(1S,2S,6S,7S,9S,11S)-9-methoxy-4,4-dimethyl-3,5,8,10-tetraoxatricyclo[5.2.2.02,6]undecane-1,11-diol | 145933-66-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧吡喃
• 英文名称: (1S,2S,6S,7S,9S,11S)-9-methoxy-4,4-dimethyl-3,5,8,10-tetraoxatricyclo[5.2.2.02,6]undecane-1,11-diol
• CAS: 145933-66-0
• 化学式: C₁₀H₁₆O₇
• 分子量: 248.233
• InChiKey: YMGZKPZDSIZEFG-YDNOQEIHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  86.6
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  (1S,2S,6S,7S,9S,11S)-9-methoxy-4,4-dimethyl-3,5,8,10-tetraoxatricyclo[5.2.2.02,6]undecane-1,11-diol 以 苯 为溶剂， 以100%的产率得到
  参考文献：
  名称：

  2,5-dioxabicyclo[2.2.2]octane ring systems in the tautomeric forms of D-lyxo-hexopyranosid-2-ulose, 1,5-anhydro-D-tagatose and D-lyxo-hexodialdo-1,5-pyranosid-2-ulose derivatives

  摘要：

  3,4-O-Isopropylidene derivatives of the title compounds have been prepared by new methods and found to exhibit a high preference for tautomeric forms deriving from hemiacetalization between 6-CH2OH, or 6-CH(OH)2, and 2-C=O functions.

  DOI：

  10.1016/s0040-4039(00)60933-4
• 作为产物：
  描述：

  methyl 3,4-O-isopropylidene-α-D-galactopyranoside 在 二甲基亚砜 、 N,N'-二环己基碳二亚胺 作用下， 以55%的产率得到(1S,2S,6S,7S,9S,11S)-9-methoxy-4,4-dimethyl-3,5,8,10-tetraoxatricyclo[5.2.2.02,6]undecane-1,11-diol
  参考文献：
  名称：

  2,5-dioxabicyclo[2.2.2]octane ring systems in the tautomeric forms of D-lyxo-hexopyranosid-2-ulose, 1,5-anhydro-D-tagatose and D-lyxo-hexodialdo-1,5-pyranosid-2-ulose derivatives

  摘要：

  3,4-O-Isopropylidene derivatives of the title compounds have been prepared by new methods and found to exhibit a high preference for tautomeric forms deriving from hemiacetalization between 6-CH2OH, or 6-CH(OH)2, and 2-C=O functions.

  DOI：

  10.1016/s0040-4039(00)60933-4

文献信息

• 2,5-dioxabicyclo[2.2.2]octane ring systems in the tautomeric forms of D-lyxo-hexopyranosid-2-ulose, 1,5-anhydro-D-tagatose and D-lyxo-hexodialdo-1,5-pyranosid-2-ulose derivatives
  作者：Pier Luigi Barili、Giancarlo Berti、Felicia D'Andrea、Valeria Di Bussolo、Anna Gaudiosi

  DOI：10.1016/s0040-4039(00)60933-4

  日期：1992.11

  3,4-O-Isopropylidene derivatives of the title compounds have been prepared by new methods and found to exhibit a high preference for tautomeric forms deriving from hemiacetalization between 6-CH2OH, or 6-CH(OH)2, and 2-C=O functions.