4-methyl-2,2-diphenyl-valeric acid amide | 101718-01-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methyl-2,2-diphenyl-valeric acid amide
• 英文别名: 4-Methyl-2,2-diphenyl-valeriansaeure-amid；4-Methyl-2,2-diphenylpentanamide；4-methyl-2,2-diphenylpentanamide
• CAS: 101718-01-8
• 化学式: C₁₈H₂₁NO
• 分子量: 267.371
• InChiKey: ATNFHKALRHSKMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  戊腈,4-甲基-2-苯基-, 在 硫酸 、 溴 、 溶剂黄146 作用下， 生成 4-methyl-2,2-diphenyl-valeric acid amide
  参考文献：
  名称：

  Hoch; Lecocq, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1957, vol. 245, p. 73

  摘要：

  DOI：

文献信息

• [EN] HIGH SENSITIVITY MASS SPECTROMETRY SYSTEMS<br/>[FR] SYSTÈMES DE SPECTROMÉTRIE DE MASSE À HAUTE SENSIBILITÉ
  申请人：UNIV ILLINOIS STATE

  公开号：WO2012155090A2

  公开（公告）日：2012-11-15

  A high sensitivity desorption electrospray ionization mass spectrometry system that employs a heated platform, along with means for directing a liquid stream containing an analyte of interest onto a target location on the heated platform to heat the stream, an electrospray emitter for generating an electrospray and directing the electrospray at the target location on the heated platform to produce an ionized, desorbed analyte, and a mass spectrometer for receiving and detecting the ionized, desorbed analyte.
• [EN] COMPOSITIONS OF PHARMACEUTICAL ACTIVES CONTAINING DIETHYLENE GLYCOL MONOETHYL ETHER OR OTHER ALKYL DERIVATIVES<br/>[FR] COMPOSITIONS DE PRINCIPES PHARMACEUTIQUES ACTIFS CONTENANT DE L'ÉTHER DE MONOÉTHYLE ET DE DIÉTHYLÈNEGLYCOL OU D'AUTRES DÉRIVÉS ALKYLIQUES
  申请人：THEMIS MEDICARE LTD

  公开号：WO2014178065A1

  公开（公告）日：2014-11-06

  The present invention relates to pharmaceutical compositions of various pharmaceutical actives, especially lyophilic and hydrophilic actives containing Diethylene glycol monoethyl ether or other alkyl derivatives thereof as a primary vehicle and/or to pharmaceutical compositions utilizing Diethylene glycol monoethyl ether or other alkyl derivatives thereof as a primary vehicle or as a solvent system in preparation of such pharmaceutical compositions. The pharmaceutical compositions of the present invention are safe, non-toxic, exhibits enhanced physical stability compared to conventional formulations containing such pharmaceutical actives and are suitable for use as injectables for intravenous and intramuscular administration, as well as for use as a preformed solution/liquid for filling in and preparation of capsules, tablets, nasal sprays:; gargles, dermal applications, gels, topicals. liquid oral dosage forms and other dosage forms.
• [EN] PHARMACEUTICAL COMPOSITION WITH IONICALLY CROSSLINKED POLYMER ENCAPSULATION OF ACTIVE INGREDIENT<br/>[FR] COMPOSITION PHARMACEUTIQUE À ENCAPSULATION PAR POLYMÈRE IONIQUEMENT RÉTICULÉ DU PRINCIPE ACTIF
  申请人：ALLEN ERIC

  公开号：WO2015184317A1

  公开（公告）日：2015-12-03

  Compositions and thin films containing an encapsulated active pharmaceutical ingredient, as well as methods of manufacturing and using the same.
• Hoch; Lecocq, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1957, vol. 245, p. 73
  作者：Hoch、Lecocq

  DOI：——

  日期：——