N-dodecyl-N-methyl-p-toluenesulfonamide | 1208109-20-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-dodecyl-N-methyl-p-toluenesulfonamide
• 英文别名: N-dodecyl-N,4-dimethylbenzenesulfonamide
• CAS: 1208109-20-9
• 化学式: C₂₀H₃₅NO₂S
• 分子量: 353.569
• InChiKey: GPAALTKLDFVVET-UHFFFAOYSA-N

物化性质

• 沸点：
  455.5±38.0 °C(Predicted)
• 密度：
  1.002±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  24
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-dodecyl-N-methyl-p-toluenesulfonamide 在 萘 、 四乙基溴化铵 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以82%的产率得到N-十二烷基甲胺
  参考文献：
  名称：

  Hg cathode-free electrochemical detosylation of N,N-disubstituted p-toluenesulfonamides: mild, efficient, and selective removal of N-tosyl group

  摘要：

  Hg cathode-free electrochemical detosylation of N,N-disubstituted p-toluenesulfonamides was successfully carried out by a constant Current electrolysis using an undivided cell equipped with a platinum cathode and a magnesium anode in the presence of an arene mediator. The deprotection proceeded efficiently and selectively under neutral and mild conditions with a stoichiometric amount of electricity without the use of an Hg cathode to obtain the corresponding secondary amines in good to excellent yields. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.11.056
• 作为产物：
  描述：

  N-十二烷基对甲苯磺酰胺 、 碘甲烷 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以90%的产率得到N-dodecyl-N-methyl-p-toluenesulfonamide
  参考文献：
  名称：

  Hg cathode-free electrochemical detosylation of N,N-disubstituted p-toluenesulfonamides: mild, efficient, and selective removal of N-tosyl group

  摘要：

  Hg cathode-free electrochemical detosylation of N,N-disubstituted p-toluenesulfonamides was successfully carried out by a constant Current electrolysis using an undivided cell equipped with a platinum cathode and a magnesium anode in the presence of an arene mediator. The deprotection proceeded efficiently and selectively under neutral and mild conditions with a stoichiometric amount of electricity without the use of an Hg cathode to obtain the corresponding secondary amines in good to excellent yields. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.11.056

文献信息

• Method of making polymeric particles
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0653442A2

  公开（公告）日：1995-05-17

  A method of making polymeric particles by forming a suspension of ethylenically unsaturated monomer droplets in water, the water containing a particulate suspension agent, the monomer droplets containing a nonreactive hydrophobic compound where the water solubility of the nonreactive compound is less than that of the monomer and polymerizing the monomer droplets.

  一种通过在水中形成乙烯基不饱和单体液滴悬浮液来制造聚合物微粒的方法，水中含有微粒悬浮剂，单体液滴中含有非反应性疏水化合物，其中非反应性化合物的水溶性小于单体的水溶性，并使单体液滴聚合。
• The process for making photographic polymeric matte bead particles
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0709399A2

  公开（公告）日：1996-05-01

  A process of making polymeric matte bead particles for use in photographic elements which comprises forming a suspension of ethylenically unsaturated monomer droplets in an aqueous media, subsequent to the formation of droplets and before commencement of reaction, adding to the aqueous media an effective amount of a hydrophilic colloid to improve adhesion and polymerizing the monomer to form solid polymeric particles.

  一种用于摄影元件的聚合消光珠粒子的制造工艺，包括在水介质中形成乙烯不饱和单体液滴悬浮液，在液滴形成后和反应开始前，向水介质中加入有效量的亲水胶体以提高粘附性，并使单体聚合形成固体聚合粒子。
• US5455320A
  申请人：——

  公开号：US5455320A

  公开（公告）日：1995-10-03
• US5492960A
  申请人：——

  公开号：US5492960A

  公开（公告）日：1996-02-20
• US5563226A
  申请人：——

  公开号：US5563226A

  公开（公告）日：1996-10-08