6-(pivaloyloxy)hexanoic acid | 1266674-92-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-(pivaloyloxy)hexanoic acid
• 英文别名: 6-(2,2-Dimethylpropanoyloxy)hexanoic acid
• CAS: 1266674-92-3
• 化学式: C₁₁H₂₀O₄
• 分子量: 216.277
• InChiKey: YDFOKWFHDBSUMI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  5-pivaloxy-1-pentene 在 1,10-菲罗啉 、 potassium tert-butylate 、 copper (I) acetate 作用下， 以 甲苯 为溶剂， 60.0~100.0 ℃ 、101.33 kPa 条件下， 反应 13.0h， 生成 6-(pivaloyloxy)hexanoic acid
  参考文献：
  名称：

  Copper-Catalyzed Carboxylation of Alkylboranes with Carbon Dioxide: Formal Reductive Carboxylation of Terminal Alkenes

  摘要：

  Carboxylation of alkylboron compounds (alkyl-9-BBN) with CO2 proceeded in the presence of catalytic amounts of CuOAc/1,10-phenanthroline and a stoichiometric amount of (KOBu)-Bu-t. The alkylboranes are easily and widely available through the alkene hydroboration, and thus the overall process represents a reductive carboxylation of alkenes with CO2. The broad functional group compatibility and the inexpensiveness of the Cu/1,10-phenathoroline catalyst system are attractive features of this protocol.

  DOI：

  10.1021/ol103128x

文献信息

• AMINOTHIAZOLES AND THEIR USES
  申请人：Bushell Simon

  公开号：US20140315790A1

  公开（公告）日：2014-10-23

  The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases.

  本申请描述了对治疗、预防和/或改善疾病有用的有机化合物。
• GRADIENT OPTICAL POLYMER NANOCOMPOSITES
  申请人：State of Oregon acting by and through the State Board of Higher Education on behalf of the Univers

  公开号：US20150023643A1

  公开（公告）日：2015-01-22

  Gradient index optical materials are formed by drop by drop dispensing of nanoparticle/monomer suspensions. Refractive index variations are defined by nanoparticle concentrations that can vary in three dimensions. Droplets of differing compositions can be mixed, and droplets or layers or droplets are partially cross-linked by exposure to ultraviolet radiation prior to dispensing additional droplets. Gradient index optical elements such as lenses, prisms, and waveguides can be formed in flexible polymer layers.

  渐变折射率光学材料是通过滴滴分配纳米颗粒/单体悬浮液形成的。折射率变化由纳米颗粒浓度在三个维度上变化定义。不同成分的液滴可以混合，液滴或液滴层可以在分配额外液滴之前通过紫外线辐射部分交联。可以在柔性聚合物层中形成渐变折射率光学元件，如透镜、棱镜和波导。
• OPTICAL MEMBER SET AND SOLID-STATE IMAGING ELEMENT USING THE SAME
  申请人：FUJIFILM CORPORATION

  公开号：US20140285695A1

  公开（公告）日：2014-09-25

  An optical member set which has a first optical member formed by curing a composition of curable resins, and a second optical member which is covered by the first optical member, in which the contact angle with water on a surface, which comes into contact with a first optical member, of the second optical member is 70 to 97° and the contact angle with the water on a surface of the opposite side to the side, which comes into contact with the second optical member, of the first optical member is 80 to 115°.
• US9513406B2
  申请人：——

  公开号：US9513406B2

  公开（公告）日：2016-12-06
• US9625618B2
  申请人：——

  公开号：US9625618B2

  公开（公告）日：2017-04-18