked to each other to form a 4- to 7-membered ring which may contain an O atom, a, b, c, and d are each independently represent an integer of 0 to 3, a + b is equal to or greater than 1, and c + d is equal to or greater than 1.

  本发明的目的是提供一种化合物或其盐类构成的脂质微粒，该脂质微粒可实现较高的核酸包封率和核酸的良好递送，并提供可实现较高的核酸包封率和核酸的良好递送的脂质微粒。根据本发明的一个方面，提供了一种由式（1）代表的化合物或其盐。 式中，X代表-NR1-或-O-，R1代表氢原子、烃基或类似物，R2和R3各自独立地代表氢原子、烃基或类似物，R4、R5、R6、R7、R8、R9、R10、R11和R12各自独立地代表氢原子或烷基、R4和R5之间任意一对或多对的基团、R10 和 R5、R5 和 R12、R4 和 R6、R5 和 R6、R6 和 R7、R6 和 R10、R12 和 R7 以及 R7 和 R8 中的任意一对或多对基团可彼此相连，形成可包含 O 原子的 4 至 7 元环，a、b、c 和 d 各自独立地代表 0 至 3 的整数，a + b 等于或大于 1，c + d 等于或大于 1。
• Delayed action gelling catalyst compositions and methods for making polyurethane polymers
  申请人：EVONIK DEGUSSA GMBH

  公开号：US10081700B2

  公开（公告）日：2018-09-25

  Additives for making polyurethanes are disclosed. The additives are based on combining specific carboxylic acids or carboxylic di-acids together with a gelling catalysts obtained when mixing an isocyanate-reactive tertiary amine catalysts with dimethyl tin di carboxylate salts and/or dimethyltin mercaptide salts.

  本发明公开了用于制造聚氨酯的添加剂。这些添加剂的基础是将特定的羧酸或羧基二酸与异氰酸酯反应型叔胺催化剂和二甲基锡二羧酸盐和/或二甲基硫醇锡盐混合后得到的胶凝催化剂结合在一起。
• FUSED PYRIMIDINE COMPOUND, AND PREPARATION METHOD, INTERMEDIATE, COMPOSITION AND USES THEREOF
  申请人：Shanghai Yingli Pharmaceutical Co. Ltd.

  公开号：EP2860181B1

  公开（公告）日：2019-02-13