1,5-二溴-2,3-二甲基苯 | 51209-82-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1,5-二溴-2,3-二甲基苯
• 英文名称: 3,5-dibromo-1,2-dimethyl-benzene
• 英文别名: 3,5-Dibrom-1,2-dimethyl-benzol；1,5-Dibromo-2,3-dimethylbenzene
• CAS: 51209-82-6
• 化学式: C₈H₈Br₂
• 分子量: 263.96
• InChiKey: MUOWYDXIKBTQHA-UHFFFAOYSA-N

物化性质

• 溶解度：
  可溶于氯仿、DMSO（少量）

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,5-二溴-2,3-二甲基苯 在 硝酸 作用下， 生成 1,3-dibromo-4,5-dimethyl-2,6-dinitro-benzene
  参考文献：
  名称：

  Extensive sterile abscess in an invasive fibrous thyroiditis (Riedel’s thyroiditis) caused by an occlusive vasculitis

  摘要：

  Riedel's thyroiditis is a rare disease determined by an invasive fibrosclerotic transformation of the thyroid gland. It may be one manifestation of multifocal fibrosis with still unknown etiology. Because it mimics carcinoma, a biopsy must be performed to get the correct diagnosis. The condition is self-limiting when confined to the neck. Prognosis depends on the extent of extracervical fibrosclerosis. We present a patient with a huge cervical and mediastinal, unilateral thyroid mass expanding to the aortic curve, which led to tracheal deviation and compression with symptoms of strider and dyspnea. These symptoms continued under a course of high-dose steroids; thus an operation was necessary to relieve the airway obstruction and limit inflammation. Intraoperative and pathological findings showed an inflammatory infiltration of the adjacent neck muscles and a sterile abscess caused by an occlusive vasculitis. Therefore, hemithyroidectomy had to be performed instead of a local limited resection. (C)2001, Editrice Kurtis.

  DOI：

  10.1007/bf03343824
• 作为产物：
  描述：

  4,6-二溴-2,3-二甲基苯胺 在 氢溴酸 、 sodium nitrite 作用下， 生成 1,5-二溴-2,3-二甲基苯
  参考文献：
  名称：

  Extensive sterile abscess in an invasive fibrous thyroiditis (Riedel’s thyroiditis) caused by an occlusive vasculitis

  摘要：

  Riedel's thyroiditis is a rare disease determined by an invasive fibrosclerotic transformation of the thyroid gland. It may be one manifestation of multifocal fibrosis with still unknown etiology. Because it mimics carcinoma, a biopsy must be performed to get the correct diagnosis. The condition is self-limiting when confined to the neck. Prognosis depends on the extent of extracervical fibrosclerosis. We present a patient with a huge cervical and mediastinal, unilateral thyroid mass expanding to the aortic curve, which led to tracheal deviation and compression with symptoms of strider and dyspnea. These symptoms continued under a course of high-dose steroids; thus an operation was necessary to relieve the airway obstruction and limit inflammation. Intraoperative and pathological findings showed an inflammatory infiltration of the adjacent neck muscles and a sterile abscess caused by an occlusive vasculitis. Therefore, hemithyroidectomy had to be performed instead of a local limited resection. (C)2001, Editrice Kurtis.

  DOI：

  10.1007/bf03343824

文献信息

• Improved process for side-chain bromination of alkyl-benzenes
  申请人：Helm AG

  公开号：EP1705168A1

  公开（公告）日：2006-09-27

  A process for the side-chain bromination of alkylbenzenes according to Formula (I) wherein R1 is C1-C6-alkyl; R2 is H or C1-C6-alkyl which can be unsubstituted or substituted by one or more cyano groups; R3 is H or C1-C6-alkyl which can be unsubstituted or substituted by one or more cyano groups; comprising the steps of (1) dissolving the compound of Formula (I) in a solvent which is a nonaromatic non-halogenated hydrocarbon which can be substituted by one or more cyano groups; (2) adding a bromination agent selected from the group consisting of Br2 and N-bromoimides to the solution; and optionally (3) agitating the mixture at a temperature within the range of from room temperature to reflux temperature.

