2-(4-戊烯)丙二酸 | 4475-07-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-(4-戊烯)丙二酸
• 英文名称: 2-(Penten-5-yl)malonic acid
• 英文别名: 2-Carboxy-hept-6-ensaeure；pent-4-enyl-malonic acid；Pent-4-enyl-malonsaeure；Hexen-(5)-dicarbonsaeure-(1.1)；2-(Pent-4-enyl)malonic acid；2-pent-4-enylpropanedioic acid
• CAS: 4475-07-4
• 化学式: C₈H₁₂O₄
• 分子量: 172.181
• InChiKey: JWUROHSCXFTCEX-UHFFFAOYSA-N

物化性质

• 沸点：
  344.6±30.0 °C(Predicted)
• 密度：
  1.184±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2917190090

反应信息

• 作为反应物：
  描述：

  2-(4-戊烯)丙二酸 生成 6-庚烯酸
  参考文献：
  名称：

  银（I）与烯键的配位。钴（II），镍（II），铜（II），锌（II），镉（II）和银（I）与乙酸和亚氨基二乙酸的一些不饱和衍生物之间的络合物形成

  摘要：

  多个取代的丙二酸RCH（CO 2 H）2，乙酸RCH 2 CO 2 H和亚氨基二乙酸RN（CH 2 CO 2 H）2。合成了含有结合有烯键的取代基的化合物（R ＝ CH 2：CH·CH 2，CH 2：CH·CH 2 ·CH 2和CH 2：CH·CH 2 ·CH 2 ·CH 2），其形成常数与H +，Co 2 +，Ni 2 +，Cu 2 +，Zn的配合物在25°C和I = 0·10 M的条件下测量2 +，Cd 2+和Ag +。螯合物的形成发生在Ag +离子与能够形成“四半”或更大的螯合环的配体之间。没有证据表明所研究的其他金属离子会形成螯合物。在温度范围内的电位测量显示形成中的Ag + -allylacetate单复杂是一个大有利的焓变的结果（-17·5千焦耳摩尔-1由熵变化相对）（ Ť Δ小号= -6·在25°C时为0 kJ mol –1）。

  DOI：

  10.1039/dt9750000414
• 作为产物：
  描述：

  2-氯甲基四氢呋喃 在 吡啶 、 氢氧化钾 、 potassium Sodium 、 乙醚 、 乙醇 、 三溴化磷 作用下， 生成 2-(4-戊烯)丙二酸
  参考文献：
  名称：

  Gaubert; Linstead; Rydon, Journal of the Chemical Society, 1937, p. 1973

  摘要：

  DOI：

文献信息

• Palladium-Catalyzed Highly Diastereoselective Oxidative Cascade Cyclization Reactions
  作者：Kai-Tai Yip、Nian-Yong Zhu、Dan Yang

  DOI：10.1021/ol900355h

  日期：2009.5.7

  Isoquinoline and quinoline have been discovered as novel ligands for palladium-catalyzed oxidative cascade cyclization reactions. With our new catalyst systems (Pd(OAc)2/isoquinoline or quinoline), unsaturated anilides cyclize under an oxygen atmosphere (1 atm) to furnish structurally versatile indoline derivatives in good yields. One C−N bond and two C−C bonds are formed in a single step with excellent

  已发现异喹啉和喹啉是钯催化的氧化级联环化反应的新型配体。借助我们的新型催化剂体系（Pd（OAc）2 /异喹啉或喹啉），不饱和酸酐在氧气气氛（1个大气压）下环化，从而以高收率提供结构多样的二氢吲哚衍生物。一步形成一个C-N键和两个C-C键，非对映选择性极好（dr> 24：1）。
• Multifunctional curing agents and their use in improving strength of composites containing carbon fibers embedded in polymeric matrix
  申请人：UT-Battelle, LLC

  公开号：US10240011B2

  公开（公告）日：2019-03-26

  A functionalized carbon fiber having covalently bound on its surface a sizing agent containing epoxy groups, at least some of which are engaged in covalent bonds with crosslinking molecules, wherein each of said crosslinking molecules possesses at least two epoxy-reactive groups and at least one free functional group reactive with functional groups of a polymer matrix in which the carbon fiber is to be incorporated, wherein at least a portion of said cros slinking molecules are engaged, via at least two of their epoxy-reactive groups, in crosslinking bonds between at least two epoxy groups of the sizing agent. Composites comprised of these functionalized carbon fibers embedded in a polymeric matrix are also described. Methods for producing the functionalized carbon fibers and composites thereof are also described.

