tris(2-carboxyethyl)phosphine oxide | 5962-40-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tris(2-carboxyethyl)phosphine oxide
• 英文别名: TCEPO；Tris(2-carboxyethyl)phosphinoxid；3,3',3''-Phosphoryltripropanoic acid；3-[bis(2-carboxyethyl)phosphoryl]propanoic acid
• CAS: 5962-40-3
• 化学式: C₉H₁₅O₇P
• 分子量: 266.188
• InChiKey: XJGZCDJZBUBTKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  17
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  129
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  tris(2-carboxyethyl)phosphine oxide 、 N,N-dinonyl-1,2-ethylenediamine 在 N,N-二异丙基乙胺 、 N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  LIPID COMPOUND OR A DERIVATIVE THEREOF AND PHARMACEUTICAL COMPOSITION EMPLOYING THE SAME

  摘要：

  本发明提供了一种脂质化合物及其衍生物，以及一种采用该化合物的药物组合物。所述脂质化合物具有由式(I)表示的结构：其中，Z1、Z2、Z3和Z4如说明书中所披露。

  公开号：

  EP4368626A1
• 作为产物：
  描述：

  三(2-氰乙基)膦 在 氢氧化钾 、 双氧水 、 sodium acetate 作用下， 生成 tris(2-carboxyethyl)phosphine oxide
  参考文献：
  名称：

  The Cyanoethylation of Phosphine and Phenylphosphine

  摘要：

  DOI：

  10.1021/ja01514a022

文献信息

• Tris(3-hydroxypropyl)phosphine (THPP): A mild, air-stable reagent for the rapid, reductive cleavage of small-molecule disulfides
  作者：James McNulty、Venkatesan Krishnamoorthy、Dino Amoroso、Michael Moser

  DOI：10.1016/j.bmcl.2015.08.027

  日期：2015.10

  Tris(3-hydroxypropyl)phosphine (THPP) is demonstrated to be a versatile, water-soluble and air-stable reducing agent, allowing for the rapid, irreversible reductive cleavage of disulfide bonds in both aqueous and buffered aqueous–organic media. The reagent shows exceptional stability at biological pH under which condition it permits the rapid reduction of a wide range of differentially functionalized

  三（3-羟丙基）膦（THPP）被证明是一种多功能，水溶性和空气稳定的还原剂，可在水性和缓冲水性有机介质中快速，不可逆地还原二硫键。该试剂在生物pH值下显示出优异的稳定性，在此条件下，该试剂可快速还原各种不同功能的小分子二硫化物。
• Clean Donor Oxidation Enhances the H ₂ Evolution Activity of a Carbon Quantum Dot–Molecular Catalyst Photosystem
  作者：Benjamin C. M. Martindale、Evelyne Joliat、Cyril Bachmann、Roger Alberto、Erwin Reisner

  DOI：10.1002/anie.201604355

  日期：2016.8

  Carbon quantum dots (CQDs) are new‐generation light absorbers for photocatalytic H2 evolution in aqueous solution, but the performance of CQD‐molecular catalyst systems is currently limited by the decomposition of the molecular component. Clean oxidation of the electron donor by donor recycling prevents the formation of destructive radical species and non‐innocent oxidation products. This approach

  碳量子点（CQDs）是用于光催化水溶液中H 2逸出的新一代光吸收剂，但是CQD分子催化剂体系的性能目前受到分子成分分解的限制。电子供体通过供体再循环而干净地氧化，可防止形成破坏性的自由基物质和非无害的氧化产物。这种方法使CQD分子双（二膦）镍镍光催化剂系统的基准寿命达到5天以上，并且纯合成分子镍催化剂的营业额达到创纪录的1094±61 mol H2  （mol Ni）-1。水溶液在AM1.5G日光照射下。
• FLUORESCENT ENTITY, DYEING COMPOSITION CONTAINING AT LEAST ONE FLUORESCENT ENTITY COMPRISING AT LEAST ONE HETEROCYCLE, WITH AT LEAST ONE INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID AT LEAST ONE FLUORESCENT ENTITY
  申请人：Greaves Andrew

  公开号：US20120031422A9

  公开（公告）日：2012-02-09

  The invention relates to a dyeing composition containing a thiol/disulphide fluorescent colorant comprising a heterocycle, and to a method for colouring keratin materials, especially keratin fibres, particularly human keratin fibres such as hair, with a lightening effect, using said composition. The invention also relates to novel thiol/disulphide fluorescent colorants and the uses thereof for lightening keratin materials. Said composition produces a lightening effect which is especially tenacious and visible on dark keratin fibres.

  本发明涉及一种含有硫醇/二硫化物荧光染料的染料组合物，该染料组合物包括一个杂环，并且涉及一种用该组合物对角蛋白质材料进行着色的方法，特别是对角蛋白质纤维，尤其是人类角蛋白质纤维（如头发），并产生一种光亮效果。该发明还涉及新的硫醇/二硫化物荧光染料及其在光亮角蛋白质材料中的应用。该组合物产生的光亮效果在深色角蛋白质纤维上尤为持久和明显。
• DYE COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT DYE COMPRISING AMINO GROUPS AND COMPRISING AN INTERNAL CATIONIC CHARGE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE
  申请人：Greaves Andrew

  公开号：US20100287714A1

  公开（公告）日：2010-11-18

  The invention relates to a dye composition comprising a thiol/disulphide fluorescent dye comprising amino groups, and to a dyeing process which has a lightening effect on keratin materials, in particular keratin fibres, especially human keratin fibres such as the hair, using said composition. It similarly relates to novel thiol/disulphide fluorescent dyes and to uses thereof in lightening keratin materials. This composition makes it possible to obtain a particularly resistant and visible lightening effect on dark keratin fibres.

  本发明涉及一种染料组合物，包括一种含有氨基的巯基/二硫键荧光染料，以及一种染色工艺，对角蛋白质材料，特别是角蛋白质纤维，尤其是人类角蛋白质纤维，如头发，使用该组合物具有美白效果。它同样涉及到新型的巯基/二硫键荧光染料及其在美白角蛋白质材料方面的应用。该组合物使得在黑色角蛋白质纤维上获得特别耐用和明显的美白效果成为可能。
• DYE COMPOSITION CONTAINING A THIOL/DISULPHIDE FLUORESCENT DYE COMPRISING A HETEROCYCLE,AND COMPRISING AN INTERNAL CATIONIC CHARGE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE
  申请人：Greaves Andrew

  公开号：US20110011417A1

  公开（公告）日：2011-01-20

  The invention relates to a dyeing composition containing a thiol/disulphide fluorescent colorant comprising a heterocycle, and to a method for colouring keratin materials, especially keratin fibres, particularly human keratin fibres such as hair, with a lightening effect, using said composition. The invention also relates to novel thiol/disulphide fluorescent colorants and the uses thereof for lightening keratin materials. Said composition produces a lightening effect which is especially tenacious and visible on dark keratin fibres.

  本发明涉及一种染料组合物，其包含一种含有硫醇/二硫键荧光颜料的杂环染料，并且涉及一种用该组合物为角蛋白材料（特别是角蛋白纤维，尤其是人类角蛋白纤维，如头发）着色的方法，具有变浅的效果。本发明还涉及新型硫醇/二硫键荧光颜料及其用于变浅角蛋白材料的用途。该组合物在深色角蛋白纤维上产生特别持久和明显的变浅效果。