2,5-dimethylmuconic acid | 20514-40-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,5-dimethylmuconic acid
• 英文别名: dimethylmuconic acid；buta-1,3-diene-1,4-dimethyl-1,4-dioic acid；2,5-dimethyl-hexa-2c,4c-dienedioic acid；2,5-Dimethyl-hexa-2c,4c-diendisaeure；cis-cis-2,5-Dimethyl-muconsaeure；(2Z,4Z)-2,5-dimethylhexa-2,4-dienedioic acid
• CAS: 20514-40-3
• 化学式: C₈H₁₀O₄
• 分子量: 170.165
• InChiKey: HVMNFKUBOVSQCO-GLIMQPGKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2917190090

反应信息

• 作为反应物：
  描述：

  2,5-dimethylmuconic acid 在 硫酸 作用下， 生成 2,5-Dimethyl-2-hexendisaeure-1,4-lacton
  参考文献：
  名称：

  Elvidge et al., Journal of the Chemical Society, 1952, p. 1026,1031

  摘要：

  DOI：
• 作为产物：
  描述：

  2,5-二甲基苯酚 在 过氧乙酸 、 溶剂黄146 作用下， 生成 2,5-dimethylmuconic acid
  参考文献：
  名称：

  Elvidge et al., Journal of the Chemical Society, 1952, p. 1026,1031

  摘要：

  DOI：

文献信息

• Andrographolide derivatives to treat viral infections
  申请人：Liu Hai Rui

  公开号：US20060223785A1

  公开（公告）日：2006-10-05

  The present invention provides a methods and compositions for treating a host afflicted with a viral infection, particularly a Flaviviridae infection, including hepatitis C infection, comprising administering an effective antiviral amount of a derivative of andrographolide alone or in combination or alternation with another antiviral compound.

  本发明提供了一种治疗病毒感染宿主的方法和组合物，特别是病毒科感染，包括丙型肝炎感染，包括单独或与另一种抗病毒化合物联合或交替使用有效抗病毒量的穿心莲内酯衍生物。
• Diene conformation in the naturally occurring tricarboxylic acid, telfairic acid, by Raman spectroscopy
  作者：Howell G.M. Edwards、Raymond L. Edwards、Melanie J. Hartley、Michael Quinn

  DOI：10.1016/j.molstruc.2005.12.012

  日期：2006.5

  The conformational geometry of the two C=C bonds in a naturally occurring dienetricarboxylic acid, telfairic acid, isolated from Xylaria telfairii, has been determined by Raman spectroscopy. This application of analytical Raman spectroscopy is important because infrared, UV and NMR spectroscopic techniques have failed to provide sufficient information for the determination of the diene geometry. Several specially synthesised model dienecarboxylic acids with known diene conformations were used to calibrate the Raman data. The natural extract from X. telfairii was shown to be a mixture of both cis (Z) and trans (E) forms whereas the purified extract was predominantly the trans isomer. Raman data also suggest that the established method for the preparation of a trans-trans sorbic acid is open to debate. Further applications of the Raman technique for the determination of diene conformation of fungal metabolite extracts are proposed. (c) 2006 Elsevier B.V. All rights reserved.
• ANDROGRAPHOLIDE DERIVATIVES TO TREAT VIRAL INFECTIONS
  申请人：CORNELL RESEARCH FOUNDATION, INC.

  公开号：EP1817024A2

  公开（公告）日：2007-08-15
• SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM
  申请人：Trimpin Sarah

  公开号：US20150053854A1

  公开（公告）日：2015-02-26

  Disclosed herein are systems and methods that allow analysis of macromolecular structures using laserspray ionization at intermediate pressure or high vacuum using commercially available mass spectrometers with or without modification and with the application of heat. The systems and methods produce multiply-charged ions for improved analysis in mass spectrometry.
• US5476933A
  申请人：——

  公开号：US5476933A

  公开（公告）日：1995-12-19