(E)-N-[(E)-benzylideneamino]-1-diphenylphosphanyl-3,3-dimethylbutan-2-imine | 144091-91-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-N-[(E)-benzylideneamino]-1-diphenylphosphanyl-3,3-dimethylbutan-2-imine
• CAS: 144091-91-8
• 化学式: C₂₅H₂₇N₂P
• 分子量: 386.477
• InChiKey: ZQVIOQQJRSMXRQ-LEXLDCMNSA-N

物化性质

• 沸点：
  507.0±52.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  24.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (E)-N-[(E)-benzylideneamino]-1-diphenylphosphanyl-3,3-dimethylbutan-2-imine 在 CO 作用下， 以 氘代苯 、 苯 为溶剂， 生成
  参考文献：
  名称：

  Complexes of the bidentate ligands PPh₂CH₂C(Bu^t)NNR₂(R = H or Me) and PPh₂CH₂C(Bu^t)N–NCHPh with palladium and platinum. X-Ray crystal structure of cis-[Pt{PPh₂CH₂C(Bu^t)NNH}₂]

  摘要：

  tert-Butyl diphenylphosphinomethyl ketone dimethylhydrazone L1 reacts with [PtCl2(cod)] (cod = cycloocta-1,5-diene) to give the chelate [PtCl2{PPh2CH2C(Bu(t))=NNMe2}] with a six-membered chelate ring; the corresponding palladium complex was also prepared. The phosphino dimethylhydrazone L1 or the phosphino hydrazone L2 also react with [PtMe2(cod)] to give (PtMe2{PPh2CH2C(But)=NNR2}], (R = Me or H); these platinum(II) complexes react with methyl iodide to give the corresponding trimethylplatinum(IV) complexes [PtMe3I{PPh2CH2C(But)=NNR2}]. Treatment of [PtCl2(cod)] with 2 equivalents of L2 gave the dication cis-[Pt{PPh2CH2C(But)=NNH2}2]2+ isolated as the chloride or chloride hexafluorophosphate salts. The dicationic dichloride reacted with 2 moles of sodium ethoxide to give the neutral cis-[Pt{PPhCH2C(But)=NNH}2]. Treatment of [PdCl2(NCPh)2] with L2 gave [Pd{PPh2CH2C(But)=NNH2}2]Cl2, which with sodium ethoxide gave the neutral trans[Pd{PPh2CH2C(But)=NNH}2]. The mixed azine monophosphine PPh2CH2C(But)=N-N=CHPh L3 with [PdCl2(NCPh)2] gave the chelate complex [PdCl2{PPh2CH2C(But)=N-N=CHPh}] and with [PtMe2(cod)] it gave [PtMe2{PPh2CH2C(But)=N-N=CHPh)]. Treatment of [PtCl2(NCMe)2] with 2 equivalents of L3 gave trans-[PtCl2{PPh2CH2C(But)=N-N=CHPh}2] which on heating gave the dicationic dichloride salt cis-[Pt{PPh2CH2C(But)=N-N=CHPh}2]Cl2. Successive treatments of this salt with 1 mole of sodium methoxide gave cis-[{PPh2CH2C(But)=N-N=CHPh}Pt{PPh2CH=C(But)N-N=CHPh}]+ and cis-[Pt{PPh2CH=C(But)N-N=CHPh}2]. Proton, C-13-{H-1}, P-31-{H-1) NMR and infrared data have been obtained. Crystals of cis-[Pt{PPh2CH2C(But)=NNH2}2 are monoclinic, space group P2(1)/c, with a = 1261.5(2), b = 1794.6(3), c = 1792.0(4) pm and Z = 4; final R = 0.0451 for 4088 observed reflections.

  DOI：

  10.1039/dt9940000103
• 作为产物：
  描述：

  (Z)-1-diphenylphosphanyl-N-[(Z)-(1-diphenylphosphanyl-3,3-dimethylbutan-2-ylidene)amino]-3,3-dimethylbutan-2-imine 在 一水合肼 、 溶剂黄146 作用下， 以 异丙醇 、 苯 为溶剂， 反应 16.5h， 生成 (E)-N-[(E)-benzylideneamino]-1-diphenylphosphanyl-3,3-dimethylbutan-2-imine
  参考文献：
  名称：

  新的双齿配体PPh 2 CH 2 C（Bu t）NNR 2（R = H或Me）和PPh 2 CH 2 C（Bu t）NNCHPh及其与6族金属羰基化合物的配合物

  摘要：

  的治疗叔丁基甲基酮二甲基腙与礼部，接着PPH 2氯，得到结晶膦二甲基腙PPH 2 CH 2 C（卜吨）NNMe 2 2a中具有与c NNMe 2中的组Ž配置。该具有[Mo（CO）4（nbd）]（nbd =降冰片二烯）的膦得到的[Me 2 }] 3a具有六元螯合环。相应地制备了相应的钨3b和铬3c配合物。当将膦2a与[Mo（CO）[图6 ]与同分异构体[NMe 2 }] 4一起形成了一些3a，其中五元螯合环和围绕CNNMe 2的E排列。当在二甘醇二甲醚[MeO（CH 2） 2 O（CH 2） 2 OMe]中加热3a时，温度约为。在150℃下形成膦亚胺络合物[H]] 5。带有肼的化合物2a以超过90％的产率得到了含有CNNH 2部分的相应的膦2c。膦2a或2c与硫反应，得到相应的膦硫化物。具有[M（CO）4（nbd）]的膦2c给出[[未图示] H 2 }]（M ＝ Mo 3d，W 3e或Cr

