4,5-bis(diphenylphosphinyl)-1-pentanol | 116016-77-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,5-bis(diphenylphosphinyl)-1-pentanol
• 英文别名: 4,5-Bis(diphenylphosphinyl)pentanol；4,5-bis(diphenylphosphoryl)pentan-1-ol
• CAS: 116016-77-4
• 化学式: C₂₉H₃₀O₃P₂
• 分子量: 488.503
• InChiKey: FZOGLJWPGVWHBS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  34
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4,5-bis(diphenylphosphinyl)-1-pentanol 在 吡啶 作用下， 以 氯仿 、 N,N-二甲基甲酰胺 为溶剂， 反应 11.0h， 生成 1-Butoxy-4,5-bis(diphenylphosphinyl)pentane
  参考文献：
  名称：

  Reversible nature of the opening of the tetrahydrofuran ring of diphenyl(2-tetrahydrofurylmethyl)phosphine oxide by the diphenylphosphinite anion

  摘要：

  The reaction of diphenyl (2-tetrahydrofurylmethyl)phosphine oxide with diphenylphosphonous acid in DMSO in the presence of KOH proceeds with opening of the tetrahydrofuran ring and leads to 4,5-bis(diphenylphosphinyl) pentanol. This product is converted to the starting oxide upon the reaction with diphenylvinylphosphine oxide. 4,5-Bis(diphenylphosphinyl) pentanol is converted to the corresponding tosylate. The action of alcoholates on this tosylate gives 1-ethoxy-4,5-bis(diphenylphosphinyl)pentane and 1-butoxy-1,5-bis(diphenylphosphinyl)pentane.

  DOI：

  10.1007/bf00962400
• 作为产物：
  描述：

  2-氯甲基四氢呋喃 在 氢氧化钾 作用下， 以 二甲基亚砜 为溶剂， 反应 3.5h， 生成 4,5-bis(diphenylphosphinyl)-1-pentanol
  参考文献：
  名称：

  Reversible nature of the opening of the tetrahydrofuran ring of diphenyl(2-tetrahydrofurylmethyl)phosphine oxide by the diphenylphosphinite anion

  摘要：

  The reaction of diphenyl (2-tetrahydrofurylmethyl)phosphine oxide with diphenylphosphonous acid in DMSO in the presence of KOH proceeds with opening of the tetrahydrofuran ring and leads to 4,5-bis(diphenylphosphinyl) pentanol. This product is converted to the starting oxide upon the reaction with diphenylvinylphosphine oxide. 4,5-Bis(diphenylphosphinyl) pentanol is converted to the corresponding tosylate. The action of alcoholates on this tosylate gives 1-ethoxy-4,5-bis(diphenylphosphinyl)pentane and 1-butoxy-1,5-bis(diphenylphosphinyl)pentane.

  DOI：

  10.1007/bf00962400

文献信息

• Kharitonov, A. V.; Antoshin, A. E.; Tsvetkov, E. N., Journal of general chemistry of the USSR, 1987, vol. 57, # 10, p. 2142 - 2143
  作者：Kharitonov, A. V.、Antoshin, A. E.、Tsvetkov, E. N.

  DOI：——

  日期：——
• ANTOSHIN, A. EH.;XARITONOV, A. V.;TSVETKOV, E. N., IZV. AN CCCP. CEP. XIM.,(1990) N, S. 1421-1424
  作者：ANTOSHIN, A. EH.、XARITONOV, A. V.、TSVETKOV, E. N.

  DOI：——

  日期：——
• XARITONOV, A. V.;ANTOSHIN, A. EH.;TSVETKOV, E. N., ZH. OBSHCH. XIMII, 57,(1987) N 10, 2395-2396
  作者：XARITONOV, A. V.、ANTOSHIN, A. EH.、TSVETKOV, E. N.

  DOI：——

  日期：——
• Reversible nature of the opening of the tetrahydrofuran ring of diphenyl(2-tetrahydrofurylmethyl)phosphine oxide by the diphenylphosphinite anion
  作者：A. �. Antoshin、A. V. Kharitonov、E. N. Tsvetkov

  DOI：10.1007/bf00962400

  日期：1990.6

  The reaction of diphenyl (2-tetrahydrofurylmethyl)phosphine oxide with diphenylphosphonous acid in DMSO in the presence of KOH proceeds with opening of the tetrahydrofuran ring and leads to 4,5-bis(diphenylphosphinyl) pentanol. This product is converted to the starting oxide upon the reaction with diphenylvinylphosphine oxide. 4,5-Bis(diphenylphosphinyl) pentanol is converted to the corresponding tosylate. The action of alcoholates on this tosylate gives 1-ethoxy-4,5-bis(diphenylphosphinyl)pentane and 1-butoxy-1,5-bis(diphenylphosphinyl)pentane.