4-(tert-buthyl-diphenyl-silanyloxy)-3-methoxy-phenyl-boronic acid | 482309-54-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-(tert-buthyl-diphenyl-silanyloxy)-3-methoxy-phenyl-boronic acid
• 英文别名: (4-{[tert-Butyl(diphenyl)silyl]oxy}-3-methoxyphenyl)boronic acid；[4-[tert-butyl(diphenyl)silyl]oxy-3-methoxyphenyl]boronic acid
• CAS: 482309-54-6
• 化学式: C₂₃H₂₇BO₄Si
• 分子量: 406.361
• InChiKey: ZSPFICKKGHQCFL-UHFFFAOYSA-N

物化性质

• 沸点：
  511.3±60.0 °C(Predicted)
• 密度：
  1.14±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.31
• 重原子数：
  29
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-(tert-buthyl-diphenyl-silanyloxy)-3-methoxy-phenyl-boronic acid 、 2-碘苯胺 在 palladium diacetate potassium carbonate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 20.0h， 生成 4'-(tert-butyl-diphenyl-silanyloxy)-3'-methoxy-biphenyl-2-ylamine
  参考文献：
  名称：

  [EN] N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES
  [FR] AMIDE D'ACIDE N-BISARYL- ET N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY- ET ALPHA-ALCOXY

  摘要：

  该发明涉及一般式（I）的N-双芳基和N-芳基环烷基亚羟基和亚烷氧基乙酸酰胺，包括其光学异构体和这些异构体的混合物，其中R1为氢、C1-C12烷基；C2-C12烯基；C2-C12炔基；C1-C12卤代烷基；R2为氢；可选择地取代的烷基；可选择地取代的烯基或可选择地取代的炔基；R3为可选择地取代的芳基或可选择地取代的杂芳基；A为可选择地取代的饱和或不饱和的C3-C8环烷基亚甲基，可选择地取代的苯亚甲基或可选择地取代的饱和或不饱和的杂环烷基亚甲基桥，R4和R5各自独立地为氢或有机基，R6为氢；三C1-C4烷基硅基；二C1-C4烷基苯基硅基；C1-C4烷基二苯基硅基；三苯基硅基；可选择地取代的烷基；可选择地取代的烯基或可选择地取代的炔基。这些化合物具有植物保护性能，适用于保护植物免受植物病原微生物，特别是真菌的侵害。

  公开号：

  WO2004011417A1
• 作为产物：
  描述：

  硼酸三异丙酯 、 4-(tert-butyldiphenylsilanoxy)-3-methoxybromobenzene 在 正丁基锂 、 盐酸 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 1.5h， 生成 4-(tert-buthyl-diphenyl-silanyloxy)-3-methoxy-phenyl-boronic acid
  参考文献：
  名称：

  [EN] N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES
  [FR] AMIDE D'ACIDE N-BISARYL- ET N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY- ET ALPHA-ALCOXY

  摘要：

  该发明涉及一般式（I）的N-双芳基和N-芳基环烷基亚羟基和亚烷氧基乙酸酰胺，包括其光学异构体和这些异构体的混合物，其中R1为氢、C1-C12烷基；C2-C12烯基；C2-C12炔基；C1-C12卤代烷基；R2为氢；可选择地取代的烷基；可选择地取代的烯基或可选择地取代的炔基；R3为可选择地取代的芳基或可选择地取代的杂芳基；A为可选择地取代的饱和或不饱和的C3-C8环烷基亚甲基，可选择地取代的苯亚甲基或可选择地取代的饱和或不饱和的杂环烷基亚甲基桥，R4和R5各自独立地为氢或有机基，R6为氢；三C1-C4烷基硅基；二C1-C4烷基苯基硅基；C1-C4烷基二苯基硅基；三苯基硅基；可选择地取代的烷基；可选择地取代的烯基或可选择地取代的炔基。这些化合物具有植物保护性能，适用于保护植物免受植物病原微生物，特别是真菌的侵害。

  公开号：

  WO2004011417A1

文献信息

• N-bisaryl- and n-aryl-cylcloakylidenyl-alpha-hydroxy-and alpha-alkoxy acid amides
  申请人：Lamberth Clemens