  DOI：

  10.1039/dt9920002361

文献信息

• Cyclometallation of azine phosphines of type Z,E-PPh₂CH₂C(Bu^t)N–NCHR (R = an aromatic or heterocyclic group) involving X–Y (X = C, N or O; Y = H, I or Br) bond fission by platinum(<scp>II</scp>)
  作者：Sarath D. Perera、Bernard L. Shaw

  DOI：10.1039/dt9950000641

  日期：——

  converting aryl or heterocyclic aldehydes into azines which can then be cycloplatinated readily with C–H, C–I, C–Br, N–H or O–H bond fission. Condensation of 1 with benzaldehyde derivatives (RCHO) gave mixed azines of type Z,E-PPh2CH2C(But)N–NCHR [R = Ph 2a, C6H2(OMe)3-3,4,5 2b, C6H4NO2-4 2c, C6H4I-2 2d, C6H4Br-2 2e, C6H4Cl-2 2f or C6H2(OH-2)(OMe)2-4,6 2g]. The azines 2a–2f reacted with [PtMe2(cod)](cod = cycloocta-1

  膦Z -PPh 2 CH 2 C（Bu t）NNH 2 1被证明是一种方便的“试剂”，用于将芳基或杂环醛转化为嗪，然后可以容易地用C–H，C–I，C进行环铂化-Br，NH或OH键裂变。1与苯甲醛衍生物（RCHO）缩合得到Z型，E -PPh 2 CH 2 C（Bu t）N–N CHR [R = Ph 2a，C 6 H 2（OMe）3 -3,4， 5 2b，C6 ħ 4 NO 2 -4 2C，C 6 H ^ 4 I-2 2d中，C 6 H ^ 4 BR-2 2E，C 6 H ^ 4 CL-2 2F或C 6 H ^ 2（OH-2）（OME） 2 - 4,6 2克]。嗪2a - 2f在20°C下与[PtMe 2（cod）]（cod =环辛-1,5-二烯）反应，得到二甲基铂（ II）配合物[[图略]CHR}] 3a - 3f分别含有六元螯合环。用[PtMe 2（cod）]处理2g，会发生O-H键裂变
• General strategy for inducing C–H bond fission (cycloiridation) in some aryl, heterocyclic, alkenyl or alkyl groups in azines derived from aldehydes or methyl ketones
  作者：Sarath D. Perera、Bernard L. Shaw、Mark Thornton-Pett

  DOI：10.1039/dt9950001689

  日期：——

  [IrCl(CO)2(H2NC6H4Me-p)] in benzene at 75 °C for 5 min it underwent an aryl C–H bond fission to give the cyclometallated chlorocarbonyliridium(III) hydride [[graphic omitted]H(OMe)3-3,4,5]}]1a. The crystal structure of 1a showed that (i) oxidative addition of the aryl C–H bond to iridium was cis with the hydride ligand trans to chloride, and (II) the cyclometallated azine ligand was in the terdentate mer

  膦Z -PPh 2 CH 2 C（Bu t）NNH 2 I已被证明是一种方便的“试剂”，用于将醛或酮转化为嗪，然后可以通过CH键裂变快速环化以生成铱（III）氢化物。的缩合我与一系列取代的苯甲醛的（RCHO），得到类型的混合吖嗪Ž，ë -PPh 2 CH 2 C（卜吨）N-N CHR [R = C 6 H ^ 2（OME）3 -3,4， 5 IIA，博士IIb，C 6 H 4 OMe-4 IIc，C 6 H 4 NO 2 -4 IId，C 6 H 4 Br-2 IIe，C 6 H 4 Cl-2 IIf，C 6 H 4 F-2 IIg，C 6 H 4 OH-2 IIh或C 6 H 2（OH-2）（OMe）2 -4,6，IIi ]。该ž，ē构型对于随后的环金属化是必要的，并且当将嗪IIa在苯中于75°C下用[IrCl（CO）2（H 2 NC 6 H 4 Me- p）]处理5分钟时，它会发生芳基
• A general method of promoting oxidative addition of C–H bonds to iridium(<scp>I</scp>) using azine phosphines
  作者：Sarath D. Perera、Bernard L. Shaw

  DOI：10.1039/c39940001203

  日期：——

  Treatment of [IrCl(CO)2(p-toludine)] with azine phosphines of type Z,E-PPh2CH2C(But)N–NC(Q)R, Q = H or Me, R = an organic group, activates aryl, heterocyclic, alkenyl or aliphatic C–H bonds to give cyclometallated iridium(III) hydrides.

  用 Z,E-PPh2CH2C(But)N−NC(Q)R 型吖嗪膦处理 [IrCl(CO)2(p-toludine)]，Q = H 或 Me，R = 有机基团，活化芳基、杂环、烯基或脂肪族C-H键，得到环金属化铱(III)氢化物。