1-(4'-chloromethylphenyl)-1-(2'',2'',6'',6''-tetra-methyl-1-piperidinyloxy)ethyl | 212132-38-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(4'-chloromethylphenyl)-1-(2'',2'',6'',6''-tetra-methyl-1-piperidinyloxy)ethyl
• 英文别名: 1-(4'-chloromethylphenyl)-1-(2'',2'',6'',6''-tetramethyl-1-piperidinyloxy)ethyl；N-[p-(chloromethyl)-α-methylbenzyloxy]-2,2,6,6-tetramethylpiperidine；1-(1-(4-(Chloromethyl)phenyl)ethoxy)-2,2,6,6-tetramethylpiperidine；1-[1-[4-(chloromethyl)phenyl]ethoxy]-2,2,6,6-tetramethylpiperidine
• CAS: 212132-38-2
• 化学式: C₁₈H₂₈ClNO
• 分子量: 309.879
• InChiKey: SQIBFIFOLCKDOG-UHFFFAOYSA-N

物化性质

• 沸点：
  380.1±44.0 °C(Predicted)
• 密度：
  1.05±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-hydroxymethylene-1,3-phenylene-1',3'-phenylene-32-crown-10 、 1-(4'-chloromethylphenyl)-1-(2'',2'',6'',6''-tetra-methyl-1-piperidinyloxy)ethyl 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 以75%的产率得到1-[1-[4-(2,5,8,11,14,20,23,26,29,32-Decaoxatricyclo[31.3.1.115,19]octatriaconta-1(37),15(38),16,18,33,35-hexaen-17-ylmethoxymethyl)phenyl]ethoxy]-2,2,6,6-tetramethylpiperidine
  参考文献：
  名称：

  定义明确的冠封端聚合物的合成和模型络合研究

  摘要：

  基于TEMPO-A自由基引发剂（4a中含有）二苯并-24-冠-8（DB24C8，图2a）部分的合成。类似的引发剂（图4b基于双）（米-亚苯基）-32-冠-10（BMP32C10，1B）还合成。基于冠的引发剂用于制备分子量分布窄（PDI）的冠醚封端的聚苯乙烯。已证明以DB24C8为末端的聚合物5与六氟磷酸二苄基铵（17）形成假轮烷络合物（18），但是由于其空腔小，所以5不能络合大体积的N，N。'-二烷基-4,4'-联吡啶鎓（百草枯或紫精）盐。在另一方面，所述BMP32C10封端的聚合物11络合N，N-双（p -叔丁基苄基）-4,4'-二吡啶鎓二（六氟磷酸盐（百草枯盐，23）强烈，但没有与相互作用六氟磷酸二苄（17）到可检测的程度。因此，这些新的聚合物主体是使用拟轮烷络合的超分子化学的大分子构建基，并且两者均显示出选择性。DB24C8聚合物对仲铵离子络合具有选择性，而BMP32C20聚合物对百

  DOI：

  10.1021/ma047811y
• 作为产物：
  描述：

  2,2,6,6-四甲基哌啶氧化物 、 4-氯甲基苯乙烯 在 sodium tetrahydroborate 、 N,N’-双(亚水杨基)-1,2-乙二胺-锰(II) 、 二叔丁基过氧化物 作用下， 以 乙醇 、 甲苯 为溶剂， 以20%的产率得到1-(4'-chloromethylphenyl)-1-(2'',2'',6'',6''-tetra-methyl-1-piperidinyloxy)ethyl
  参考文献：
  名称：

  Multi-armed, TEMPO-functionalized unimolecular initiators for starburst dendrimer synthesis via stable free radical polymerisation. 2. Tris (1,3,5)benzyloxy unimers

  摘要：

  描述了三官能TEMPO修饰的单分子引发剂unimers I、II和III的合成。通过1,3,5-三(iodomethyl)苯与含有TEMPO的乙基苯羟基衍生物进行SN2型Williamson醚偶联来制备Unimer I。然而，Unimer II的合成是通过1,3,5-三(bromomethyl)苯与含有羟基乙基苯TEMPO衍生物在三氟乙酸银存在下进行SN1反应实现的。Unimer III的合成始于phloroglucinol和与1-氟-4-硝基苯进行SNAr反应，随后还原为氨基化合物并与TEMPO衍生的芳香醛形成席夫碱。还描述了使用Unimer I对苯乙烯和乙酰氧基苯乙烯进行稳定自由基聚合（SFRP），并报告了分子量和多分散性。总结认为，使用三重自由基引发剂对苯乙烯进行SFRP符合活性体系的要求。关键词：稳定自由基聚合，星芒状树脂，多臂单分子引发剂。

  DOI：

  10.1139/v04-106

文献信息

• Stimuli responsive surfaces through recognition-mediated polymer modification
  作者：Hao Xu、Tyler B. Norsten、Oktay Uzun、Eunhee Jeoung、Vincent M. Rotello

  DOI：10.1039/b509572g

  日期：——

  Specific three-point hydrogen bonding between diamidopyridine (DAP) and thymine (Thy) was employed to reversibly anchor “brush-like” Tri-DAP end-functionalized polystyrene onto Thy-modified silica surfaces.

