N,N-dibutyl-nonanamide | 57303-24-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N,N-dibutyl-nonanamide
• 英文别名: N,N-Dibutyl-nonanamid；Nonansaeure-dibutylamid；N,N-dibutylnonanamide；Nonanoic acid dibutylamide
• CAS: 57303-24-9
• 化学式: C₁₇H₃₅NO
• 分子量: 269.471
• InChiKey: OLWWMZKVJBISLO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  19
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N-dibutyl-nonanamide 在 lithium aluminium tetrahydride 作用下， 生成 1-Dibutylamino-nonan
  参考文献：
  名称：

  Über hochverzweigte aliphatische Verbindungen

  摘要：

  DOI：

  10.1007/bf00903144
• 作为产物：
  描述：

  1-庚烯 、 2-溴-N,N-二丁基乙酰胺 在 diborane(6) 、 lithium diisopropyl amide 作用下， 生成 N,N-dibutyl-nonanamide
  参考文献：
  名称：

  Facile homologation of N,N-dialkyl-.alpha.-bromoacetamide by trialkylboranes in the presence of lithium diisopropylamide

  摘要：

  DOI：

  10.1021/jo00074a046

文献信息

• Penetration enhancers for transdermal delivery of systemic agents
  申请人：WHITBY RESEARCH, Inc.

  公开号：EP0268220A2

  公开（公告）日：1988-05-25

  This invention relates to a method for administering systemically active agents including therapeutic agents through the skin or mucosal membranes of humans and animals in a transdermal device or formulation comprising topically administering with said systemic agent an effective amount of a membrane penetration enhancer having the structural formula wherein R¹ and R² are independently selected from the group consisting of alkyl radicals and cycloalkyl radicals comprising from 1 to 20 carbon atoms and R is selected from the group consisting of alkyl radicals and cycloalkyl radicals comprising from 1 to 30 carbon atoms; provided, however, that the total number of carbon atoms in said compound is 15 or more and the total number of carbon atoms in R¹ and R² is 5 or more.

  本发明涉及一种在透皮装置或制剂中通过人和动物的皮肤或粘膜施用包括治疗剂在内的全身活性制剂的方法，该方法包括与所述全身制剂一起局部施用有效量的具有结构式的膜渗透促进剂 其中 R¹ 和 R² 独立地选自由 1 至 20 个碳原子的烷基和环烷基组成的组，R 选自由 1 至 30 个碳原子的烷基和环烷基组成的组；但前提是所述化合物中的碳原子总数为 15 个或更多，且 R¹ 和 R² 中的碳原子总数为 5 个或更多。
• EP0329669A4
  申请人：——

  公开号：EP0329669A4

  公开（公告）日：1989-12-12
• COMPOSITIONS COMPRISING N,N-DIALKYLALKANAMIDES AND THEIR USES
  申请人：Whitby Research Incorporated

  公开号：EP0329669A1

  公开（公告）日：1989-08-30
• AGROCHEMICAL COMPOSITION AND METHOD FOR PREPARING AND USING THE SAME
  申请人：Yin Amanda

  公开号：US20120071530A1

  公开（公告）日：2012-03-22

  An agrochemical composition comprises an azole active ingredient and an N,N-dialkyl long chain alkylamide. The N,N-dialkyl long chain alkylamide is present in sufficient amount to prevent or inhibit the crystallization of the azole derivative during the application of the composition to a locus. Preferred N,N-Dialkyl long chain alkylamide(s) comprised in the composition is/are selected from the group consisting of compounds of the formula (I): in which (a) R 1 and R 2 are independently normal alkyl radicals having 2 carbon atoms, and R represents an alkyl group having from 10 to 30 carbon atoms; or (b) R 1 and R 2 are independently normal alkyl radicals having 3 carbon atoms, and R represents an alkyl group having from 9 to 30 carbon atoms; or 20 (c) R 1 and R 2 are independently normal alkyl radicals having from 4 to 20 carbon atoms and R represents an alkyl group having from 6 to 30 carbon atoms. The composition is particularly advantageous when formulated with a fungicide, in particular one or more of tebuconazole, cyproconazole, difenoconazole, diniconazole, triticonazole, hexaconazole, triflumiazole, metconazole, tricylazole, flusilazole, flutriafol, and myclobutanil.
• US4808414A
  申请人：——

  公开号：US4808414A

  公开（公告）日：1989-02-28