  一种功能化碳纤维，其表面共价结合了一种含有环氧基团的上浆剂，其中至少有一部分与交联分子以共价键结合，其中每个交联分子都具有至少两个环氧反应基团和至少一个与碳纤维所结合的聚合物基体的官能团反应的自由官能团、其中，至少有一部分所述交联分子通过至少两个环氧反应基团参与上浆剂的至少两个环氧基团之间的交联键。此外，还介绍了由嵌入聚合物基体中的这些功能化碳纤维组成的复合材料。此外，还介绍了生产功能化碳纤维及其复合材料的方法。
• Julia,M.; Maumy,M., Bulletin de la Societe Chimique de France, 1969, p. 2415 - 2427
  作者：Julia,M.、Maumy,M.

  DOI：——

  日期：——
• Intramolecular 1,4-Dipolar Cycloadditions of Cross-Conjugated Heteroaromatic Betaines. Synthesis of Hexahydrojulolidines and Related Peri- and Ortho-Fused Ring Systems
  作者：Kevin T. Potts、Thevarak Rochanapruk、Albert Padwa、Steven J. Coats、Lazaros Hadjiarapoglou

  DOI：10.1021/jo00117a035

  日期：1995.6

  3-Alkenyl 2-lactams react with (chlorocarbonyl)phenylketene to give nonisolable anhydro-4-hydroxy-2-oxo-1,3-oxazinium hydroxides which undergo regio- and stereospecific 1,4-dipolar cycloaddition in moderate yields to produce cycloadducts containing a carbon dioxide bridge. Thermolysis of the cycloadduct led to extrusion of carbon dioxide via a nonconcerted 1,5-hydrogen shift to give julolidine-type derivatives. Two of the cycloadducts were characterized by single-crystal X-ray determinations. A significant enhancement in the overall yield of the cycloaddition occurred in related reactions using anhydro-4-hydroxy-2-oxo-1,3-thiazinium hydroxides obtained from 3-alkenyl-3-ethyl(or methyl) 2-thiolactams and a variety of 1,3-bielectrophiles such as (chlorocarbonyl)phenylketene, carbon suboxide, substituted malonyl dichlorides, and ethyl (chlorocarbonyl)acetate. The thiazinium betaines were often isolable, and in one instance, a single-crystal X-ray characterization was possible. Cycloaddition of the thiazinium betaines occurred in a regiospecific manner. The initially formed cycloadducts which retained the carbonyl sulfide bridge could be induced to lose COS on further heating. Julolidine-type derivatives were obtained principally via a nonconcerted process. Variation in lactam ring size, coupled with tether length and substituent in the 1,3-bielectrophile , enabled control of ring size, substituents, and whether an ortho- or peri-fused tricyclic system resulted from the overall cycloaddition. In contrast to the lactam system, the thiolactams require disubstitution in the 3-position to avoid proton loss in the intermediate betaine with formation of a 1,3-thiaioline-4,6-dione.
• Chain-Walking Strategy for Organic Synthesis: Catalytic Cycloisomerization of 1,<i>n</i>-Dienes
  作者：Takuya Kochi、Taro Hamasaki、Yuka Aoyama、Junichi Kawasaki、Fumitoshi Kakiuchi

  DOI：10.1021/ja308377u

  日期：2012.10.10

  The catalytic construction of carbon-carbon bonds in small organic molecules via chain walking is described. Catalytic cycloisomerization of 1,n-dienes via chain walking was achieved using a palladium-1,10-phenanthroline catalyst to form five-membered-ring products. By means of a cycloisomerization/hydrogenation protocol, 1,7- to 1,14-dienes were selectively converted to bicyclo[4.3.0]nonane derivatives. The use of chain walking provides a new method in organic synthesis to functionalize unreactive carbon-hydrogen bonds by letting the catalyst look for preferable bond-forming sites by moving around on the substrate.