  利用二氨基吡啶（DAP）和胸腺嘧啶（Thy）之间特定的三点氢键，可逆地将 "刷状 "Tri-DAP末端官能化聚苯乙烯锚定在Thy修饰的二氧化硅表面上。
• Water soluble multi-walled carbon nanotubes prepared via nitroxide-mediated radical polymerization
  作者：Xiaodong Zhao、Weiran Lin、Naiheng Song、Xiaofang Chen、Xinghe Fan、Qifeng Zhou

  DOI：10.1039/b609431g

  日期：——

  Nitroxide-mediated radical polymerizations of 4-vinylpyridine and sodium 4-styrenesulfonate were carried out on the surfaces of MWNT to afford poly(4-vinylpyridine)-grafted MWNT (MWNT-P4VP) and poly(sodium 4-styrenesulfonate)-grafted MWNT (MWNT-PSS). The covalent bonding of polymers to the MWNT surface was confirmed by IR and TGA investigations. SEM, TEM and AFM investigations also showed a polymer-wrapped MWNT structure. Due to the presence of basic pyridine units in the structures, MWNT-P4VP exhibited good solubility in acidic aqueous solutions, but tended to aggregate in neutral or basic solutions. In comparison, MWNT-PSS could form stable dispersion solutions in aqueous solutions throughout the pH range from 1 to 14.

  在MWNT表面进行了4-乙烯基吡啶和4-苯乙烯磺酸钠的硝基自由基聚合，得到聚（4-乙烯基吡啶）接枝MWNT（MWNT-P4VP）和聚（4-苯乙烯磺酸钠）接枝MWNT（MWNT-PSS）。通过红外光谱和热重分析证实了聚合物与MWNT表面的共价键合。扫描电子显微镜、透射电子显微镜和原子力显微镜的研究也表明了聚合物包裹的MWNT结构。由于结构中存在碱性吡啶单元，MWNT-P4VP在酸性水溶液中具有良好的溶解性，但在中性或碱性溶液中容易聚集。相比之下，MWNT-PSS可以在pH值为1至14的水溶液中形成稳定的分散溶液。
• RANDOM COPOLYMER FOR FORMING NEUTRAL SURFACE AND METHODS OF MANUFACTURING AND USING THE SAME
  申请人：KANG Min-Hyuck

  公开号：US20120273460A1

  公开（公告）日：2012-11-01

  A random copolymer having a structure represented by the following Formula 1: wherein R is phosphonic acid, Me is a methyl group, x is a number of styrene units, and y is a number of methyl methacrylate units.

  一种随机共聚物的结构式如下所示：式中R为膦酸，Me为甲基，x为苯乙烯单元数，y为甲基丙烯酸甲酯单元数。
• Random copolymer for forming neutral surface and methods of manufacturing and using the same
  申请人：Kang Min-Hyuck

  公开号：US08653211B2

  公开（公告）日：2014-02-18

  A random copolymer having a structure represented by the following Formula 1: wherein R is phosphonic acid, Me is a methyl group, x is a number of styrene units, and y is a number of methyl methacrylate units.

  一种随机共聚物的结构如下式1所示：其中R代表膦酸，Me代表甲基，x代表苯乙烯单元数，y代表甲基丙烯酸甲酯单元数。
• Effects of Dendron Generation and Salt Concentration on Phase Structures of Dendritic–Linear Block Copolymers with a Semirigid Dendron Containing PEG Tails
  作者：Huanhuan Cai、Guoliang Jiang、Zhihao Shen、Xinghe Fan

  DOI：10.1021/ma300654j

  日期：2012.8.14

  We prepared a series of dendritic linear block copolymers (DLBCPs) bearing a semirigid Percec-type dendron with ionophilic poly(ethylene glycol) (PEG) tails and a polystyrene (PS) linear polymer by nitroxide-mediated living radical polymerization (NMRP). As the DLBCPs are connected by an ester linkage, through hydrolysis the molecular weights of the DLBCPs were precisely characterized by gel permeation chromatography and MALDI-TOF MS. Differential scanning calorimetry, small-angle X-ray scattering, and transmission electron microscopy were used to investigate the phase behaviors of the DLBCPs. Results show that the PEG tails of the semirigid dendron display a cold crystallization peak and a melting peak during the second heating process, while for the neat DLBCPs, the crystallization of the PEG tails is completely inhibited, and only the glass transition temperature (T-g) of the PS block is observed. However, T-g of the dendron block can be observed by complexing the DLBCPs with LiCF3SO3, suggesting that microphase separation occurs in the doped DLBCPs. Comparing the phase behaviors of the DLBCPs having the same dendron weight fraction (w(D) = 0.14) with varying dendron generation and salt concentration, we found that the G(1) or G(2) DLBCP undergoes a phase transition from a hexagonally packed cylinder structure to a lamellar structure with increasing content of LiCF3SO3. However, the G(3) DLBCP only displays a lamellar phase, and the lamellar thickness increases with increasing salt concentration. The difference can be attributed to the different degree of chain branching, which leads to different interface curvature.