4-(3-Phenylprop-1-en-2-yl)morpholine | 131769-20-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 4-(3-Phenylprop-1-en-2-yl)morpholine
• CAS: 131769-20-5
• 化学式: C₁₃H₁₇NO
• 分子量: 203.284
• InChiKey: DMWLNAHQJUJTEL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(3-Phenylprop-1-en-2-yl)morpholine 在 盐酸 作用下， 以 1,4-二氧六环 、 甲苯 为溶剂， 生成 2-benzyl-5-methyl-4-phenyl-4H-pyrano[3,2-c][1,2]benzothiazine 6,6-dioxide
  参考文献：
  名称：

  Croce, Piero Dalla; Rosa, Concetta La; Molinari, Henriette, Gazzetta Chimica Italiana, 1990, vol. 120, # 7, p. 443 - 448

  摘要：

  DOI：
• 作为产物：
  描述：

  吗啉 、 苯基丙酮 以 苯 为溶剂， 生成 4-(3-Phenylprop-1-en-2-yl)morpholine
  参考文献：
  名称：

  Acid catalysed reactions of 5-formyluracils with enamines. A facile synthesis of 5-acylvinyluracils

  摘要：

  5-Formyl-1,3-dimethyluracil (1) reacts with secondary amine derived enamines of ketones and aldehydes to provide 5-(acyvinyl)uracil derivatives. The presence of a CH3 group at C-6 of 1 induces a competitive annulation reaction. Depending on the bulk of substituents 5-(acylvinyl)uracils acquire cis -diene and E or Z configurations on the vinyl unit. Enamines derived from 1,3-cyclohexanedione and ethyl acetoacetate react with 1 in 1: 2 stoichiometric manner to provide 5-(9-xanthenyl)uracil and 5-(6-cycohexadienyl)uracil(X-ray) derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)00390-1

文献信息

• DALLA, CROCE PIERO;LA, ROSA CONCETTA;MOLINARI, HENRIETTE, GAZZ. CHIM. ITAL., 120,(1990) N, C. 443-448
  作者：DALLA, CROCE PIERO、LA, ROSA CONCETTA、MOLINARI, HENRIETTE

  DOI：——

  日期：——
• Acid catalysed reactions of 5-formyluracils with enamines. A facile synthesis of 5-acylvinyluracils
  作者：Harjit Singh、Dolly、Maninder Singh Hundal、Geeta Hundal、Palwinder Singh、Swapandeep Singh Chimni、Subodh Kumar

  DOI：10.1016/s0040-4020(98)00390-1

  日期：1998.6

  5-Formyl-1,3-dimethyluracil (1) reacts with secondary amine derived enamines of ketones and aldehydes to provide 5-(acyvinyl)uracil derivatives. The presence of a CH3 group at C-6 of 1 induces a competitive annulation reaction. Depending on the bulk of substituents 5-(acylvinyl)uracils acquire cis -diene and E or Z configurations on the vinyl unit. Enamines derived from 1,3-cyclohexanedione and ethyl acetoacetate react with 1 in 1: 2 stoichiometric manner to provide 5-(9-xanthenyl)uracil and 5-(6-cycohexadienyl)uracil(X-ray) derivatives. (C) 1998 Elsevier Science Ltd. All rights reserved.
• Croce, Piero Dalla; Rosa, Concetta La; Molinari, Henriette, Gazzetta Chimica Italiana, 1990, vol. 120, # 7, p. 443 - 448
  作者：Croce, Piero Dalla、Rosa, Concetta La、Molinari, Henriette

  DOI：——

  日期：——