1-isopentyl-2-nitro-benzene | 3443-71-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-isopentyl-2-nitro-benzene
• 英文别名: 1-Isopentyl-2-nitro-benzol；2-(3-methylbutyl)nitrobenzene；1-(3-methylbutyl)-2-nitrobenzene
• CAS: 3443-71-8
• 化学式: C₁₁H₁₅NO₂
• 分子量: 193.246
• InChiKey: OHQRLPNHIRFOEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-isopentyl-2-nitro-benzene 在 盐酸 、 tin 、 硫酸 、 硝酸 、 铁粉 作用下， 生成 N,N'-(4-isopentyl-m-phenylene)-bis-acetamide
  参考文献：
  名称：

  Harvey, Journal of the Chemical Society, 1958, p. 2060

  摘要：

  DOI：
• 作为产物：
  描述：

  3-methyl-1-phenyl-1-butene 在 乙醇 、 硫酸 、 硝酸 、 镍 作用下， 60.0 ℃ 、4.9 MPa 条件下， 生成 1-isopentyl-2-nitro-benzene
  参考文献：
  名称：

  Harvey, Journal of the Chemical Society, 1958, p. 2060

  摘要：

  DOI：

文献信息

• Inhibitors of the Human Aldosterone Sythase CYP11B2
  申请人：Hartmann Rolf W.

  公开号：US20110112067A1

  公开（公告）日：2011-05-12

  The invention provides compounds of the general formula (I) which are inhibitors of the human aldosterone synthase, and also pharmaceutical compositions containing these compounds, and a method of treating of hyperaldosteronism and/or disorders or diseases that are mediated by 11β-hydroxylase (CYP11B1) with these compounds.

  该发明提供了一般式(I)的化合物，这些化合物是人类醛固酮合成酶的抑制剂，还包括含有这些化合物的药物组合物，以及使用这些化合物治疗高醛固酮症和/或由11β-羟化酶（CYP11B1）介导的疾病或疾病的方法。
• Substituted carboxanilide derivative and plant disease control agent
  申请人：Mitsui Chemicals, Inc.

  公开号：US05914344A1

  公开（公告）日：1999-06-22

  A substituted carboxanilide derivative represented by the formula (1): ##STR1## wherein A is a hydrogen atom or methyl, B is a methyl or ethyl, and Het is 1-methyl-3-substituted-4-pyrazolyl or 2-methyl-4-substituted-5-triazoyl group, exhibits a disease control effect against Botrytis cinerea, Powdery mildew, Pyricularia oryzae of rice plant and other various plant diseases, is excellent in residual effect, has also activity against resistant strain for conventional chemicals, particularly exerts control effects against Botrytis cinerea at a lower dosage as compared with a prior art, is also safe for crops, and thus is useful as a plant control agent.

  一种代表为以下式（1）的取代羧酰苯胺衍生物：其中A是氢原子或甲基，B是甲基或乙基，Het是1-甲基-3-取代-4-吡唑基或2-甲基-4-取代-5-三唑基团，对灰霉病菌、白粉病菌、水稻稻瘟病菌和其他各种植物病害具有良好的病害控制效果，残效性优良，对传统化学药剂的耐药菌株也具有活性，尤其在比较之下，对灰霉病菌的控制效果在较低剂量下表现出色，同时对作物安全，因此可作为植物防治剂使用。
• Substituted anilide derivative
  申请人：Mitsui Chemicals, Inc.

  公开号：US05965774A1

  公开（公告）日：1999-10-12

  A substituted anilide derivative represented by the formula (2): ##STR1## wherein A and B are methyl, and X is a hydrogen atom. The substituted anilide can be used to prepare a substituted carboxanilide derivative that exhibits a disease control effect against Botrytis cinerea, Powdery mildew, Pyricularia oryzae of rice plant and other various plant diseases, is excellent in residual effect, has activity against strains that are resistant to conventional chemicals, is safe for crops, and thus is useful as a plant disease control agent.

  一个由公式（2）表示的取代苯胺衍生物：##STR1## 其中A和B为甲基，X为氢原子。该取代苯胺可以用于制备取代羧基苯胺衍生物，对灰霉病、白粉病、水稻稻瘟病原菌等各种植物病害具有控制效果，具有优异的残留效果，对传统化学品抗性菌株具有活性，对作物安全，因此是一种有用的植物病害防治剂。
• 6-Pyridin-3-YL-3,4-Dihydro-1H-Quinolin-2-One Derivatives and Related Compounds as Inhibitors of the Human Aldosterone Synthase CYP11B2
  申请人：Hartmann Rolf W.

  公开号：US20110118241A1

  公开（公告）日：2011-05-19

  The invention provides compounds of the general formula (I) which are inhibitors of the human aldosterone synthase, and also pharmaceutical compositions containing these compounds, and the use of these compounds and other heteroaryl substituted quinolinone derivatives for the treatment of hyperaldosteronism and/or disorders or diseases that are mediated by 11 β-hydroxylase (CYP11 B1).

  本发明提供了一般式(I)的化合物，它们是人类醛固酮合成酶的抑制剂，还提供了含有这些化合物的制药组合物以及使用这些化合物和其他杂环取代喹啉酮衍生物治疗高醛固酮症和/或11β-羟化酶(CYP11B1)介导的疾病或疾病的方法。
• Method for producing an aromatic compound having an alkyl group with at least three carbon atoms
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP0985649A2

  公开（公告）日：2000-03-15

  Aromatic compounds having an alkyl group with at least 3 carbon atoms are produced in a process comprising at least one of the following steps: (1) a step of contacting a starting material that contains an aromatic compound having a branched alkyl group with at least 3 carbon atoms, with a zeolite-containing catalyst in a liquid phase in the presence of hydrogen therein, thereby changing the position of the carbon atoms of the alkyl group bonding to the aromatic ring of the compound; (2) a step of contacting a starting material that contains an aromatic compound having a branched alkyl group with at least 3 carbon atoms, with a catalyst containing zeolite and containing rhenium and/or silver, in a liquid phase, thereby changing the position of the carbon atoms of the alkyl group bonding to the aromatic ring of the compound; (3) a step of contacting a halogenated aromatic compound having an alkyl group with at least 3 carbon atoms, with an acid-type catalyst, thereby isomerizing the compound; and (4) a step of treating a mixture of isomers of an aromatic compound having an alkyl group with at least 3 carbon atoms, with a zeolite adsorbent that contains at least one exchangable cation selected from alkali metals, alkaline earth metals, lead, thallium and silver, thereby separating a specific isomer from the isomer mixture through adsorption.

  具有至少 3 个碳原子烷基的芳香族化合物的生产工艺至少包括以下一个步骤： (1) 将含有至少 3 个碳原子的支链烷基的芳香族化合物的起始原料在液相中与含沸石的催化剂在氢存在的情况下接触，从而改变烷基的碳原子与化合物的芳香环键合的位置； (2) 将含有芳香族化合物的起始原料与含沸石和含铼和/或银的催化剂在液相中接触，该芳香族化合物具有至少 3 个碳原子的支链烷基，从而改变烷基碳原子与化合物芳香环键合的位置； (3) 将具有至少 3 个碳原子的烷基的卤代芳香族化合物与酸型催化剂接触，从而使该化合物异构化；以及 (4) 用沸石吸附剂处理具有至少 3 个碳原子的烷基的芳香族化合物的异构体混合物，该沸石吸附剂含有至少一种选自碱金属、碱土金属、铅、铊和银的可交换阳离子，从而通过吸附从异构体混合物中分离出特定的异构体。