3-tert-Butoxy-2,2-dimethylpropionsaeure | 35889-98-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-tert-Butoxy-2,2-dimethylpropionsaeure
• 英文别名: 3-(Tert-butoxy)-2,2-dimethylpropanoic acid；2,2-dimethyl-3-[(2-methylpropan-2-yl)oxy]propanoic acid
• CAS: 35889-98-6
• 化学式: C₉H₁₈O₃
• 分子量: 174.24
• InChiKey: UXJMDFRNKLZRPZ-UHFFFAOYSA-N

物化性质

• 沸点：
  243.7±23.0 °C(Predicted)
• 密度：
  0.977±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-tert-Butoxy-2,2-dimethylpropionsaeure 在 盐酸 、 甲醇 作用下， 生成 3-(tert-butoxy)-2,2-dimethylpropanoic acid
  参考文献：
  名称：

  Polar and steric substituent constants for an alkylperoxy group and related ether groups

  摘要：

  DOI：

  10.1021/jo00797a032
• 作为产物：
  描述：

  羟基三甲基乙酸甲酯 在 硫酸 、 potassium hydroxide 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 、 水 为溶剂， 反应 2.0h， 生成 3-tert-Butoxy-2,2-dimethylpropionsaeure
  参考文献：
  名称：

  IMIDAZO(4,5-B) PYRIDIN-2-YL AMIDES AS KV7 CHANNEL ACTIVATORS

  摘要：

  由公式1表示的化合物可能对Kv7.2/7.3异源多聚体具有强效和/或部分选择性。它们可能在治疗与癫痫、疼痛、神经递质释放等相关的疾病方面有用。

  公开号：

  US20160031875A1

文献信息

• Nitrile acrylate radiation curable coating compositions and the process of making the same
  申请人：THE STANDARD OIL COMPANY

  公开号：EP0245561A2

  公开（公告）日：1987-11-19

  Photocurable coating compositions comprising a polymer comprising a nitrile monomer and an acrylate monomer; a reactive diluent and a photoinitiator are useful as protective coatings. They may be applied to a substrate and cured. The coating compositions can be 100% solids nitrile acrylate coatings composition.

  光固化涂层组合物可用作保护涂层，该组合物包含由腈单体和丙烯酸酯单体组成的聚合物、活性稀释剂和光引发剂。 它们可涂在基材上并固化。 涂料组合物可以是 100% 固含量的丙烯酸腈涂料组合物。
• Nitrile acrylate coating composition containing pendant functionality and a radiation curable process
  申请人：THE STANDARD OIL COMPANY

  公开号：EP0257812A2

  公开（公告）日：1988-03-02

  A coating composition comprising a nitrile acrylate polymer with pendant functionality useful as protective coatings. The composition comprises a nitrile monomer, acrylate monomer and multifunctional monomer; a reactive diluent; and a photoinitiator. The composition is 100% solvent free. This invention further includes a process for producing 100 percent solids coatings that are corrosion resistant, adhesion cohesive and hard.

  一种涂料组合物，包含一种具有悬垂官能度的腈丙烯酸酯聚合物，可用作保护涂料。该组合物由腈单体、丙烯酸酯单体和多功能单体、活性稀释剂和光引发剂组成。该组合物 100% 不含溶剂。 本发明还包括一种生产耐腐蚀、附着力强且坚硬的 100%固体涂料的工艺。
• Thermoplastic resin composition and article comprising the same
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0456259A1

  公开（公告）日：1991-11-13

  A thermoplastic resin composition containing a polyamide resin composition (C) consisting of a polyamide resin (A) and another thermoplastic resin (B) and at least one modifier (D) is excellent in coatability, mechanical properties, linear expansion coefficient and appearance, can be molded into an article which comprises the polyamide resin (C), wherein the ratio of the percent occupied area of the polyamide resin on the surface of the article to the weight percentage of the polyamide in the polyamide resin composition (C) is not less than l.2, and/or the ratio of the percent concentration of the polyamide resin on the surface of the article determined on the basis of the nitrogen concentration on the surface of the article to the weight percentage of the polyamide in the polyamide resin composition (C) is not less than l,2, which article is suited for electric and electronic parts and automobile parts such as a bumper, fender and wheel cover.

  一种含有聚酰胺树脂组合物(C)的热塑性树脂组合物，该组合物由聚酰胺树脂(A)和另一种热塑性树脂(B)以及至少一种改性剂(D)组成，具有优异的涂覆性、机械性能、线膨胀系数和外观，可以模塑成包含聚酰胺树脂(C)的制品，其中制品表面聚酰胺树脂所占面积百分比与聚酰胺树脂组合物(C)中聚酰胺的重量百分比之比不小于 l.2、和/或根据物品表面氮浓度确定的物品表面聚酰胺树脂浓度百分比与聚酰胺树脂组合物(C)中聚酰胺重量百分比之比不小于l,2，该物品适用于电气和电子零件以及汽车零件，如保险杠、挡泥板和车轮罩。
• METHOD FOR PRODUCING FLUORINE-CONTAINING POLYMER
  申请人：Asahi Glass Company, Limited

  公开号：EP3150645A1

  公开（公告）日：2017-04-05

  To provide an effective process for producing a fluorinated polymer excellent in adhesion, by using a polymerization medium having a low ozone layer destruction potential. A process for producing a fluorinated polymer, which comprises polymerizing a monomer mixture comprising a fluorinated monomer and a polar functional group-containing monomer (excluding one having a fluorine atom) in a polymerization medium, wherein the polymerization medium contains a medium compound represented by CmH2m+1-xFx-O-CnH2n+1-yFy (wherein m is an integer of from 1 to 6, n is an integer of from 1 to 6, x is from 0 to (2m+1), y is from 0 to 2n, and (x+y) is at least 1), and wherein a solution obtained by dissolving the polar functional group-containing monomer in the polymerization medium is continuously or intermittently added to a polymerization reaction system.

  通过使用一种臭氧层破坏潜能值较低的聚合介质，提供一种生产粘附性优异的含氟聚合物的有效工艺。 一种生产含氟聚合物的工艺，它包括在聚合介质中聚合由含氟单体和含极性官能团单体（不包括具有氟原子的单体）组成的单体混合物，其中聚合介质含有由 CmH2m+1-xFx-O-CnH2n+1-yFy 表示的介质化合物（其中 m 为 1 至 6 的整数，n 为 1 至 6 的整数，x 为 0 至 (0) 的整数）、n为 1 至 6 的整数，x 为 0 至 (2m+1)，y 为 0 至 2n，(x+y)至少为 1），通过将含极性官能团的单体溶解在聚合介质中得到的溶液连续或间歇地加入到聚合反应体系中。
• Imidazo(4,5-B) pyridin-2-yl amides as KV7 channel activators
  申请人：Knopp Biosciences LLC

  公开号：US10106536B2

  公开（公告）日：2018-10-23

  Compounds represented by formula 1 can be potent and/or partially selective for the Kv7.2/7.3 heteromultimer. They may be useful in treating disorders related to seizures, pain, neurotransmitter release, etc.

  式 1 所代表的化合物对 Kv7.2/7.3 异源二聚体具有强效和/或部分选择性。它们可用于治疗与癫痫发作、疼痛、神经递质释放等有关的疾病。