  公开号：US20050245607A1

  公开（公告）日：2005-11-03

  The invention relates to N-bisaryl- and N-aryl-cycloalkylidenyl-a-hydroxy- and a-alkoxy acetic acid amides of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R 1 is hydrogen, C 1 -C 12 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkynyl; C 1 -C 12 haloalkyl; R 2 is hydrogen; optionally substituted alkyl; optionally substituted alkenyl or optionally substituted alkynyl; R 3 is optionally substituted aryl or optionally substituted heteroaryl; A is an optionally substituted saturated or unsaturated C 3 -C 8 -cycloalkylidene, optionally substituted phenylidene or optionally substituted saturated or unsaturated heterocyclylidene bridge, R 4 and R 5 are each independently hydrogen or an organic radical, and R 6 is hydrogen; tri-C 1 -C 4 alkyl-silyl; di-C 1 -C 4 alkyl-phenylsilyl; C 1 -C 4 alkyl-diphenylsilyl; triphenylsilyl; optionally substituted alkyl; optionally substituted alkenyl or optionally substituted alkynyl. The compounds possess plant-protecting properties and are suitable for protecting plants against infestation by phytopathogenic miroorganism, especially fungi.

  本发明涉及一般式（I）的N-双芳基和N-芳基环烷基亚羟基和亚烷氧基乙酸酰胺，包括其光学异构体和混合物，其中R1为氢、C1-C12烷基；C2-C12烯基；C2-C12炔基；C1-C12卤代烷基；R2为氢；可选取代的烷基；可选取代的烯基或可选取代的炔基；R3为可选取代的芳基或可选取代的杂芳基；A为可选取代的饱和或不饱和C3-C8环烷基亚甲基、可选取代的苯亚甲基或可选取代的饱和或不饱和杂环亚甲基桥；R4和R5各自独立地为氢或有机基团，R6为氢；三C1-C4烷基硅基；二C1-C4烷基苯基硅基；C1-C4烷基二苯基硅基；三苯基硅基；可选取代的烷基、可选取代的烯基或可选取代的炔基。该化合物具有植物保护性能，适用于保护植物免受植物病原微生物（特别是真菌）的侵害。
• Novel n-bisaryl- and n-aryl-cycloalkylidenyl-alpha-sulfin- and alpha-sulfonamino acid amides
  申请人：——

  公开号：US20040214721A1

  公开（公告）日：2004-10-28

  The invention relates to novel pesticidally active N-bisaryl-and N-aryl-cycloalkylidenyl-&agr;-sulfin-and &agr;-sulfonamino acid amides of the general formula I, including the optical isomers thereof and mixtures of such isomers, wherein n is a number zero or one; R 1 is C 1 -C 12 alkyl; C 1 -C 12 alkyl substituted with C 1 -C 4 alkoxy, C 1 -C 4 alkylthio, C 1 -C 4 alkylsulfonyl, C 3 -C 8 cycloalkyl, cyano, C 1 -C 6 alkoxycarbonyl, C 3 -C 6 alkoxycarbonyl, C 3 -C 6 alkenyloxycarbonyl or C 3 -C 6 alkynyloxycarbonyl; C 2 -C 12 alkenyl; C 2 -C 12 alkynyl; C 1 -C 12 haloalkyl; or a group NR 11 R 12 wherein R 11 and R 12 are each independently of the other C 1 -C 6 alkyl, or together are tetra- or penta-methylene; R 2 and R 3 ae each independently hydrogen; C 1 -C 8 alkyl; C 1 -C 8 alkyl substituted with hydroxy, mercapto, C 1 -C 4 alkoxy or C 1 -C 4 alkylthio; C 3 -C 8 alkenyl; C 3 -C 8 alkynyl; C 3 -C 8 cycloalkyl; C 3 -C 8 cycloalkyl-C 1 -C 4 alkyl; optionally substituted aryl; optionally substituted heteroaryl; or the two groups R 2 and R 3 together with the carbon atom to which they are bonded form a three- to eight-membered hydrocarbon ring; A is an optionally substituted saturated or unsaturated C 3 -C 8 -cycloalkylidene, optionally substituted phenylidene or optionally substituted saturated or unsaturated heterocyclylidene bridge, R 4 and R 5 are each independently hydrogen or an organic radicak, and R 6 is hydrogen; tri-C 1 C 4 alkyl-silyl; di-C 1 -C 4 alkyl-phenysilyl; C 1 -C 4 alkyl-diphenylsilyl; tri-phenylsilyl; optionally subsituted alkyl; optionally substituted alkenyl or optionally substituted alkynyl. The novel compounds possess plant-protecting properties and are suitable for protecting plants against infestation by phytophathogenic microorganisms. 1