  一种用于侧链溴化烷基苯的工艺，根据式（I）其中R1为C1-C6烷基；R2为H或C1-C6烷基，可以未取代或取代一个或多个氰基；R3为H或C1-C6烷基，可以未取代或取代一个或多个氰基；包括以下步骤：（1）将式（I）化合物溶解在一种溶剂中，该溶剂为一种非芳香族非卤代烃，可以取代一个或多个氰基；（2）向溶液中加入从Br2和N-溴代亚胺中选择的溴化试剂；以及可选的（3）在从室温到沸点温度范围内的温度下搅拌混合物。
• Process for side-chain bromination of alkylbenzenes
  申请人：Schulze Michael

  公开号：US20060217569A1

  公开（公告）日：2006-09-28

  A process for the side-chain bromination of alkylbenzenes according to Formula (I) wherein R 1 is C 1 -C 6 -alkyl; R 2 is H or C 1 -C 6 -alkyl which can be unsubstituted or substituted by one or more cyano groups; R 3 is H or C 1 -C 6 -alkyl which can be unsubstituted or substituted by one or more cyano groups; comprising the steps of (1) dissolving the compound of Formula (I) in a solvent which is a non-aromatic non-halogenated hydrocarbon which can be substituted by one or more cyano groups; (2) adding a bromination agent selected from the group consisting of Br 2 and N-bromoimides to the solution; and optionally (3) agitating the mixture at a temperature within the range of from room temperature to reflux temperature.

  一种用于侧链溴化烷基苯的制备的方法，根据式（I）中R1为C1-C6-烷基；R2为H或C1-C6-烷基，可以是未取代或取代一个或多个氰基；R3为H或C1-C6-烷基，可以是未取代或取代一个或多个氰基；包括以下步骤：（1）将式（I）化合物溶解在一种溶剂中，所述溶剂为一种非芳香族非卤代烃，可以被一个或多个氰基取代；（2）向溶液中加入从Br2和N-溴代亚胺中选择的溴化剂；可选地（3）在室温至沸点温度范围内搅拌混合物。
• Azoline Compounds for Combating Arthropod Pests
  申请人：Koradin Christopher

  公开号：US20100010058A1

  公开（公告）日：2010-01-14

  The present invention relates to azoline compounds and their salts which are useful for combating arthropod pests. The present invention also relates to a method for combating arthropod pests and to agricultural compositions for combating said pests. It has been found that these objectives can be achieved by azoline compounds of the general formulae Ia or Ib, wherein X is S, O or NR 4 ; Ar is phenyl or a 5 or 6 membered heteroaromatic ring; R 1 is H, C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, phenyl, a heteroaromatic ring etc.; R 2a , R 2b are H, CN, C 1 -C 6 -alkyl etc.; R 1 together with R 2a may also form a linear C 2 -C 4 -alkandiyl; R 3a-d are H, halogen, C 1 -C 6 -alkyl etc.

  本发明涉及用于对抗节肢动物害虫的噁唑啉化合物及其盐。本发明还涉及一种对抗节肢动物害虫的方法和用于对抗上述害虫的农业组合物。已经发现，通过通式Ia或Ib的噁唑啉化合物可以实现这些目标，其中X为S、O或NR4；Ar为苯基或5或6成员杂芳环；R1为H、C1-C6烷基、C2-C6烯基、苯基、杂芳环等；R2a、R2b为H、CN、C1-C6烷基等；R1与R2a还可以形成线性C2-C4烷二基；R3a-d为H、卤素、C1-C6烷基等。
• Organic electroluminescent element material, organic electroluminescent element, display device and lighting device
  申请人：Ikemizu Dai

  公开号：US20070196690A1

  公开（公告）日：2007-08-23

  An organic electroluminescent element material represented by Formula (1), Formula (1): wherein Z is a heterocylcic ring comprising a substituent having a steric parameter value (Es) of −0.5 or less at the third atom of the ring counted from a nitrogen atom attached to Z, the nitrogen atom being counted as the first atom; and other symbols in Formula (1) are described in the specification.

  一种由式（1）表示的有机电致发光元件材料，式（1）：其中Z是一个杂环环，包括一个取代基，在从Z连接的氮原子算起的第三个原子处具有空间参数值（Es）小于或等于-0.5，该氮原子被计为第一个原子；式（1）中的其他符号在说明书中描述。
• Pesticidal Compositions
  申请人：Kordes Markus

  公开号：US20080312085A1

  公开（公告）日：2008-12-18

  The present invention relates to 1-(Azolin-2-yl)-amino-alkane compounds, which are useful for combating insects, arachnids and nematodes. The present invention also relates to a method for combating animal pests selected from insects, arachnids and nematodes, and to agricultural compositions for combating animal pests. It has been found that animal pests can be combated by 1-(Azolin-2-yl)-amino-alkane compounds of the general formula I: wherein A is a radical of the formulae A 1 or A 2 : and wherein X is sulfur or oxygen and W, B and R 1 to R 6 are defined as in the description.

  本发明涉及1-(Azolin-2-yl)-amino-烷基化合物，其可用于对抗昆虫、蜘蛛和线虫。本发明还涉及一种用于对抗昆虫、蜘蛛和线虫等动物害虫的方法，以及用于对抗动物害虫的农业组合物。发现可以通过通式I中的1-(Azolin-2-yl)-amino-烷基化合物对动物害虫进行对抗，其中A是式A1或A2的基团：X是硫或氧，W、B和R1至R6如描述中所定义。