3t-[2]furyl-acrylic acid propyl ester | 63485-68-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3t-[2]furyl-acrylic acid propyl ester
• 英文别名: 3t-[2]Furyl-acrylsaeure-propylester；propyl 3-(2-furyl)acrylate；propyl (E)-3-(furan-2-yl)prop-2-enoate
• CAS: 63485-68-7
• 化学式: C₁₀H₁₂O₃
• 分子量: 180.203
• InChiKey: RRFBKGHLBNBFGL-AATRIKPKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  39.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3t-[2]furyl-acrylic acid propyl ester 、 亚磷酸二乙酯 在 sodium ethanolate 作用下， 以 乙醇 为溶剂， 反应 6.0h， 以44%的产率得到propyl 3-diethoxyphosphoryl-3-(furan-2-yl)propanoate
  参考文献：
  名称：

  Pevzner, L.M.; Ignat'ev, V.M.; Ionin, B.I., Journal of general chemistry of the USSR, 1986, vol. 56, # 7, p. 1302 - 1304

  摘要：

  DOI：
• 作为产物：
  描述：

  丙醇 、 (E)-3-(2-呋喃)丙烯酰氯 在 吡啶 、 苯 作用下， 生成 3t-[2]furyl-acrylic acid propyl ester
  参考文献：
  名称：

  2-呋喃丙烯酸酯。

  摘要：

  DOI：

  10.1021/ja01194a501

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• Reactions de wittig-horner et de transesterification en une operation par activation anionique de liaisons C-H et O-H en milieu heterogene carbonate de potassium/alcool
  作者：Z. Mouloungui、R. Elmestour、M. Delmas、A. Gaset

  DOI：10.1016/s0040-4020(01)90785-9

  日期：1992.1

  The Wittig-Horner reaction carried out in various alcohols is accompanied by transesterification of the alkyl radical of the α, β-ethylenic ester formed. The occurrence of these two reactions in the same reaction medium is affected by the behavior of: i) the alcohol (solvent and reagent), ii) potassium carbonate (reagent and catalyst). The propensity for the two reactions to occur was found to depend

  在多种醇中进行的维蒂希-霍纳反应伴随着所形成的α，β-乙烯酯的烷基的酯交换反应。这两个反应在同一反应介质中的发生受到以下行为的影响：i）醇（溶剂和试剂），ii）碳酸钾（试剂和催化剂）。发现发生两个反应的倾向取决于醇的极性。质子醇加快了Wittig-Horner和随后的酯交换反应的速度。尽管使用了非化学计量的碳酸钾，但两个反应都是定量的。原位再生在这些反应条件下，在非质子介质中观察到的固体碱的含量显着提高。为这两个反应提出的机理包括该再生过程。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• Hair Processing Agent And Method For Permanent Waving Hair
  申请人：Shibuya Akira

  公开号：US20080085251A1

  公开（公告）日：2008-04-10

  Provided are hair processing agents capable of permanent waving hair even at a neutral to weakly acidic pH range that causes less irritation to the skin, and hair processing agents in which an unpleasant odor is masked. Hair processing agents contain at least one compound represented by the formula (2). Hair processing agents contain a compound of the formula (2) and at least one compound (ii) selected from thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine, salts thereof and ester derivatives thereof. Hair processing agents contain a compound of the formula (2), a surfactant and water, and are emulsified. Hair processing agents contain a compound of the formula (2) and a specific perfume. wherein X is a structure selected from —O—, —S—, —NH— and —NR 1 —; R 1 is an alkyl group of 1 to 6 carbon atoms; Y is an oxygen atom or a sulfur atom; in the formula (1), Z is a divalent organic residue having at least one mercapto group; in the formula (2), R is a divalent organic residue optionally having a mercapto group; and R 2 is a hydrogen atom or an alkyl group of 1 to 6 carbon atoms.

  提供了能够在中性至微酸性pH范围内进行永久性卷发的头发处理剂，其对皮肤刺激较小，并且掩盖了不愉快的气味。头发处理剂包含至少一种由公式（2）表示的化合物。头发处理剂包含公式（2）的化合物和至少一种从巯基乙酸，巯基乳酸，半胱氨酸，乙酰半胱氨酸，半胱氨醇，酰基半胱氨醇，其盐和酯衍生物中选择的化合物（ii）。头发处理剂包含公式（2）的化合物，表面活性剂和水，并且是乳化的。头发处理剂包含公式（2）的化合物和特定香水。其中X是从-O-，-S-，-NH-和-NR1-选择的结构；R1是1到6个碳原子的烷基；Y是氧原子或硫原子；在公式（1）中，Z是具有至少一个巯基的二价有机残基；在公式（2）中，R是二价的有机残基，可选地具有巯基；R2是氢原子或1到6个碳原子的烷基。
• DEODORANT COMPOSITION
  申请人：Takasago International Corporation

  公开号：EP1561476A1

  公开（公告）日：2005-08-10

  It is intended to provide a novel deodorant composition which is excellent in the deodorizing effect, is capable of affording a deodorant composition by a convenient method, and shows no decrease in the deodorizing performance even after a long period of time, once the deodorant being prepared. Specifically, there is provided a deodorant composition containing, as the active component, a colored compound obtainable by reacting a polyphenol in a solvent showing alkalinity in the coexistence of an oxygen molecule at a reaction pH value of 6.5 or more. As a substitute for a polyphenol, use can be made of a plant extract containing a polyphenol but containing substantially no amino acid. It is also possible to further employ an amino acid. Furthermore, use can be made of a plant extract and/or a plant body containing a polyphenol and an amino acid.

  本发明旨在提供一种新型除臭剂组合物，该除臭剂组合物除臭效果极佳，能够通过简便的方法获得除臭剂组合物，并且在制备除臭剂后，即使经过很长时间，除臭效果也不会降低。具体来说，本发明提供了一种除臭剂组合物，该组合物含有一种有色化合物作为活性成分，该有色化合物可通过在反应 pH 值为 6.5 或更高时，使多酚在与氧分子共存的显碱性溶剂中发生反应而获得。作为多酚的替代品，可以使用含有多酚但基本上不含氨基酸的植物提取物。也可以进一步使用氨基酸。此外，还可以使用含有多酚和氨基酸的植物提取物和/或植物体。