2-十六烷基-1,4-二甲氧基苯 | 105349-23-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-十六烷基-1,4-二甲氧基苯
• 英文名称: 2-hexadecyl-1,4-dimethoxy-benzene
• 英文别名: 2-Hexadecyl-1,4-dimethoxy-benzol；2-Hexadecyl-1,4-dimethoxybenzene
• CAS: 105349-23-3
• 化学式: C₂₄H₄₂O₂
• 分子量: 362.596
• InChiKey: JLGHCCSOUOMBCJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.3
• 重原子数：
  26
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-十六烷基-1,4-二甲氧基苯 在 氯 、 三溴化硼 作用下， 以 二氯甲烷 、 溶剂黄146 为溶剂， 反应 9.0h， 生成 2,3,5-Trichloro-6-hexadecylcyclohexa-2,5-diene-1,4-dione
  参考文献：
  名称：

  Hydrophobic Acceleration of Electron Transfer Processes

  摘要：

  Electron transfer processes between 1-alpha-naphthyl-3-oxa-alkanes (1-n, n = 1, 8, 12, 16) and 2-alkyl-3,5,6-trichloro-1,4-benzoquinones (2-n, n = 8, 12, 16) facilitated by hydrophobic-lipophilic interactions (HLI) have been investigated by means of fluorescence spectroscopy in dioxane-H2O systems of different psi values, where psi is the volume fraction of the organic component of an aquiorgano mixture. Three lines of evidence, namely, EPR, UV-vis, and fluorescence quenching, indicate that electron transfer between 1-12 and 2-12 has occurred. Furthermore, both UV-vis evidence and the near constancy of the life time tau of 1-12* in the presence of different concentrations of the quencher 2-12 show that the electron transfer is preceded by preassociation, i.e., the quenching process is static. Therefore, the extent of HLI-driven coaggregation (preassociation) between the donors and the accepters may be assessed from the Stern-Volmer slopes (Ksv). The chain-length effect, and possibly also a chain-foldability effect, has been observed. A notable observation is the importance of solvent aggregating power (SAgP) effect, which is indicated by the surge of Ksv values at psi less than or equal to 0.40 (dioxane-H2O) for monomeric 1-12.

  DOI：

  10.1021/jo960249s
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 、 amalgamated zinc 作用下， 生成 2-十六烷基-1,4-二甲氧基苯
  参考文献：
  名称：

  136.一些烷基喹诺酚和相关化合物

  摘要：

  DOI：

  10.1039/jr9420000659

文献信息

• Novel Cytotoxic, Alkylated Hydroquinones from <i>Lannea welwitschii</i>
  作者：Amiram Groweiss、John H. Cardellina、Lewis K. Pannell、Duangchan Uyakul、Yoel Kashman、Michael R. Boyd

  DOI：10.1021/np960435t

  日期：1997.2.1

  Two novel natural products, lanneaquinol (1) and 2'(R)-hydroxylanneaquinol (2), were isolated from the organic extract of the plant Lannea welwitschii (Hiern) Engl. Their structures were solved by spectroanalytical methods and confirmed by comparison to synthetic models. The absolute configuration of 2 was determined by the modified Mosher method. Both compounds exhibited modest cytotoxicity against

  从植物Lannea welwitschii（Hiern）Engl的有机提取物中分离出了两种新颖的天然产物羊毛脂（1）和2'（R）-羟基羊毛脂（2）。通过光谱分析方法解析了它们的结构，并通过与合成模型进行比较来证实了它们的结构。2的绝对构型通过改进的Mosher方法确定。两种化合物均对60种人类肿瘤细胞系的NCI组显示出适度的细胞毒性。还阐明了两个异构的4,5-二羟基-5-烷基-2-环己烯酮（7和8）的结构，它们似乎是1和2的生物遗传前体。
• 136. Some alkyl quinols and related compounds
  作者：A. H. Cook、I. M. Heilbron、F. B. Lewis

  DOI：10.1039/jr9420000659

  日期：——
• Hydrophobic Acceleration of Electron Transfer Processes
  作者：Ji-Liang Shi、Xin Chen、Xi-Kui Jiang

  DOI：10.1021/jo960249s

  日期：1996.1.1

  Electron transfer processes between 1-alpha-naphthyl-3-oxa-alkanes (1-n, n = 1, 8, 12, 16) and 2-alkyl-3,5,6-trichloro-1,4-benzoquinones (2-n, n = 8, 12, 16) facilitated by hydrophobic-lipophilic interactions (HLI) have been investigated by means of fluorescence spectroscopy in dioxane-H2O systems of different psi values, where psi is the volume fraction of the organic component of an aquiorgano mixture. Three lines of evidence, namely, EPR, UV-vis, and fluorescence quenching, indicate that electron transfer between 1-12 and 2-12 has occurred. Furthermore, both UV-vis evidence and the near constancy of the life time tau of 1-12* in the presence of different concentrations of the quencher 2-12 show that the electron transfer is preceded by preassociation, i.e., the quenching process is static. Therefore, the extent of HLI-driven coaggregation (preassociation) between the donors and the accepters may be assessed from the Stern-Volmer slopes (Ksv). The chain-length effect, and possibly also a chain-foldability effect, has been observed. A notable observation is the importance of solvent aggregating power (SAgP) effect, which is indicated by the surge of Ksv values at psi less than or equal to 0.40 (dioxane-H2O) for monomeric 1-12.