dodeca-2t,4t,8c-trienoic acid | 882027-09-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: dodeca-2t,4t,8c-trienoic acid
• 英文别名: Dodeca-2t,4t,8c-triensaeure；(2E,4E,8Z)-dodeca-2,4,8-trienoic acid
• CAS: 882027-09-0
• 化学式: C₁₂H₁₈O₂
• 分子量: 194.274
• InChiKey: SUAIANONRYUFAT-QYHQRLDKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  dodeca-2t,4t,8c-trienoic acid 、 异丁胺 生成 (2E,4E,8Z)-N-isobutyldodeca-2,4,8-trienamide
  参考文献：
  名称：

  蔬菜来源的酰胺。第七部分 合成ñ -异butyldodeca-反式-2：反式-4：反式-8-和反式-2：反式-4：顺-8- trienamide及其与山椒我关系

  摘要：

  DOI：

  10.1039/jr9550004244
• 作为产物：
  描述：

  dec-6c-en-2-ynal-diethylacetal 在 吡啶 、 Lindlar's catalyst 、 硫酸 、 乙酸乙酯 作用下， 生成 dodeca-2t,4t,8c-trienoic acid
  参考文献：
  名称：

  蔬菜来源的酰胺。第七部分 合成ñ -异butyldodeca-反式-2：反式-4：反式-8-和反式-2：反式-4：顺-8- trienamide及其与山椒我关系

  摘要：

  DOI：

  10.1039/jr9550004244

文献信息

• E2, E4,Z8-undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same
  申请人：INTERNATIONAL FLAVORS & FRAGRANCES INC.

  公开号：EP2112135A2

  公开（公告）日：2009-10-28

  Described is a genus of undecatrienoic acid derivatives useful in imparting, augmenting and/or enhancing flavors, aromas and somatosensory effects in or to consumable materials such as foods, beverages, skin care products, oral care products, medicinal products and the like. Also described is a synthesis process for producing such derivatives.

  描述的是一种十一碳三烯酸衍生物，可用于赋予、增强和/或提高食品、饮料、护肤品、口腔护理产品、医药产品等消费品的风味、香气和体感效果。此外，还描述了生产此类衍生物的合成工艺。
• E2, E4,Z8-Undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same
  申请人：INTERNATIONAL FLAVORS & FRAGRANCES INC.

  公开号：EP1496042B1

  公开（公告）日：2009-11-11
• INHIBITORS OF ANOREXIC LIPID HYDROLYSIS FOR THE TREATMENT OF EATING DISORDERS
  申请人：Hansen Harald S.

  公开号：US20090054526A1

  公开（公告）日：2009-02-26

  Compounds, pharmaceuticals, cosmetic or dietary supplements for the treatment of overweight, obesity and/or type II diabetes in a mammal (e.g. human) comprising a compound with formula I or formula II for example ceramidase-inhibitor, such as (1S,2R)-D-ery-thro-2-(N-myristoylamino)-1-phenyl-1-propanol, alone or in combination with an anorexic lipid (or other appetite-inhibiting acylamides or oleoyl-estrone), and methods of treatment comprising administration of said compounds, pharmaceuticals, cosmetic or a dietary supplements. The compounds, pharmaceuticals, cosmetic or dietary supplements and methods of the invention may further be used in modifying the feeding behaviour, suppression of hunger, enhancement of satiety, reduction of energy intake, reduction of fat tissue mass/lean mass ratio in a mammal (e.g. human).
• Amides of vegetable origin. Part VII. Synthesis of N-isobutyldodeca-trans-2 : trans-4 : trans-8- and trans-2 : trans-4: cis-8-trienamide and their relation to sanshoöl I
  作者：L. Crombie、J. D. Shah

  DOI：10.1039/jr9550004244

  日期：——