2,3-O-diacetyl-L-tartaric acid dichloride | 125367-16-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,3-O-diacetyl-L-tartaric acid dichloride
• 英文别名: O,O-diacetyltartaric dichloride；[(2R,3R)-3-acetyloxy-1,4-dichloro-1,4-dioxobutan-2-yl] acetate
• CAS: 125367-16-0
• 化学式: C₈H₈Cl₂O₆
• 分子量: 271.054
• InChiKey: HIFJACZLIZHJFC-PHDIDXHHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.38
• 重原子数：
  16.0
• 可旋转键数：
  5.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  86.74
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  4-氨基-TEMPO 、 2,3-O-diacetyl-L-tartaric acid dichloride 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以85%的产率得到(R,R)-(+)-2,3-diacetoxy-N,N'-bis(2,2,6,6-tetramethylpiperidin-1-oxyl-4-yl)succinyl diamide
  参考文献：
  名称：

  Evaluation of spin labeled tartaric and galactaric diamides as potential MRI contrast enhancing agents

  摘要：

  DOI：

  10.1016/0223-5234(89)90005-6

文献信息

• Synthesis of Heterofunctionalized Multidentate Diphosphines
  作者：Michael Quirmbach、Jens Holz、Vitali I Tararov、Armin Börner

  DOI：10.1016/s0040-4020(99)01075-3

  日期：2000.1

  The synthesis of new chiral multidentate amino- and amidophosphine ligands bearing up to six potential coordination sites were synthesized starting from L-valine. Based on these compounds chiral Ru(II) complexes were prepared, characterized and tested in the asymmetric transfer hydrogenation of aryl-alkyl ketones. In all cases investigated the catalyst bearing additional hydroxy groups gave lower conversions than the complex without hydroxy groups. Highest enantioselectivity was achieved with isobutyrophenone as substrate (69%ee). (C) 2000 Elsevier Science Ltd. All rights reserved.