5-乙炔-1,3-苯二醇 | 145078-84-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 5-乙炔-1,3-苯二醇
• 英文名称: 1-ethynyl-3,5-dihydroxybenzene
• 英文别名: 5-Ethynylbenzene-1,3-diol
• CAS: 145078-84-8
• 化学式: C₈H₆O₂
• mdl: MFCD02181104
• 分子量: 134.134
• InChiKey: IBVOCRDZMOXCHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-乙炔-1,3-苯二醇 在 copper(ll) sulfate pentahydrate 、 碳酸氢钠 、 potassium carbonate 、 sodium ascorbate 、 间氯过氧苯甲酸 作用下， 以 四氢呋喃 、 二氯甲烷 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 4.25h， 生成 tert-butyl (Z)-(4-((3-((4-(3,5-bis(pent-4-yn-1-yloxy)phenyl)-1H-1,2,3-triazol-1-yl)methyl)phenyl)sulfonyl)-3-fluorobut-2-en-1-yl)carbamate
  参考文献：
  名称：

  [EN] BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF
  [FR] BIOSONDES POUR LYSYL OXYDASES ET LEURS UTILISATIONS

  摘要：

  本发明涉及能够结合特定胺氧化酶的新型生物探针。这些生物探针在检测和确定样本中特定胺氧化酶的浓度的方法中是有用的，同时也可用于定量评估特定胺氧化酶的抑制方法。

  公开号：

  WO2021155439A1
• 作为产物：
  描述：

  3,5-二羟基苯甲醛 在 4-二甲氨基吡啶 、 硫酸 、 三乙胺 、 三苯基膦 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 甲醇 、 正己烷 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 83.17h， 生成 5-乙炔-1,3-苯二醇
  参考文献：
  名称：

  End-Cap Stabilized Oligoynes: Model Compounds for the Linear sp Carbon Allotrope Carbyne

  摘要：

  Three series of differently 3,5-disubstituted alpha,omega-diphenylpolyynes Ar-(CdropC)(n)-Ar (n=2, 4, 6, 8, 10) were synthesized under optimized Cadiot-Chodkiewicz conditions, isolated and completely characterized. These compounds can be considered as model substances for the hypothetical one-dimensional carbon allotrope carbyne C, The longest sp-carbon chain contains 20 atoms and is therefore the longest, purely organic polyyne studied with NMR techniques. Extinction coefficients over 600000m(-1)cm(-1) represent the highest measured quantitative values for that compound class so far. Comparisons with previous investigations and electrochemical studies allow the assignment of absorption for both wavelength regions structuring the UV/Vis spectra. Based on the trends in the spectroscopic behaviour of those molecules with increasing chain length. electronic as well as the NMR properties of carbyne are predicted, in line with our previously reported results. The observed stability mise the. properties pro synthesis of even longer polyynes.

  DOI：

  10.1002/1521-3765(20020118)8:2<408::aid-chem408>3.0.co;2-l

文献信息

• Synthesis and Electrochemical, Photophysical, and Self-Assembly Studies on Water-Soluble pH-Responsive Alkynylplatinum(II) Terpyridine Complexes
  作者：Clive Yik-Sham Chung、Steve Po-Yam Li、Kenneth Kam-Wing Lo、Vivian Wing-Wah Yam

  DOI：10.1021/acs.inorgchem.6b00513

  日期：2016.5.2

  A series of water-soluble pH-responsive alkynylplatinum(II) terpyridine complexes have been synthesized and characterized. The electronic absorption, emission, and electrochemical properties of the complexes have been studied. The self-assembly processes of representative complexes in aqueous media, presumably through Pt···Pt and/or π–π interactions, have been investigated by concentration- and temperature-dependent

  已合成和表征了一系列水溶性的pH响应性炔基铂（II）吡啶配合物。已经研究了配合物的电子吸收，发射和电化学性质。通过与浓度和温度相关的紫外可见吸收测量和动态光散射实验，研究了水性介质中代表性复合物的自组装过程，大概是通过Pt··Pt和/或π–π相互作用进行的。有趣的是，已经发现某些配合物通过调节溶液的pH值在水性介质中引起诱导的自组装和分解，从而导致显着的UV-vis吸收和发射光谱变化。配合物亲水性的变化使发射光谱的变化合理化，复合物分子之间的静电排斥，和/或复合物上pH响应基团的质子化/去质子化时，光诱导电子转移（PET）的猝灭程度。通过简单地改变配合物的化学结构，可以在不同和/或多个pH区域发生配合物的诱导自组装/分解，从而允许通过三重态金属-金属-金属间化合物探测所需pH区域的变化。配体在近红外（NIR）区域的配体电荷转移发射。固定细胞成像实验进一步证明了这类复合物作为体外pH响应NIR发光探针的潜力，
• Induced self-assembly and disassembly of water-soluble alkynylplatinum(ii) terpyridyl complexes with “switchable” near-infrared (NIR) emission modulated by metal–metal interactions over physiological pH: demonstration of pH-responsive NIR luminescent probes in cell-imaging studies
  作者：Clive Yik-Sham Chung、Steve Po-Yam Li、Man-Wai Louie、Kenneth Kam-Wing Lo、Vivian Wing-Wah Yam

  DOI：10.1039/c3sc50196e

  日期：——

  Water-soluble alkynylplatinum(II) terpyridine complexes, [Pttpy(C6H4CH2NMe3-4)-4′}(CC–Ar)](OTf)2 [Ar = C6H3–(OH)2-3,5 (1), C6H4OH-4 (2), C6H3–(OMe)2-3,5 (3)], have been synthesized and characterized. The photophysical and electrochemical properties of the complexes have been studied. Complex 1 has been found to undergo aggregation at low pHs, leading to metal–metal and/or π–π interactions and the emergence of a triplet metal-metal-to-ligand charge transfer (3MMLCT) emission in the near-infrared (NIR) region, the intensity of which has been enhanced 1350-fold over that at physiological pH. Such ‘switchable’ NIR emission of complex 1 was employed in cell-imaging experiments. The pH response of the 3MMLCT emission of complex 1 in cellular compartments has been studied using experiments with fixed Madin–Darby canine kidney (MDCK) cells, while live cell-imaging experiments revealed that complex 1 could function as a NIR luminescent probe for the tracking of the location of acidic organelles such as lysosomes.

