1,2-Bis<2-(2-formylbenzyl)benzyl>benzene | 154618-87-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 1,2-Bis<2-(2-formylbenzyl)benzyl>benzene
• 英文别名: 1,2-Bis[2-(2-formylbenzyl)benzyl]benzene；2-[[2-[[2-[[2-[(2-Formylphenyl)methyl]phenyl]methyl]phenyl]methyl]phenyl]methyl]benzaldehyde
• CAS: 154618-87-8
• 化学式: C₃₆H₃₀O₂
• 分子量: 494.633
• InChiKey: YRDAXPWSQUZJJP-UHFFFAOYSA-N

物化性质

• 沸点：
  651.5±50.0 °C(predicted)
• 密度：
  1.149±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  38
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,2-Bis<2-(2-formylbenzyl)benzyl>benzene 在 正丁基锂 、 Celite 、 pyridinium chlorochromate 作用下， 以 二氯甲烷 为溶剂， 反应 48.0h， 生成 <1₇>Orthocyclophane-1,3-dione
  参考文献：
  名称：

  Orthocyclophanes. 3. Ketonands, Novel Ketonic Crowns of Polyoxo[1n]orthocyclophane Constitution

  摘要：

  Synthetic studies of a new family of novel ketonic macrocycles are reported. Exhaustive oxidation of all of the methylenes in odd-numbered [1(n)]orthocyclophanes ([1(n)]OCPs) resulted in the polyoxo derivatives of a cyclopolyorthobenzoyl or polyoxo[1(n)]orthocyclophane constitution. This new class of ketonic crowns is referred to as [1(n)]orthocyclophanepolyones and includes [1(5)] orthocyclophane-pentaone, [1(7)]orthocyclophaneheptaone, and [1(9)]orthocyclophanenonaone. We suggest the generic name ''ketonands'' for these ketonic crowns. Structures of ketonands were confirmed by spectral and X-ray crystallographic analyses.

  DOI：

  10.1021/jo00083a033
• 作为产物：
  描述：

  2-(tetrahydropyranyloxy)methylbromobenzene 在 copper(l) iodide 、 Celite 、 对甲苯磺酸 、 magnesium 、 pyridinium chlorochromate 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 12.0h， 生成 1,2-Bis<2-(2-formylbenzyl)benzyl>benzene
  参考文献：
  名称：

  Orthocyclophanes. 3. Ketonands, Novel Ketonic Crowns of Polyoxo[1n]orthocyclophane Constitution

  摘要：

  Synthetic studies of a new family of novel ketonic macrocycles are reported. Exhaustive oxidation of all of the methylenes in odd-numbered [1(n)]orthocyclophanes ([1(n)]OCPs) resulted in the polyoxo derivatives of a cyclopolyorthobenzoyl or polyoxo[1(n)]orthocyclophane constitution. This new class of ketonic crowns is referred to as [1(n)]orthocyclophanepolyones and includes [1(5)] orthocyclophane-pentaone, [1(7)]orthocyclophaneheptaone, and [1(9)]orthocyclophanenonaone. We suggest the generic name ''ketonands'' for these ketonic crowns. Structures of ketonands were confirmed by spectral and X-ray crystallographic analyses.

  DOI：

  10.1021/jo00083a033

文献信息

• Orthocyclophanes. 4. Functionalization of [1n]Orthocyclophanes on the Aromatic Rings
  作者：Woo Young Lee、Chang Hee Park、Eun Hee Kim

  DOI：10.1021/jo00095a026

  日期：1994.8

  Functionalization of the [1(n)]orthocyclophanes ([1(n)]OCPs) has been accomplished by introducing groups on the aromatic rings of the cycles. Dilithiation of dibromoaromatic 10 followed by condensation with various aromatic dialdehydes, such as 14, 20, and 30, gave rise to [1(n)]OCP cycles bearing methoxy groups on the aromatic rings. Several polymethoxy[1(n)]OCPs have been prepared that are reasonably soluble inorganic solvents, in contrast to their parent hydrocarbons. Since methoxy functions can be converted to phenolic hydroxy groups and then to other functionalities, the methoxy derivatives may have broad applications to the modification of [1(n)]OCPs for the preparation of a variety of supramolecules.