1-Propoxy-4-prop-2-ynylsulfanylbenzene | 146859-87-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-Propoxy-4-prop-2-ynylsulfanylbenzene
• CAS: 146859-87-2
• 化学式: C₁₂H₁₄OS
• 分子量: 206.309
• InChiKey: XNOQANWWJMXFMO-UHFFFAOYSA-N

物化性质

• 沸点：
  297.7±25.0 °C(Predicted)
• 密度：
  1.06±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  34.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-Propoxy-4-prop-2-ynylsulfanylbenzene 在 morpholine-iodine complex 作用下， 以 苯 为溶剂， 反应 16.0h， 以40%的产率得到1-(3-Iodoprop-2-ynylsulfanyl)-4-propoxy-benzene
  参考文献：
  名称：

  Synthesis and antifungal activity of some alkynylthio compounds

  摘要：

  Some 4-(p-alkoxyphenylthio)but-2-yn-yl-amine hydrochlorides and 4-(p-alkoxyphenylthio)prop-1-yn-yl-iodides were prepared and tested for their antifungal activity. All the tested compounds were active in inhibiting the growth of 4 fungal types. The iodine compounds were the more effective.

  DOI：

  10.1016/0223-5234(92)90118-k
• 作为产物：
  描述：

  p-Propoxythiophenol 、 3-溴丙炔 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 反应 1.0h， 以88%的产率得到1-Propoxy-4-prop-2-ynylsulfanylbenzene
  参考文献：
  名称：

  Synthesis and antifungal activity of some alkynylthio compounds

  摘要：

  Some 4-(p-alkoxyphenylthio)but-2-yn-yl-amine hydrochlorides and 4-(p-alkoxyphenylthio)prop-1-yn-yl-iodides were prepared and tested for their antifungal activity. All the tested compounds were active in inhibiting the growth of 4 fungal types. The iodine compounds were the more effective.

  DOI：

  10.1016/0223-5234(92)90118-k

文献信息

• Synthesis and antifungal activity of some alkynylthio compounds
  作者：SS Papakonstantinou-Garoufalia、AE Papadaki-Valiraki、A Chytiroglou-Lada

  DOI：10.1016/0223-5234(92)90118-k

  日期：1992.11

  Some 4-(p-alkoxyphenylthio)but-2-yn-yl-amine hydrochlorides and 4-(p-alkoxyphenylthio)prop-1-yn-yl-iodides were prepared and tested for their antifungal activity. All the tested compounds were active in inhibiting the growth of 4 fungal types. The iodine compounds were the more effective.