N-Benzyl-thioformimidomethylester | 126789-61-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-Benzyl-thioformimidomethylester
• 英文别名: Methyl benzylmethanimidothioate；methyl N-benzylmethanimidothioate
• CAS: 126789-61-5
• 化学式: C₉H₁₁NS
• 分子量: 165.259
• InChiKey: KTBMSJAVWFLCCX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  37.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-Benzyl-thioformimidomethylester 在 氯 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 trans-1-Benzyl-3-(tosyloxy)-4-chloro-2-azetidinone
  参考文献：
  名称：

  Base-promoted ring-opening and elimination of 4-chloro- and 4-(methylthio)azetidinones

  摘要：

  DOI：

  10.1021/jo00297a048
• 作为产物：
  描述：

  N-benzylthioformamide 、 碘甲烷 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 以63%的产率得到N-Benzyl-thioformimidomethylester
  参考文献：
  名称：

  Synthesis of optically active .beta.-lactams by the photolytic reaction of imines with optically active chromium carbene complexes. 2. Synthesis of 1-carbacephalothin and 3-ANA relays

  摘要：

  A relay (3) to optically active 1-carbacephalothin (4) was prepared in modest yield with high stereoselectivity by the photochemical reaction of optically active chromium carbene complex 1 with functionalized imine 2. In contrast, the photochemical reaction of carbene complex 1 with imine precursors 15a,b to the nocardicins was much less stereoselective.

  DOI：

  10.1021/jo00046a030

文献信息

• Synthesis of optically active .beta.-lactams by the photolytic reaction of imines with optically active chromium carbene complexes. 2. Synthesis of 1-carbacephalothin and 3-ANA relays
  作者：Y. Narukawa、K. N. Juneau、D. Snustad、D. B. Miller、L. S. Hegedus

  DOI：10.1021/jo00046a030

  日期：1992.9

  A relay (3) to optically active 1-carbacephalothin (4) was prepared in modest yield with high stereoselectivity by the photochemical reaction of optically active chromium carbene complex 1 with functionalized imine 2. In contrast, the photochemical reaction of carbene complex 1 with imine precursors 15a,b to the nocardicins was much less stereoselective.
• Base-promoted ring-opening and elimination of 4-chloro- and 4-(methylthio)azetidinones
  作者：S. Nagaraja Rao、Rory A. More O'Ferrall

  DOI：10.1021/jo00297a048

  日期：1990.5