4-(4-nitro-phenyl)-[2,2']bipyridinyl | 477566-94-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-(4-nitro-phenyl)-[2,2']bipyridinyl
• 英文别名: 4-(4-nitrophenyl)-2,2'-bipyridine；4-(4-Nitrophenyl)-2,2'-bipyridine；4-(4-nitrophenyl)-2-pyridin-2-ylpyridine
• CAS: 477566-94-2
• 化学式: C₁₆H₁₁N₃O₂
• 分子量: 277.282
• InChiKey: DQAMUCODWQGKPC-UHFFFAOYSA-N

物化性质

• 沸点：
  457.0±35.0 °C(Predicted)
• 密度：
  1.270±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  71.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-(4-nitro-phenyl)-[2,2']bipyridinyl 在 palladium 10% on activated carbon 、 一水合肼 作用下， 以 乙醇 为溶剂， 反应 2.0h， 以83%的产率得到4-(4-aminophenyl)-2,2'-bipyridine
  参考文献：
  名称：

  Photophysical and biological investigation of novel luminescent Ru(ii)-polypyridyl-1,8-naphthalimide Tröger's bases as cellular imaging agents

  摘要：

  描述了两种 Ru(II)-聚吡啶基 1,8-萘二甲酰亚胺 Tröger 碱 1 和 2 的合成和光物理性质；研究发现它们可以稳定双链 DNA，快速被细胞吸收，即使在孵育 24 小时后也能显示良好的发光而不影响细胞活力。

  DOI：

  10.1039/c2cc17274g
• 作为产物：
  描述：

  3-(4-硝基苯基)-1-(2-吡啶基)-2-丙烯酮 在 yttrium(III) hexafluoroacetylacetonate 盐酸羟胺 作用下， 以 四氢呋喃 、 乙腈 为溶剂， 反应 6.0h， 生成 4-(4-nitro-phenyl)-[2,2']bipyridinyl
  参考文献：
  名称：

  Synthesis of mono-substituted 2,2′-bipyridinesElectronic supplementary information (ESI) available: experimental details and full characterization of new compounds. See http://www.rsc.org/suppdata/cc/b2/b203595b/

  摘要：

  快速合成4-芳基-2,2'-联吡啶的方法被描述，该方法不仅有效制备了一些先前报道过的化合物并且还得到了一些新型功能化联吡啶，产率均较高。

  DOI：

  10.1039/b203595b

文献信息

• Photophysical and biological investigation of novel luminescent Ru(ii)-polypyridyl-1,8-naphthalimide Tröger's bases as cellular imaging agents
  作者：Robert B. P. Elmes、Marialuisa Erby、Sandra A. Bright、D. Clive Williams、Thorfinnur Gunnlaugsson

  DOI：10.1039/c2cc17274g

  日期：——

  The synthesis and photophysical properties of 1 and 2, two Ru(II)-polypyridyl based-1,8-naphthalimide Tröger's bases, are described; these were found to stabilize double stranded DNA, undergo rapid cellular uptake, displaying good luminescence without affecting cell viability even after 24 hours of incubation.

  描述了两种 Ru(II)-聚吡啶基 1,8-萘二甲酰亚胺 Tröger 碱 1 和 2 的合成和光物理性质；研究发现它们可以稳定双链 DNA，快速被细胞吸收，即使在孵育 24 小时后也能显示良好的发光而不影响细胞活力。
• Electrochemiluminescence Self-Interference Spectroscopy with Vertical Nanoscale Resolution
  作者：Yafeng Wang、Weiliang Guo、Qian Yang、Bin Su

  DOI：10.1021/jacs.9b12833

  日期：2020.1.22

  Here we report an electrochemiluminescence (ECL) self-interference spectroscopy technique (designated as ECLIS) with spatial resolution in the normal direction of the electrode surface. Self-interference principally originates from the superposition of ECL emitted directly by luminophores and that reflected from electrode surfaces, resulting in a spectrum consisting of orderly distributed peaks. On the basis of this spectrum and theoretical analysis by the matrix propagation model, the distance between luminophores and the electrode surface can be probed with a vertical resolution on the nanometer scale. We demonstrated first in this work that the height of ECL luminophores assembled on the electrode surface using different molecular linkers, such as double-stranded DNA, could be determined, as well as the possible conformation of linker molecules at the surface. Moreover, the thickness of the ECL emitting layer adjacent to the electrode surface was estimated for the classical coreactant ECL systems involving freely diffusing Ru(bpy)(3)(2+) and tri-n-propylamine in solutions. The thickness was found to vary from similar to 350 nm to nearly 1 mu m depending on the concentration of Ru(bpy)(3)(2+). We believe that ECLIS with a high vertical resolution will provide an easy way to collect molecular conformation information and study ECL reaction mechanisms at electrode interfaces.
• Synthesis of mono-substituted 2,2′-bipyridinesElectronic supplementary information (ESI) available: experimental details and full characterization of new compounds. See http://www.rsc.org/suppdata/cc/b2/b203595b/
  作者：Joseph G. Cordaro、James K. McCusker、Robert G. Bergman

  DOI：10.1039/b203595b

  日期：2002.7.1

  The rapid synthesis of 4-aryl-2,2′-bipyridines is described leading to some previously reported compounds in good yields in addition to some new functionalized bipyridines.

  快速合成4-芳基-2,2'-联吡啶的方法被描述，该方法不仅有效制备了一些先前报道过的化合物并且还得到了一些新型功能化联吡啶，产率均较高。
• New Spectroelectrochemical Insights into Manganese and Rhenium Bipyridine Complexes as Catalysts for the Electrochemical Reduction of Carbon Dioxide
  作者：Alice Barbero、Laura Rotundo、Chiara Reviglio、Roberto Gobetto、Romana Sokolova、Jan Fiedler、Carlo Nervi

  DOI：10.3390/molecules28227535

  日期：——

  (SEC), a technique that combines IR spectroscopy with electrochemistry. Four different Mn and Re catalysts for electrochemical CO2 reduction were studied in dry acetonitrile. In the case of Mn(apbpy)(CO)3Br (apbpy = 4(4-aminophenyl)-2,2'-bipyridine), SEC suggested that a very slow catalytic reduction of CO2 also occurs in acetonitrile in the absence of proton donors, but at rather negative potentials

  本研究旨在利用红外光谱电化学（SEC）（一种将红外光谱与电化学相结合的技术）来展示不同配合物的行为。研究了四种不同的 Mn 和 Re 催化剂，用于在无水乙腈中进行电化学 CO2 还原。对于 Mn(apbpy)(CO)3Br（apbpy = 4(4-氨基苯基)-2,2'-联吡啶），SEC 表明，在没有质子供体的情况下，乙腈中也会发生非常缓慢的 CO2 催化还原，但电位相当负。相比之下，相应的 Re(apbpy)(CO)3Br 在第一次还原电位下明显表现出缓慢的催化转化。改用乙腈和 5% 水的混合物中的饱和 CO2 溶液作为质子供体，Mn(apbpy)(CO)3Br 的 SEC 显示出更快的催化行为。