(E)-3-(3-methoxyphenyl)-2-nitroprop-2-enenitrile | 448897-29-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (E)-3-(3-methoxyphenyl)-2-nitroprop-2-enenitrile
• CAS: 448897-29-8
• 化学式: C₁₀H₈N₂O₃
• 分子量: 204.185
• InChiKey: WCMJMKCNFRSFCR-WEVVVXLNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  78.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (E)-3-(3-methoxyphenyl)-2-nitroprop-2-enenitrile 、 5,5-二甲基-1,3-环己二酮 以52%的产率得到
  参考文献：
  名称：

  METCHKOV T. D.; DEMIREVA Z. I.; PANAYOTOVA T. V., DOKL. BOLG. AN, 39,(1986) N 6, 51-53

  摘要：

  DOI：
• 作为产物：
  描述：

  3-甲氧基苯甲醛 生成 (E)-3-(3-methoxyphenyl)-2-nitroprop-2-enenitrile
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Effect of Microwave Irradiation on Reaction of Arylaldehyde Derivatives with Some Active Methylene Compounds in Aqueous Media
  作者：Hassan Valizadeh、Manouchehr Mamaghani、Abed Badrian

  DOI：10.1081/scc-200050942

  日期：2005.3

  The effect of microwave irradiation on the condensation reactions of arylaldehydes 1 and active methylene compounds 2 in aqueous media was studied and compared with "classical" conditions. The results show that the condensation was carried out only under microwave irradiation in the presence of ammonium chloride as a catalyst, followed by dehydration, to afford (E)-olefins 3. The protocol was used to synthesize coumarins by a condensation reaction of salicylaldehyde or its derivatives with various derivatives of ethylacetate 5 (e.g., (RCH2CO2Et)-C-3; R-3: CO2Et, CO2Me, COMe, CN) in high yields. These investigations will contribute to the development of environmentally friendly and inexpensive processes in organic synthesis.
• Heterocycles with a β-nitroenamine fragment
  作者：V. P. Kislyi、V. N. Nesterov、A. M. Shestopalov、V. V. Senfenov

  DOI：10.1007/bf02496016

  日期：1999.6

  The reactions of 4-hydroxy-6-methyl-2-pyrone and 4-hydroxycoumarin with arylidenenitroacetonitriles result in 2-amino-3-nitropyrano[3,2-c]pyrans and 2-amino-3-nitropyrano[3,2-c]chromenes, respectively. The crystal and molecular structure of one of the compounds obtained was determined by X-ray diffraction analysis.
• METCHKOV, T.;DEMIREVA, L., Z. CHEM., 1985, 25, N 5, 169-170
  作者：METCHKOV, T.、DEMIREVA, L.

  DOI：——

  日期：——
• METCHKOV T. D.; DEMIREVA Z. I.; PANAYOTOVA T. V., DOKL. BOLG. AN, 39,(1986) N 6, 51-53
  作者：METCHKOV T. D.、 DEMIREVA Z. I.、 PANAYOTOVA T. V.

  DOI：——

  日期：——
• ——
  作者：MECHKOV TS. D.、 TONCHEVA E. K.、 DEMIREVA Z. I.

  DOI：——

  日期：——