  本发明涉及一种新型杀虫活性的一般式I的N-双芳基和N-芳基环烷基亚磺酰和亚磺酸氨基酸酰胺，包括其光学异构体和这些异构体的混合物，其中n是0或1; R1是C1-C12烷基; C1-C12烷基被C1-C4烷氧基、C1-C4烷基硫基、C1-C4烷基磺酰基、C3-C8环烷基、氰基、C1-C6烷氧羰基、C3-C6烷氧羰基、C3-C6烯氧羰基或C3-C6炔氧羰基取代; C2-C12烯基; C2-C12炔基; C1-C12卤代烷基; 或者NR11R12基团，其中R11和R12各自独立地是C1-C6烷基，或者一起是四亚甲基或五亚甲基; R2和R3各自独立地是氢; C1-C8烷基; C1-C8烷基被羟基、巯基、C1-C4烷氧基或C1-C4烷基硫基取代; C3-C8烯基; C3-C8炔基; C3-C8环烷基; C3-C8环烷基-C1-C4烷基; 可选取代的芳基; 可选取代的杂环芳基; 或者R2和R3两个基团与它们所连接的碳原子一起形成三到八元环烃环; A是可选取代的饱和或不饱和的C3-C8环烷基亚甲基，可选取代的苯亚甲基或可选取代的饱和或不饱和的杂环亚甲基桥，R4和R5各自独立地是氢或有机基团，R6是氢; 三C1-C4烷基硅基; 二C1-C4烷基苯基硅基; C1-C4烷基二苯基硅基; 三苯基硅基; 可选取代的烷基; 可选取代的烯基或可选取代的炔基。这些新化合物具有植物保护性能，适用于保护植物免受植物病原微生物的侵害。
• N-bisaryl- and n-aryl-cycloakylidenyl-αhydroxy-and α-alkoxy acid amides
  申请人：Syngenta Crop Protection, Inc.

  公开号：US07166746B2

  公开（公告）日：2007-01-23

  The invention relates to N-bisaryl- and N-aryl-cycloalkylidenyl-a-hydroxy- and a-alkoxy acetic acid amides of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R1 is hydrogen, C1–C12alkyl; C2–C12alkenyl; C2–C12alkynyl; C1–C12haloalkyl; R2 is hydrogen; optionally substituted alkyl; or optionally substituted alkynyl; R3 is optionally substituted aryl or optionally substituted heteroaryl; A is an optionally substituted saturated or unsaturated C3–C8-cycloalkylidene, optionally substituted phenylidene or optionally substituted saturated or unsaturated heterocyclylidene bridge, R4 and R5 are each independently hydrogen or an organic radical, and R6 is hydrogen; tri-C1–C4alkyl-silyl; di-C1–C4alkyl-phenylsilyl; C1–C4alkyl-diphenylsilyl; triphenylsilyl; optionally substituted alkyl; optionally substituted alkenyl or optionally substituted alkynyl. The compounds possess plant-protecting properties and are suitable for protecting plants against infestation by phytopathogenic microorganism, especially fungi.

  本发明涉及一般式（I）的N-双芳基和N-芳基环烷基烯基-a-羟基和a-烷氧基乙酸酰胺，包括其光学异构体和混合物，其中R1为氢，C1-C12烷基；C2-C12烯基；C2-C12炔基；C1-C12卤代烷基；R2为氢；可选取代烷基；或可选取代炔基；R3为可选取代芳基或可选取代杂环芳基；A为可选取代饱和或不饱和C3-C8环烷基亚甲基，可选取代苯亚甲基或可选取代饱和或不饱和杂环亚甲基桥，R4和R5各自独立地为氢或有机基团，R6为氢；三C1-C4烷基硅基；二C1-C4烷基苯基硅基；C1-C4烷基二苯基硅基；三苯基硅基；可选取代烷基；可选取代烯基或可选取代炔基。这些化合物具有植物保护性能，适用于保护植物免受植物病原微生物，特别是真菌的侵害。