丙二醇二辛酸酯 | 56519-71-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 丙二醇二辛酸酯
• 英文名称: 1,3-propanediyl dicaprylate
• 英文别名: 1,3-propanediol dicaprylate；3-hydroxypropyl dicaprylate；1,3-Propandiol-dioctanoat；1,3-bis-octanoyloxy-propane；1,3-Bis-octanoyloxy-propan；Octanoic acid, 1,3-propanediyl ester；3-octanoyloxypropyl octanoate
• CAS: 56519-71-2
• 化学式: C₁₉H₃₆O₄
• 分子量: 328.492
• InChiKey: XBBMJUWOCGWHRP-UHFFFAOYSA-N

物化性质

• 沸点：
  352℃ at 101.325kPa
• 密度：
  0.93 at 20℃
• LogP：
  7.6 at 22℃

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  23
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  乙醇 、 丙二醇二辛酸酯 在 Mo(Oxo)/C 作用下， 90.0 ℃ 、1.38 MPa 条件下， 反应 2.0h， 以17%的产率得到辛酸丙酯
  参考文献：
  名称：

  Efficient Catalytic Greenhouse Gas-Free Hydrogen and Aldehyde Formation from Alcohols

  摘要：

  从醇类（包括生物醇类）中催化制备氢气和醛类化合物，无需产生一氧化碳或二氧化碳。

  公开号：

  US20170297988A1
• 作为产物：
  描述：

  辛酸 、 1,3-丙二醇 生成 丙二醇二辛酸酯
  参考文献：
  名称：

  Breusch; Oguzer, Chemische Berichte, 1955, vol. 88, p. 1511,1516,1518

  摘要：

  DOI：

文献信息

• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• REVERSIBLY THERMOCHROMIC COMPOSITION
  申请人：Kabushiki Kaisha Pilot Corporation

  公开号：EP2772523A1

  公开（公告）日：2014-09-03

  [Object] To provide a reversibly thermochromic composition free from accidental discoloration by heat conducting from the opposite side writing surface or by self-heating due to quick writing; and also to provide a solid writing material and a writing ink composition comprising that composition. [Means to solve the problem] A reversibly thermochromic composition comprising a combination of: (a) a reversibly thermochromic component capable of being discolored or decolored by heat and (b) a component for controlling heat conducting to the reversibly thermochromic component; and also a solid writing material and a writing ink composition comprising that composition.

  [目的]提供一种可逆热致变色组合物，该组合物不会因反面书写面的热传导或快速书写导致的自热而意外变色；还提供一种固体书写材料和包含该组合物的书写墨水组合物。 [解决问题的方法] 一种可逆热致变色组合物，由以下物质组合而成：(a) 能够受热变色或脱色的可逆热致变色成分和 (b) 用于控制热量传导至可逆热致变色成分的成分；以及包含该成分的固体书写材料和书写墨水组合物。
• Cosmetic compositions as well as use of a cosmetic composition and method using same for removing waterproof make-up
  申请人：SCA Tissue France

  公开号：EP2921159A1

  公开（公告）日：2015-09-23

  The present invention relates to a use of a cosmetic composition for removing make-up, in particular waterproof make-up, wherein the cosmetic composition is in the form of a water-in-oil emulsion. The cosmetic composition, which is coated onto or impregnated into an applicator for cosmetic purpose, such as a pad, comprises an oil component having a polarity of at least 20 mN/m, water, and an emulsifier component comprising a lipophilic non-ionic emulsifier. According to another aspect, the invention relates to a method for removing make-up, especially waterproof make-up, comprising applying the above cosmetic composition to the skin. Further, the present invention is concerned with a specific cosmetic composition comprising water, an emulsifier component comprising a lipophilic non-ionic emulsifier, and an oil component which is a mixture of C12-C16 alkane and a cyclic silicone, in particular a cyclopentasiloxane and/or cyclohexasiloxane, and also to an applicator for cosmetic purpose impregnated or coated with such cosmetic composition. The present invention allows a highly efficient removal of waterproof make-up while reducing or avoiding the formation of an oily or greasy film with heavy texture on the skin upon use.

  本发明涉及一种用于卸妆，特别是卸防水妆的化妆品组合物，其中该化妆品组合物为油包水乳液形式。该化妆品组合物涂在或浸渍在用于化妆品的涂抹器（如化妆棉）上，包括极性至少为 20 mN/m 的油成分、水和乳化剂成分，乳化剂成分包括亲脂性非离子乳化剂。根据另一个方面，本发明涉及一种卸妆方法，尤其是卸防水妆的方法，包括将上述化妆品组合物涂在皮肤上。此外，本发明还涉及一种特定的化妆品组合物，该组合物包括水、由亲油性非离子乳化剂组成的乳化剂成分、以及由 C12-C16 烷烃和环状硅氧烷（尤其是环五硅氧烷和/或环己硅氧烷）组成的混合物油成分；本发明还涉及一种浸渍或涂覆有上述化妆品组合物的化妆品用涂抹器。本发明可以高效地卸除防水化妆品，同时减少或避免在使用时在皮肤上形成质地厚重的油性或油脂膜。
• LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS
  申请人：Novartis AG

  公开号：EP4019506A1

  公开（公告）日：2022-06-29

  This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1-R3, n, p, L1 and L2 are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.

  本发明提供了一种式 (I) 的化合物： 或其药学上可接受的盐，其中 R1-R3、n、p、L1 和 L2 在本文中定义。式（I）化合物及其药学上可接受的盐是一种阳离子脂质，可用于向细胞和组织递送生物活性剂。