4-氯-2,3-二氢-1H-茚 | 15115-61-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 中文名称: 4-氯-2,3-二氢-1H-茚
• 英文名称: 4-chloro-indan
• 英文别名: 4-Chlor-indan；4-Chlorindan；4-Chloro-2,3-dihydro-1H-indene
• CAS: 15115-61-4
• 化学式: C₉H₉Cl
• mdl: MFCD15146828
• 分子量: 152.623
• InChiKey: HHMPPXIOARAANX-UHFFFAOYSA-N

物化性质

• 沸点：
  229.3±29.0 °C(Predicted)
• 密度：
  1.169±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  4-氯-2,3-二氢-1H-茚 在 乙醚 、 lithium 作用下， 生成 4-(2-羟乙基)-茚满
  参考文献：
  名称：

  The Use of 4-Substituted Hydrindenes in the Preparation of Cyclopentanophenanthrene Derivatives

  摘要：

  DOI：

  10.1021/ja01176a011
• 作为产物：
  描述：

  3-(2-氯苯基)丙酸 在 盐酸 、 汞 、 锌 作用下， 生成 4-氯-2,3-二氢-1H-茚
  参考文献：
  名称：

  Faller,P., Bulletin de la Societe Chimique de France, 1966, p. 3618 - 3625

  摘要：

  DOI：

文献信息

• NOVEL METHINE DYES
  申请人：LANXESS Deutschland GmbH

  公开号：US20190112485A1

  公开（公告）日：2019-04-18

  The present invention relates to novel methine dyes, methods for the preparation thereof and use thereof for dyeing plastics, especially polyamides, so as to obtain yellow to orange colourings with improved light fastness and improved thermal stability.

  本发明涉及新型甲纶染料，其制备方法和用于染色塑料，特别是聚酰胺，以获得改善光牢度和热稳定性的黄色至橙色着色剂。
• THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
  申请人：Suzuki Masaki

  公开号：US20150307477A1

  公开（公告）日：2015-10-29

  Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit.

  本文描述了利用调节纹状体富集的酪氨酸磷酸酶（STEP）的化合物来治疗疾病的方法。示例疾病包括精神分裂症和认知缺陷。
• [EN] SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF<br/>[FR] DERIVE D'ACIDE ARYLALCANOIQUE SUBSTITUE ET SON UTILISATION
  申请人：ASAHI KASEI PHARMA CORP

  公开号：WO2005016862A1

  公开（公告）日：2005-02-24

  A compound represented by the formula (I)[In the formula, Link represents a saturated or unsaturated straight hydrocarbon chain having 1 to 3 carbon atoms, C2 to C6 in the aromatic ring (E) independently represent a ring-constituting carbon atom, one of the ring-constituting carbon atoms may be replaced with V, V represents nitrogen atom, or carbon atom substituted with Zx, Zx represents a saturated alkyl group having 1 to 4 carbon atoms and the like, Rs represents -D-Rx etc., D represents a single bond, oxygen atom and the like, Rx represents a saturated alkyl group having 3 to 8 carbon atoms and the like, AR represents a partially unsaturated or completely unsaturated condensed bicyclic carbon ring or a heterocyclic ring, and Y represents hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms and the like] or a salt thereof. A compound having prostaglandin production-suppressing action and leukotriene production-suppressing action is provided.

  化合物的化学式为（I）。在该式中，Link代表一个由1至3个碳原子组成的饱和或不饱和直链烃链，芳环（E）中的C2至C6独立代表构成环的碳原子，构成环的碳原子中的一个可以被V取代，V代表氮原子，或者被Zx取代的碳原子，Zx代表由1至4个碳原子组成的饱和烷基基团等，Rs代表-D-Rx等，D代表单键、氧原子等，Rx代表由3至8个碳原子组成的饱和烷基基团等，AR代表部分不饱和或完全不饱和的紧凑双环碳环或杂环，Y代表氢原子、由1至4个碳原子组成的低烷基基团等，或其盐。提供了一种具有抑制前列腺素产生和抑制白三烯产生作用的化合物。
• Aromatic reactivity. Part XXXVIII. Protodesilylation of 1,2-dihydrobenzocyclobutene, indan, and tetralin
  作者：A. R. Bassindale、C. Eaborn、D. R. M. Walton

  DOI：10.1039/j29690000012

  日期：——

  Rates of cleavage (protodesilylation) of some trimethylsilyl derivatives of reduced benzocycloalkenes and o-xylene by a mixture of 10·6M-aqueous perchloric acid and methanol (2 : 5 v/v) have been measured spectrophotometrically. Values (min.–1) of the first-order rate constants (×103) at 50·0° are as follows: 3-trimethylsilyl-o-xylene, 193; 4-trimethysilyl-o-xylene, 153; 1,2-dihydro-3-trimethylsilylbenzocyclobutene

  已用分光光度法测定了还原的苯并环烯烃和邻二甲苯的某些三甲基甲硅烷基衍生物被10·6 M高氯酸水溶液和甲醇（2：5 v / v）裂解的速率（原去甲硅烷基化）。在50·0°下的一级速率常数（×10 3）的值（最小值–1）如下：3-三甲基甲硅烷基-邻二甲苯，193；和- （3）。4- trimethysilyl- ö-二甲苯，153; 1,2-二氢-3-三甲基甲硅烷基苯并环丁烯，16·1; 1,2-二氢-4-三甲基甲硅烷基苯并环丁烯，154; 4-三甲基甲硅烷基草酮，77；5-三甲基甲硅烷基草胺，210; 5-三甲基甲硅烷基四氢萘235; 6-三甲基甲硅烷基四氢萘，181。（开环使1,2-二氢苯并环丁烯及其衍生物对亲电试剂行为的大多数研究复杂化，在裂解条件下不会发生。）
• BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX
  申请人：Asaumi Taku

  公开号：US20100184978A1

  公开（公告）日：2010-07-22

  A bipyridine compound represented by the formula (1): wherein R 1 , R 2 and R 3 each independently represent a C1-C10 alkyl group which may be substituted etc., and R 4 , R 5 , R 6 , R 7 and R 8 each independently represent a hydrogen atom etc., a transition metal complex obtained by contacting a bipyridine compound represented by the formula (1) with a compound of a transition metal belonging to Group 9, 10 or 11, and a method for production of a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups are bonded to an aromatic ring with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) being structurally different from the above-mentioned aromatic compound (A) and having one or two leaving groups bonded to an aromatic ring, in the presence of the transition metal complex.

  一种以式(1)表示的联吡啶化合物：其中R1、R2和R3各自独立地表示可以被取代的C1-C10烷基等，而R4、R5、R6、R7和R8各自独立地表示氢原子等，通过将式(1)表示的联吡啶化合物与属于9、10或11族过渡金属的化合物接触而获得的过渡金属配合物，以及一种制备共轭芳香化合物的方法，包括在过渡金属配合物的存在下，将一个或两个离去基团与芳环结合的芳香化合物（A）与具有与上述芳香化合物（A）相同结构的芳香化合物（A）或结构不同于上述芳香化合物（A）且具有一个或两个离去基团与芳环结合的芳香化合物（B）反应。