  水溶性炔基铂(II)三联吡啶络合物，[Pttpy(C6H4CH2NMe3-4)-4â²}(CCâAr)](OTf)2 [Ar = C6H3â(OH)2-3,5 ( 1)、C6H4OH-4 (2)、C6H3·(OMe)2-3,5 (3)]已被合成并表征。研究了配合物的光物理和电化学性质。研究发现配合物 1 在低 pH 下会发生聚集，导致金属-金属和/或---相互作用，并在溶液中出现三重态金属-金属-配体电荷转移 (3MMLCT) 发射。近红外（NIR）区域，其强度比生理pH值增强1350倍。复合物 1 的这种“可切换”近红外发射被用于细胞成像实验。使用固定的 MadinäDarby 犬肾 (MDCK) 细胞进行实验，研究了细胞区室中复合物 1 的 3MMLCT 发射的 pH 响应，而活细胞成像实验表明，复合物 1 可以作为 NIR 发光探针，用于检测跟踪酸性细胞器（例如溶酶体）的位置。
• Desilylation Reactions of Poly[(<i>t</i>-butyldimethylsilyloxy)phenylacetylene]s
  作者：Masahiko Yamaguchi、Kenji Omata、Masahiro Hirama

  DOI：10.1246/cl.1992.2261

  日期：1992.11

  Poly[4-(t-butyldimethylsilyloxy)-2-trimethylsilylphenylacetylene] and poly[5-ethynyl-3-(t-butyldimethylsilyloxy)phenyl (R)-2-phenylpropionate] were desilylated with Bu4NF in THF. The solution changed its color depending on the structure of the aromatic pendants.

  将聚[4-(叔丁基二甲基甲硅烷氧基)-2-三甲基甲硅烷基苯乙炔]和聚[5-乙炔基-3-(叔丁基二甲基甲硅烷氧基)苯基(R)-2-苯基丙酸酯]用Bu4NF在THF中脱甲硅烷基化。该溶液根据芳香吊坠的结构改变颜色。
• AROMATIC HYDROCARBON-BASE PROTON EXCHANGE MEMBRANE AND DIRECT METHANOL FUEL CELL USING SAME
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP1826846A1

  公开（公告）日：2007-08-29

  A proton exchange membrane is obtained which can give an excellent power generation characteristic when the membrane is applied to, in particular, a fuel cell wherein high-concentration methanol is used as a fuel. In the aromatic hydrocarbon based proton exchange membrane of the invention, the ion exchange capacity is set into the range of 0.6 to 1.3 meq/g. Moreover, the area swelling rate for a 30% by mass methanol aqueous solution at 40°C is set into the range of 2 to 30%. Preferably, a sulfonic acid group is bonded to an aromatic ring of the aromatic hydrocarbon based polymer contained in the aromatic hydrocarbon based proton exchange film. Preferably, the aromatic hydrocarbon based polymer is a polyarylene ether based polymer.

  本发明获得了一种质子交换膜，当将该膜应用于燃料电池，特别是使用高浓度甲醇作为燃料的燃料电池时，该膜可提供出色的发电特性。在本发明的芳香烃基质子交换膜中，离子交换容量设定在 0.6 至 1.3 meq/g 的范围内。此外，在 40°C 时，质量分数为 30% 的甲醇水溶液的面积膨胀率设定为 2% 至 30%。优选地，磺酸基与芳香烃基质子交换膜中所含芳香烃基聚合物的芳香环键合。芳香烃基聚合物最好是聚芳醚基聚合物。
• SULFONIC ACID GROUP-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, RESIN COMPOSITION CONTAINING SUCH SULFONIC ACID GROUP-CONTAINING POLYMER, POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE/ELECTRODE ASSEMBLY, AND FUEL CELL
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP1889863A1

  公开（公告）日：2008-02-20

  The present invention relates to a sulfonic acid group-containing polymer excellent in ion conductivity and durability, a method for producing the same, a resin composition containing the sulfonic acid group-containing polymer, a polymer electrolyte membrane, a polymer electrolyte membrane/electrode assembly, and a fuel cell. The sulfonic acid group-containing polymer of the present invention, in a first embodiment, includes a constituent represented by the following chemical formula 1: wherein X represents hydrogen or a monovalent cation species; Y represents a sulfone group or a ketone group; and n represents an arbitrary integer not less than 2.

  本发明涉及一种离子传导性和耐久性极佳的含磺酸基聚合物、其生产方法、含有该含磺酸基聚合物的树脂组合物、聚合物电解质膜、聚合物电解质膜/电极组件和燃料电池。在第一个实施方案中，本发明的含磺酸基聚合物包括由以下化学式表示的成分 1： 其中 X 代表氢或一价阳离子种类；Y 代表砜基或酮基；n 代表不小于 2 的任意整数。